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RARRES3
retinoic acid receptor responder (tazarotene induced) 3
Retinoids exert biologic effects such as potent growth inhibitory and cell differentiation activities and are used in the treatment of hyperproliferative dermatological diseases. These effects are mediated by specific nuclear receptor proteins that are members of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. RARRES1, RARRES2, and RARRES3 are genes whose expression is upregulated by the synthetic retinoid tazarotene. RARRES3 is thought act as a tumor suppressor or growth regulator.
| Gene Name: | retinoic acid receptor responder (tazarotene induced) 3 |
| Synonyms: | RARRES3, HRASLS4, TIG3, PLA1/2-3, RAR-responsive protein TIG3, Retinoic acid-inducible gene 1, RIG1 |
| Target Sequences: | NM_004585 NP_004576.2 Q9UL19 |
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