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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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RAPGEF5 / GFR

Rap guanine nucleotide exchange factor (GEF) 5

Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF5, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]).

Gene Name: Rap guanine nucleotide exchange factor (GEF) 5
Synonyms: RAPGEF5, GFR, KIAA0277, M-Ras-regulated Rap GEF, M-Ras-regulated GEF, MRGEF, Related to Epac, REPAC, MR-GEF
Target Sequences: D87467 BAA13406.2 Q92565

Filtered By: None
Target
RAPGEF5 / GFR (19)
Reactivity
Human (19)
Mouse (5)
Rat (5)
Application
IHC (5)
IHC-P (2)
WB (15)
ELISA (13)
Peptide-ELISA (2)
Host
rabbit (19)
Isotype
IgG (16)
Clonality
polyclonal pc (19)
Format
AP Conjugated (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Unconjugated (10)
Epitope
aa529-555 (8)
400-480 aa, Internal (1)
Internal (1)
aa1-179 (1)
aa417-466 (1)
aa431-480 (1)
aa476-521 (1)
Publications
No (19)
Showing 1-19 of 19 results

RAPGEF5 / GFR Antibody (aa417-466) IHC-plus™ LS-B11458
Rabbit Polyclonal (IgG) to Human RAPGEF5 / GFR
Mouse, Rat, Human
IHC IHC-P Peptide-ELISA WB
Unconjugated
50µl 1mg/ml  $425.00
Anti-RAPGEF5 / GFR antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
Western blot analysis of the lysates from COLO205 cells using RAPGEF5 antibody.
Anti-RAPGEF5 / GFR antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
Western blot analysis of the lysates from COLO205 cells using RAPGEF5 antibody.

RAPGEF5 / GFR Antibody LS-C378206
Rabbit Polyclonal (IgG) to Human RAPGEF5 / GFR
Human
ELISA IHC IHC-P
Unconjugated
50µg  $285.00; 100µg  $385.00
Immunohistochemistry of paraffin-embedded human testis tissue using antibody at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human spleen tissue using antibody at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human testis tissue using antibody at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human spleen tissue using antibody at dilution of 1:100.

RAPGEF5 / GFR Antibody (HRP) LS-C378210
Rabbit Polyclonal (IgG) to Human RAPGEF5 / GFR
Human
ELISA IHC
HRP Conjugated
50µg  $285.00; 100µg  $385.00

RAPGEF5 / GFR Antibody (Biotin) LS-C378208
Rabbit Polyclonal (IgG) to Human RAPGEF5 / GFR
Human
ELISA IHC
Biotin Conjugated
50µg  $285.00; 100µg  $385.00

RAPGEF5 / GFR Antibody (FITC) LS-C378214
Rabbit Polyclonal (IgG) to Human RAPGEF5 / GFR
Human
ELISA IHC
FITC Conjugated
50µg  $285.00; 100µg  $385.00

RAPGEF5 / GFR Antibody (aa529-555) LS-C324527
Rabbit Polyclonal (IgG) to Human RAPGEF5 / GFR
Human
ELISA WB
Unconjugated
200µl  $530.00

RAPGEF5 / GFR Antibody (aa529-555, Biotin) LS-C284976
Rabbit Polyclonal (IgG) to Human RAPGEF5 / GFR
Human
ELISA WB
Biotin Conjugated
200µl  $680.00

RAPGEF5 / GFR Antibody (aa529-555, FITC) LS-C284977
Rabbit Polyclonal (IgG) to Human RAPGEF5 / GFR
Human
ELISA WB
FITC Conjugated
200µl  $680.00

RAPGEF5 / GFR Antibody (aa529-555, PE) LS-C284979
Rabbit Polyclonal (IgG) to Human RAPGEF5 / GFR
Human
ELISA WB
PE Conjugated
200µl  $680.00

RAPGEF5 / GFR Antibody (aa529-555, Azide-free, HRP) LS-C284978
Rabbit Polyclonal (IgG) to Human RAPGEF5 / GFR
Human
ELISA WB
HRP Conjugated, Azide-free
200µl  $680.00

RAPGEF5 / GFR Antibody (aa529-555, AP) LS-C284974
Rabbit Polyclonal (IgG) to Human RAPGEF5 / GFR
Human
ELISA WB
AP Conjugated
200µl  $680.00

RAPGEF5 / GFR Antibody (aa529-555, APC) LS-C284975
Rabbit Polyclonal (IgG) to Human RAPGEF5 / GFR
Human
ELISA WB
APC Conjugated
200µl  $680.00

RAPGEF5 / GFR Antibody (400-480 aa, Internal) LS-C385815
Rabbit Polyclonal (IgG) to Human RAPGEF5 / GFR
Mouse, Rat, Human
ELISA WB
Unconjugated
100µl 1mg/ml  $265.00

RAPGEF5 / GFR Antibody LS-C753126
Rabbit Polyclonal (IgG) to Human RAPGEF5 / GFR
Human
ELISA WB
Unconjugated
100µg  $375.00

RAPGEF5 / GFR Antibody (aa431-480) LS-C120296
Rabbit Polyclonal (IgG) to Human RAPGEF5 / GFR
Mouse, Rat, Human
Peptide-ELISA WB
Unconjugated
50µl 1mg/ml  $265.00; 100µl 1mg/ml  $325.00
Western blot analysis of lysates from RAW264.7 cells, using RAPGEF5 Antibody. The lane on the right is blocked with the synthesized peptide.
Western blot analysis of lysates from RAW264.7 cells, using RAPGEF5 Antibody. The lane on the right is blocked with the synthesized peptide.

RAPGEF5 / GFR Antibody (aa476-521) LS-C313915
Rabbit Polyclonal to Human RAPGEF5 / GFR
Mouse, Rat, Human
WB
Unconjugated
100µl  $345.00

RAPGEF5 / GFR Antibody (aa529-555) LS-C162442
Rabbit Polyclonal to Human RAPGEF5 / GFR
Human
WB
Unconjugated
400µl  $305.00
RAPGEF5 Antibody western blot of HepG2 cell line lysates (35 ug/lane). The RAPGEF5 antibody detected the RAPGEF5 protein (arrow).
RAPGEF5 Antibody western blot of HepG2 cell line lysates (35 ug/lane). The RAPGEF5 antibody detected the RAPGEF5 protein (arrow).

RAPGEF5 / GFR Antibody (Internal) LS-C353196
Rabbit Polyclonal to Human RAPGEF5 / GFR
Mouse, Rat, Human
WB
Unconjugated
100µl 1mg/ml  $245.00
Western blot analysis of GFR expression in K562 (A); Raw264.7 (B); H9C2 (C) whole cell lysates.
Western blot analysis of GFR expression in K562 (A); Raw264.7 (B); H9C2 (C) whole cell lysates.

RAPGEF5 / GFR Antibody (aa1-179) LS-C185498
Rabbit Polyclonal (IgG) to Human RAPGEF5 / GFR
Human
WB
Unconjugated
100µl 0.74mg/ml  $335.00
Sample (30 ug of whole cell lysate). A: HeLa S3. 7.5% SDS PAGE. RAPGEF5 / GFR antibody diluted at 1:1000
Sample (30 ug of whole cell lysate). A: HeLa S3. 7.5% SDS PAGE. RAPGEF5 / GFR antibody diluted at 1:1000
Showing 1-19 of 19 results

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If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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