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RAMP1

receptor (G protein-coupled) activity modifying protein 1

RAMP1 is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP1) protein, CRLR functions as a CGRP receptor. The RAMP1 protein is involved in the terminal glycosylation, maturation, and presentation of the CGRP receptor to the cell surface. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene Name: receptor (G protein-coupled) activity modifying protein 1
Synonyms: RAMP1
Target Sequences: NM_005855 NP_005846.1 O60894

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Proteins (5)
Over-Expression Lysate (2)
Recombinant (3)
RAMP1 (5)
No (5)
GST (1)
GST, N-terminus (1)
His (1)
Myc-DDK (Flag) (2)
Human (4)
293T Cells (1)
E. coli (1)
HEK 293 Cells (1)
Wheat Germ Extract (2)
Purified (2)
RAMP1 Protein - 12.5% SDS-PAGE of human RAMP1 stained with Coomassie Blue
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Wheat Germ Extract
GST
42.02 kDa
2 µg/$439
RAMP1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
RAMP1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
16.99 kDa
100 µg/$494
RAMP1 Protein
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E. coli
His
50 µg/$411; 250 µg/$985; 10 µg/$276
RAMP1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
16.99 kDa
20 µg/$150
Viewing 1-5 of 5 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).