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RASGRF1 / CDC25

Ras protein-specific guanine nucleotide-releasing factor 1

RASGRF1 / CDC25 is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. The studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Gene Name: Ras protein-specific guanine nucleotide-releasing factor 1
Synonyms: RASGRF1, CDC25, CDC25L, GNRP, GRF55, H-GRF55, PP13187, CDC25 homolog, GRF1, Ras-GRF1
Target Sequences: NM_002891 NP_002882.3 Q13972

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Products
Proteins (7)
Over-Expression Lysate (4)
Recombinant (3)
RASGRF1 / CDC25 (7)
No (7)
GST, N-terminus (1)
His-T7 (1)
Myc-DDK (Flag) (5)
Human (5)
293T Cells (2)
E. coli (1)
HEK 293 Cells (3)
Wheat Germ Extract (1)
RASGRF1 / CDC25 Protein - Purified recombinant protein RASGRF1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
145.1 kDa
20 µg/$1,107
RASGRF1 / CDC25 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
55.3 kDa
100 µg/$710
RASGRF1 / CDC25 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
145.1 kDa
100 µg/$710
RASGRF1 / CDC25 Protein - Recombinant  Cell Division Cycle Protein 25 By SDS-PAGE
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E. coli
His-T7
21.8 kDa
10 µg/$279; 50 µg/$427; 100 µg/$682; 200 µg/$852; 1 mg/$1,950; 500 µg/$1,494; 5 mg/$2,983; 2 mg/$2,136
RASGRF1 / CDC25 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
RASGRF1 / CDC25 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
145.1 kDa
20 µg/$215
RASGRF1 / CDC25 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
55.3 kDa
20 µg/$215
Viewing 1-7 of 7 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).