RASGRP1 / RASGRP

RAS guanyl releasing protein 1 (calcium and DAG-regulated)

This gene is a member of a family of genes characterized by the presence of a Ras superfamily guanine nucleotide exchange factor (GEF) domain. It functions as a diacylglycerol (DAG)-regulated nucleotide exchange factor specifically activating Ras through the exchange of bound GDP for GTP. It activates the Erk/MAP kinase cascade and regulates T-cells and B-cells development, homeostasis and differentiation. Alternatively spliced transcript variants encoding different isoforms have been identified. Altered expression of the different isoforms of this protein may be a cause of susceptibility to systemic lupus erythematosus (SLE).

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Proteins (3)

Type

Over-Expression Lysate (2)

Recombinant (1)

Target

RASGRP1 / RASGRP (3)

Publications

No (3)

Tag

Myc-DDK (Flag) (3)

Species

Human (2)

Source

293T Cells (1)

HEK 293 Cells (2)

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Human RASGRP1 / RASGRP Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G87656

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

90.2 kDa

Price:

20 µg/$215

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Human RASGRP1 / RASGRP Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G70651

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

90.2 kDa

Price:

20 µg/$1,107

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RASGRP1 / RASGRP Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G115762

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

90.2 kDa

Price:

100 µg/$710

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