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Unfortunately, the antibody (ID:158662) is no longer available.

Below is a list of antibodies to the same protein target. You may also try your search again using the search box at the top of the page. Please contact us if you have any questions.



RAG2 / RAG-2

recombination activating gene 2

Core component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T-lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. DNA cleavage by the RAG complex occurs in 2 steps: a first nick is introduced in the top strand immediately upstream of the heptamer, generating a 3'-hydroxyl group that can attack the phosphodiester bond on the opposite strand in a direct transesterification reaction, thereby creating 4 DNA ends: 2 hairpin coding ends and 2 blunt, 5'-phosphorylated ends. The chromatin structure plays an essential role in the V(D)J recombination reactions and the presence of histone H3 trimethylated at 'Lys-4' (H3K4me3) stimulates both the nicking and haipinning steps. The RAG complex also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and monospecific recognition by the B-cell antigen receptor (BCR) expressed on individual B-lymphocytes. The introduction of DNA breaks by the RAG complex on one immunoglobulin allele induces ATM-dependent repositioning of the other allele to pericentromeric heterochromatin, preventing accessibility to the RAG complex and recombination of the second allele. In the RAG complex, RAG2 is not the catalytic component but is required for all known catalytic activities mediated by RAG1. It probably acts as a sensor of chromatin state that recruits the RAG complex to H3K4me3.

Gene Name: recombination activating gene 2
Synonyms: RAG2, RAG-2
Target Sequences: M94633 AAH22397.1 P55895

