RASGRP4

RAS guanyl releasing protein 4

RASGRP4 is a member of the Ras guanyl nucleotide-releasing protein (RasGRP) family of Ras guanine nucleotide exchange factors. It contains a Ras exchange motif, a diacylglycerol-binding domain, and two calcium-binding EF hands. This protein was shown to activate H-Ras in a cation-dependent manner in vitro. Expression of this protein in myeloid cell lines was found to be correlated with elevated level of activated RAS protein, and the RAS activation can be greatly enhanced by phorbol ester treatment, which suggested a role of this protein in diacylglycerol regulated cell signaling pathways. Studies of a mast cell leukemia cell line expressing substantial amounts of abnormal transcripts of this gene indicated that this gene may play an important role in the final stages of mast cell development. Multiple transcript variants encoding different isoforms have been found for this gene.

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Products

Proteins (12)

Antibodies (8)

Type

Over-Expression Lysate (10)

Primary (8)

Recombinant (2)

Target

RASGRP4 (20)

Reactivity

Human (7)

Mouse (1)

Gibbon (3)

Application

IHC (3)

IHC-P (3)

WB (8)

ELISA (3)

ICC (1)

IF (1)

Host

rabbit (6)

mouse (2)

Isotype

IgG2a,k (2)

Clonality

monoclonal mc (2)

polyclonal pc (6)

Clone

1F3 (1)

6D3 (1)

Format

Biotin Conjugated (1)

FITC Conjugated (1)

HRP Conjugated (1)

Unconjugated (5)

Epitope

aa149-198 (4)

Internal (1)

aa108-200 (1)

Publications

No (20)

Tag

GST (1)

GST, N-terminus (1)

Myc-DDK (Flag) (10)

Species

Human (7)

Source

293T Cells (5)

HEK 293 Cells (5)

Wheat Germ Extract (2)

Purification

Purified (1)

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RASGRP4 Antibody (Internal) LS-C145016

Antibody:

RASGRP4 Rabbit anti-Mouse Polyclonal (Internal) Antibody

Reactivity:

Mouse

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

100 µl/$440; 200 µl/$468

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RASGRP4 Antibody (aa108-200) LS-C185646

Antibody:

RASGRP4 Rabbit anti-Human Polyclonal (aa108-200) Antibody

Reactivity:

Human

Applications:

ICC, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$450

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RASGRP4 Antibody (aa149-198) LS-C145724

Antibody:

RASGRP4 Rabbit anti-Human Polyclonal (aa149-198) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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RASGRP4 Antibody (aa149-198, HRP) LS-C469455

Antibody:

RASGRP4 Rabbit anti-Human Polyclonal (aa149-198) (HRP) Antibody

Reactivity:

Human, Gibbon

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

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RASGRP4 Antibody (aa149-198, Biotin) LS-C469453

Antibody:

RASGRP4 Rabbit anti-Human Polyclonal (aa149-198) (Biotin) Antibody

Reactivity:

Human, Gibbon

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

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RASGRP4 Antibody (aa149-198, FITC) LS-C469454

Antibody:

RASGRP4 Rabbit anti-Human Polyclonal (aa149-198) (FITC) Antibody

Reactivity:

Human, Gibbon

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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RASGRP4 Antibody (clone 1F3) LS-C133831

Antibody:

RASGRP4 Mouse anti-Human Monoclonal (1F3) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$423

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RASGRP4 Antibody (clone 6D3) LS-C133832

Antibody:

RASGRP4 Mouse anti-Human Monoclonal (6D3) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$423

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Human RASGRP4 Protein (Recombinant GST, N-terminus) (aa574-673) - LS-G63566

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human RASGRP4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G93232

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

66.8 kDa

Price:

20 µg/$150

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Human RASGRP4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G93233

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

71.1 kDa

Price:

20 µg/$150

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Human RASGRP4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G93234

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

53.7 kDa

Price:

20 µg/$150

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Human RASGRP4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G93235

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

64.1 kDa

Price:

20 µg/$150

Select

Human RASGRP4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G93236

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

74.7 kDa

Price:

20 µg/$215

Select

Human RASGRP4 Protein (Recombinant GST) (Full Length) - LS-G36228

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

101.3 kDa

Price:

2 µg/$439

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RASGRP4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G105643

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

74.7 kDa

Price:

100 µg/$710

Select

RASGRP4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G128270

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

66.8 kDa

Price:

100 µg/$494

Select

RASGRP4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G128289

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

71.1 kDa

Price:

100 µg/$494

Select

RASGRP4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G128245

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

64.1 kDa

Price:

100 µg/$494

Select

RASGRP4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G128176

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

53.7 kDa

Price:

100 µg/$494

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