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RALB

v-ral simian leukemia viral oncogene homolog B

Multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Accomplishes its multiple functions by interacting with distinct downstream effectors. Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles. Required both to stabilize the assembly of the exocyst complex and to localize functional exocyst complexes to the leading edge of migrating cells. Plays a role in the late stages of cytokinesis and is required for the abscission of the bridge joining the sister cells emerging from mitosis. Required for suppression of apoptosis.

Gene Name: v-ral simian leukemia viral oncogene homolog B
Family/Subfamily: Ras GTPase superfamily IPR001806 , not assigned-Ras GTPase superfamily IPR001806
Synonyms: RALB, GTP binding protein), RAS-like protein B, Ras-related protein Ral-B
Target Sequences: NM_002881 NP_002872.1 P11234

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Products
Proteins (8)
Over-Expression Lysate (2)
Recombinant (6)
RALB (8)
No (8)
GST (2)
GST, N-terminus (2)
His (1)
Myc-DDK (Flag) (3)
Human (7)
293T Cells (1)
E. coli (2)
HEK 293 Cells (2)
Wheat Germ Extract (3)
Purified (4)
RALB Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
23.2 kDa
100 µg/$494
RALB Protein - 12.5% SDS-PAGE of human RALB stained with Coomassie Blue
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Wheat Germ Extract
GST
48.4 kDa
10 µg/$479; 25 µg/$670
RALB Protein - 12.5% SDS-PAGE of human RALB stained with Coomassie Blue
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Wheat Germ Extract
GST
49.8 kDa
10 µg/$479; 25 µg/$670
RALB Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
RALB Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
GST, N-terminus
1 mg/$1,355; 100 µg/$420; 20 µg/$323
RALB Protein - Purified recombinant protein RALB was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
23.2 kDa
20 µg/$1,107
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293T Cells
Myc-DDK (Flag)
23.2 kDa
20 µg/$150
RALB Protein
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E. coli
His
50 µg/$411; 250 µg/$985; 10 µg/$276
Viewing 1-8 of 8 product results


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Products: Proteins


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).