RANBP3

RAN binding protein 3

Acts as a cofactor for XPO1/CRM1-mediated nuclear export, perhaps as export complex scaffolding protein. Bound to XPO1/CRM1, stabilizes the XPO1/CRM1-cargo interaction. In the absence of Ran-bound GTP prevents binding of XPO1/CRM1 to the nuclear pore complex. Binds to CHC1/RCC1 and increases the guanine nucleotide exchange activity of CHC1/RCC1. Recruits XPO1/CRM1 to CHC1/RCC1 in a Ran-dependent manner. Negative regulator of TGF-beta signaling through interaction with the R-SMAD proteins, SMAD2 and SMAD3, and mediating their nuclear export.

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Products

Proteins (11)

Type

Over-Expression Lysate (6)

Recombinant (5)

Target

RANBP3 (11)

Publications

No (11)

Tag

GST (1)

GST, N-terminus (1)

His (1)

Myc-DDK (Flag) (8)

Species

Human (8)

Source

293T Cells (3)

E. coli (1)

HEK 293 Cells (5)

Wheat Germ Extract (2)

Purification

Purified (1)

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RANBP3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G114712

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

53.2 kDa

Price:

100 µg/$710

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RANBP3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G114713

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

60 kDa

Price:

100 µg/$710

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RANBP3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G117197

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

59.5 kDa

Price:

100 µg/$710

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Human RANBP3 Protein (Recombinant GST) (Full Length) - LS-G31176

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

68.8 kDa

Price:

10 µg/$479; 25 µg/$670

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Human RANBP3 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G68716

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

53.2 kDa

Price:

20 µg/$1,107

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Human RANBP3 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G68717

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

60 kDa

Price:

20 µg/$1,107

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Human RANBP3 Protein (Recombinant GST, N-terminus) (aa298-397) - LS-G60745

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human RANBP3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G82902

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

59.5 kDa

Price:

20 µg/$215

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Human RANBP3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G82903

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

53.2 kDa

Price:

20 µg/$215

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Human RANBP3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G82904

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

60 kDa

Price:

20 µg/$215

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Human RANBP3 Protein (Recombinant His) - LS-G2932

Source:

E. coli

Tag:

His

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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