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RBFOX1 / A2BP1
RNA binding protein, fox-1 homolog (C. elegans) 1
The Fox-1 family of RNA-binding proteins is evolutionarily conserved, and regulates tissue-specific alternative splicing in metazoa. Fox-1 recognizes a (U)GCAUG stretch in regulated exons or in flanking introns. The protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the product of the SCA2 gene which causes familial neurodegenerative diseases. Fox-1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.
| Gene Name: | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| Synonyms: | RBFOX1, A2BP1, 2BP1, Ataxin 2-binding protein 1, A2BP, FOX-1, FOX1, Ataxin-2-binding protein 1, Fox-1 homolog A, HRNBP1 |
| Target Sequences: | NM_018723 NP_061193.2 Q9NWB1 |
Publications (1)
1
Rbfox proteins regulate tissue-specific alternative splicing of Mef2D required for muscle differentiation. Runfola V, Sebastian S, Dilworth FJ, Gabellini D. Journal of cell science. 2015 128:631-7. (ICC; Mouse)
[Full Text Article]
[PubMed:25609712]
[PMC:PMC4357529]
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RBFOX1 / A2BP1 Rabbit anti-Human Polyclonal (aa81-130) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
RBFOX1 / A2BP1 Rabbit anti-Human Polyclonal (aa81-130) (HRP) Antibody
Rabbit, Mouse, Dog, Bovine, Rat, Pig, Horse, Bat, Orangutan, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
RBFOX1 / A2BP1 Rabbit anti-Human Polyclonal (aa81-130) (Biotin) Antibody
Rabbit, Mouse, Dog, Bovine, Rat, Pig, Horse, Bat, Orangutan, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
RBFOX1 / A2BP1 Rabbit anti-Human Polyclonal (aa81-130) (FITC) Antibody
Rabbit, Mouse, Dog, Bovine, Rat, Pig, Horse, Bat, Orangutan, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
RBFOX1 / A2BP1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
RBFOX1 / A2BP1 Mouse anti-Human Monoclonal (aa1-210) (OTI4F9) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
RBFOX1 / A2BP1 Mouse anti-Human Monoclonal (aa1-210) (Carrier-free) (OTI4F9) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
RBFOX1 / A2BP1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
RBFOX1 / A2BP1 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody
Mouse, Dog, Bovine, Rat, Horse, Orangutan, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
RBFOX1 / A2BP1 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Mouse, Dog, Bovine, Rat, Horse, Orangutan, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
RBFOX1 / A2BP1 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Mouse, Dog, Bovine, Rat, Horse, Orangutan, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
RBFOX1 / A2BP1 Mouse anti-Human Monoclonal (aa1-210) (OTI2C12) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
RBFOX1 / A2BP1 Mouse anti-Human Monoclonal (aa1-210) (Carrier-free) (OTI2C12) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
RBFOX1 / A2BP1 Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF, IHC-P
Unconjugated
100 µl/$412
RBFOX1 / A2BP1 Mouse anti-Human Monoclonal (aa1-210) (OTI1F7) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
RBFOX1 / A2BP1 Mouse anti-Human Monoclonal (aa1-210) (Carrier-free) (OTI1F7) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
RBFOX1 / A2BP1 Mouse anti-Human Monoclonal (aa1-210) (OTI2D10) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
RBFOX1 / A2BP1 Mouse anti-Human Monoclonal (aa1-210) (Carrier-free) (OTI2D10) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
RBFOX1 / A2BP1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
RBFOX1 / A2BP1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
RBFOX1 / A2BP1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
RBFOX1 / A2BP1 Mouse anti-Rat Monoclonal (1G10) Antibody
Mouse, Bovine, Rat, Human
IF, WB
Unconjugated
100 µl/$469
RBFOX1 / A2BP1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$357
RBFOX1 / A2BP1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
RBFOX1 / A2BP1 Rabbit anti-Mouse Polyclonal (aa51-100) Antibody
Mouse
WB
Unconjugated
100 µl/$424
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