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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
Protein Family And Group
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RAPGEF5 / GFR

Rap guanine nucleotide exchange factor (GEF) 5

Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF5, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]).

Gene Name: Rap guanine nucleotide exchange factor (GEF) 5
Synonyms: RAPGEF5, GFR, KIAA0277, M-Ras-regulated Rap GEF, M-Ras-regulated GEF, MRGEF, Related to Epac, REPAC, MR-GEF
Target Sequences: D87467 BAA13406.2 Q92565

Viewing 1-21 of 21 items
RAPGEF5 / GFR Antibody - Anti-RAPGEF5 / GFR antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
Select
Rabbit Polyclonal (IgG) to Human RAPGEF5 / GFR
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50µl   1mg/ml   $425.00
RAPGEF5 / GFR Antibody - Immunohistochemistry of paraffin-embedded human testis tissue using antibody at dilution of 1:100.
Select
Rabbit Polyclonal (IgG) to Human RAPGEF5 / GFR
Human
ELISA, IHC, IHC-P
Unconjugated
50µg   $285.00; 100µg   $385.00
Select
Rabbit Polyclonal (IgG) to Human RAPGEF5 / GFR
Human
ELISA, IHC
HRP Conjugated
50µg   $285.00; 100µg   $385.00
Select
Rabbit Polyclonal (IgG) to Human RAPGEF5 / GFR
Human
ELISA, IHC
Biotin Conjugated
50µg   $285.00; 100µg   $385.00
Select
Rabbit Polyclonal (IgG) to Human RAPGEF5 / GFR
Human
ELISA, IHC
FITC Conjugated
50µg   $285.00; 100µg   $385.00
RAPGEF5 / GFR Antibody
Select
Rabbit Polyclonal (IgG) to Human RAPGEF5 / GFR
Mouse, Rat, Human
ELISA, IF, WB
Unconjugated
100µl   1mg/ml   $325.00; 200µl   1mg/ml   $375.00
Select
Rabbit Polyclonal (IgG) to Human RAPGEF5 / GFR
Human
ELISA, WB
Unconjugated
200µl   $590.00
Select
Rabbit Polyclonal (IgG) to Human RAPGEF5 / GFR
Human
ELISA, WB
Biotin Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human RAPGEF5 / GFR
Human
ELISA, WB
FITC Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human RAPGEF5 / GFR
Human
ELISA, WB
AP Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human RAPGEF5 / GFR
Human
ELISA, WB
HRP Conjugated, Azide-free
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human RAPGEF5 / GFR
Human
ELISA, WB
PE Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human RAPGEF5 / GFR
Human
ELISA, WB
APC Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human RAPGEF5 / GFR
Mouse, Rat, Human
ELISA, WB
Unconjugated
50µl   1mg/ml   $235.00; 100µl   1mg/ml   $265.00; 200µl   1mg/ml   $335.00
Select
Rabbit Polyclonal (IgG) to Human RAPGEF5 / GFR
Human
ELISA, WB
Unconjugated
100µg   $375.00
RAPGEF5 / GFR Antibody - Western blot analysis of extracts from RAW264.7 cells, using RAPGEF5 antibody.
Select
Rabbit Polyclonal (IgG) to Human RAPGEF5 / GFR
Mouse, Rat, Human
ELISA, WB
Unconjugated
100µg   $305.00
RAPGEF5 / GFR Antibody - Western blot analysis of lysates from RAW264.7 cells, using RAPGEF5 Antibody. The lane on the right is blocked with the synthesized peptide.
Select
Rabbit Polyclonal (IgG) to Human RAPGEF5 / GFR
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
50µl   1mg/ml   $265.00; 100µl   1mg/ml   $325.00
Select
Rabbit Polyclonal to Human RAPGEF5 / GFR
Mouse, Rat, Human
WB
Unconjugated
100µl   $345.00
RAPGEF5 / GFR Antibody - RAPGEF5 Antibody western blot of HepG2 cell line lysates (35 ug/lane). The RAPGEF5 antibody detected the RAPGEF5 protein (arrow).
Select
Rabbit Polyclonal to Human RAPGEF5 / GFR
Human
WB
Unconjugated
400µl   $325.00
RAPGEF5 / GFR Antibody - Sample (30 ug of whole cell lysate). A: HeLa S3. 7.5% SDS PAGE. RAPGEF5 / GFR antibody diluted at 1:1000
Select
Rabbit Polyclonal (IgG) to Human RAPGEF5 / GFR
Human
WB
Unconjugated
100µl   0.74mg/ml   $355.00
RAPGEF5 / GFR Antibody - Western blot analysis of GFR expression in K562 (A); Raw264.7 (B); H9C2 (C) whole cell lysates.
Select
Rabbit Polyclonal to Human RAPGEF5 / GFR
Mouse, Rat, Human
WB
Unconjugated
100µl   1mg/ml   $245.00

Viewing 1-21 of 21 items


If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).