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Target Reactivity Applications Host Isotype Clonality Clone Format Epitope Publications Type
RAG2 / RAG-2 Rabbit IgG Polyclonal Unconjugated Human IHC-P, ICC, WB aa271-527 No Primary
Anti-RAG2 / RAG-2 Antibody (aa271-527) LS-C186092
Immunohistochemistry Image
Immunocytochemistry Image
Rabbit Polyclonal (IgG) to Human RAG2 / RAG-2
Human
IHC - Paraffin, ICC, Western blot
Unconjugated
RAG2 / RAG-2 Rabbit IgG Polyclonal Unconjugated Human, Mouse, Rat IHC-P, WB aa498-527 No Primary
Anti-RAG2 / RAG-2 Antibody (aa498-527) LS-C408005
Immunohistochemistry Image
Immunohistochemistry Image
Rabbit Polyclonal (IgG) to Human RAG2 / RAG-2
Human, Mouse, Rat
IHC - Paraffin, Western blot
Unconjugated
RAG2 / RAG-2 Rabbit IgG Polyclonal HRP Conjugated, Azide-free Human, Mouse IHC, WB, Flo, ELISA aa348-377 No Primary
Anti-RAG2 / RAG-2 Antibody (aa348-377, Azide-free, HRP) LS-C284962
Rabbit Polyclonal (IgG) to Human RAG2 / RAG-2
Human, Mouse
IHC, Western blot, Flow Cytometry, ELISA
HRP Conjugated, Azide-free
RAG2 / RAG-2 Rabbit IgG Polyclonal PE Conjugated Human, Mouse IHC, WB, Flo, ELISA aa348-377 No Primary
Anti-RAG2 / RAG-2 Antibody (aa348-377, PE) LS-C284963
Rabbit Polyclonal (IgG) to Human RAG2 / RAG-2
Human, Mouse
IHC, Western blot, Flow Cytometry, ELISA
PE Conjugated
RAG2 / RAG-2 Rabbit IgG Polyclonal Unconjugated Human, Mouse IHC, WB, Flo, ELISA aa348-377 No Primary
Anti-RAG2 / RAG-2 Antibody (aa348-377) LS-C324510
Rabbit Polyclonal (IgG) to Human RAG2 / RAG-2
Human, Mouse
IHC, Western blot, Flow Cytometry, ELISA
Unconjugated
RAG2 / RAG-2 Rabbit IgG Polyclonal FITC Conjugated Human, Mouse IHC, WB, Flo, ELISA aa348-377 No Primary
Anti-RAG2 / RAG-2 Antibody (aa348-377, FITC) LS-C284961
Rabbit Polyclonal (IgG) to Human RAG2 / RAG-2
Human, Mouse
IHC, Western blot, Flow Cytometry, ELISA
FITC Conjugated
RAG2 / RAG-2 Rabbit IgG Polyclonal AP Conjugated Human, Mouse IHC, WB, Flo, ELISA aa348-377 No Primary
Anti-RAG2 / RAG-2 Antibody (aa348-377, AP) LS-C284958
Rabbit Polyclonal (IgG) to Human RAG2 / RAG-2
Human, Mouse
IHC, Western blot, Flow Cytometry, ELISA
AP Conjugated
RAG2 / RAG-2 Rabbit IgG Polyclonal APC Conjugated Human, Mouse IHC, WB, Flo, ELISA aa348-377 No Primary
Anti-RAG2 / RAG-2 Antibody (aa348-377, APC) LS-C284959
Rabbit Polyclonal (IgG) to Human RAG2 / RAG-2
Human, Mouse
IHC, Western blot, Flow Cytometry, ELISA
APC Conjugated
RAG2 / RAG-2 Rabbit IgG Polyclonal Biotin Conjugated Human, Mouse IHC, WB, Flo, ELISA aa348-377 No Primary
Anti-RAG2 / RAG-2 Antibody (aa348-377, Biotin) LS-C284960
Rabbit Polyclonal (IgG) to Human RAG2 / RAG-2
Human, Mouse
IHC, Western blot, Flow Cytometry, ELISA
Biotin Conjugated
RAG2 / RAG-2 Mouse IgG2b,k Monoclonal 2G8 Unconjugated Human, Rat WB, ELISA No Primary
Anti-RAG2 / RAG-2 Antibody (clone 2G8) LS-C198057
Western blot Image
Enzyme-Linked Immunosorbent Assay Image
Mouse Monoclonal [clone 2G8] (IgG2b,k) to Human RAG2 / RAG-2
Human, Rat
Western blot, ELISA
Unconjugated
RAG2 / RAG-2 Rabbit IgG Polyclonal Unconjugated Human, Mouse, Rat IF, WB No Primary
Anti-RAG2 / RAG-2 Antibody LS-C334173
Immunofluorescence Image
Western blot Image
Rabbit Polyclonal (IgG) to Human RAG2 / RAG-2
Human, Mouse, Rat
Immunofluorescence, Western blot
Unconjugated
RAG2 / RAG-2 Rabbit Polyclonal Unconjugated Human, Bovine, Dog, Pig WB C-Terminus No Primary
Anti-RAG2 / RAG-2 Antibody (C-Terminus) LS-C145992
Western blot Image
Rabbit Polyclonal to Human RAG2 / RAG-2
Human, Bovine, Dog, Pig
Western blot
Unconjugated
RAG2 / RAG-2 Rabbit Polyclonal Unconjugated Human, Mouse, Rat ICC, IF, WB No Primary
Anti-RAG2 / RAG-2 Antibody LS-C482475
Immunofluorescence Image
Western blot Image
Rabbit Polyclonal to Human RAG2 / RAG-2
Human, Mouse, Rat
ICC, Immunofluorescence, Western blot
Unconjugated
RAG2 / RAG-2 Rabbit Polyclonal Unconjugated Human, Mouse, Rat IF, WB No Primary
Anti-RAG2 / RAG-2 Antibody LS-C341675
Rabbit Polyclonal to Human RAG2 / RAG-2
Human, Mouse, Rat
Immunofluorescence, Western blot
Unconjugated
RAG2 / RAG-2 Mouse IgG1 Monoclonal 4D5 Unconjugated Human WB, ELISA No Primary
Anti-RAG2 / RAG-2 Antibody (clone 4D5) LS-C109145
Western blot Image
Mouse Monoclonal [clone 4D5] (IgG1) to Human RAG2 / RAG-2
Human
Western blot, ELISA
Unconjugated
RAG2 / RAG-2 Rabbit Polyclonal FITC Conjugated Human, Gibbon, Bovine, Dog, Pig WB C-Terminus No Primary
Anti-RAG2 / RAG-2 Antibody (C-Terminus, FITC) LS-C468306
Western blot Image
Rabbit Polyclonal to Human RAG2 / RAG-2
Human, Gibbon, Bovine, Dog, Pig
Western blot
FITC Conjugated
RAG2 / RAG-2 Rabbit Polyclonal HRP Conjugated Human, Gibbon, Bovine, Dog, Pig WB C-Terminus No Primary
Anti-RAG2 / RAG-2 Antibody (C-Terminus, HRP) LS-C468307
Western blot Image
Rabbit Polyclonal to Human RAG2 / RAG-2
Human, Gibbon, Bovine, Dog, Pig
Western blot
HRP Conjugated
RAG2 / RAG-2 Rabbit Polyclonal Biotin Conjugated Human, Gibbon, Bovine, Dog, Pig WB C-Terminus No Primary
Anti-RAG2 / RAG-2 Antibody (C-Terminus, Biotin) LS-C468305
Western blot Image
Rabbit Polyclonal to Human RAG2 / RAG-2
Human, Gibbon, Bovine, Dog, Pig
Western blot
Biotin Conjugated
RAG2 / RAG-2 Rabbit IgG Polyclonal Unconjugated Zebrafish ELISA C-Terminus No Primary
Anti-RAG2 / RAG-2 Antibody (C-Terminus) LS-C210174
Rabbit Polyclonal (IgG) to Zebrafish RAG2 / RAG-2
Zebrafish
ELISA
Unconjugated
RAG2 / RAG-2 Rabbit IgG Polyclonal Unconjugated Zebrafish ELISA Internal No Primary
Anti-RAG2 / RAG-2 Antibody (Internal) LS-C210176
Rabbit Polyclonal (IgG) to Zebrafish RAG2 / RAG-2
Zebrafish
ELISA
Unconjugated
Target Corresponding Antibodies
RAG2 / RAG-2
RAG2 / RAG-2 Blocking Peptide - LS-E1680
LS-E1680
RAG2 / RAG-2
RAG2 / RAG-2
RAG2 / RAG-2 Antibody Blocking Peptide - LS-E22349
LS-E22349
RAG2 / RAG-2
LS-C145992
Type Target Reactivity Sample Type
Sandwich RAG2 / RAG-2 Human Cell Culture Supernatants, Serum, Tissue Homogenates, Plasma
Human RAG2 / RAG-2 ELISA Kit (Sandwich ELISA) - LS-F12467
 Image
 Image
Quantitative Sandwich ELISA
96-Well Strip Plate
Human
0.312-20 ng/ml
Cell Culture Supernatants, Serum, Tissue Homogenates, Plasma
Sandwich (Custom) RAG2 / RAG-2 Chicken
Chicken RAG2 / RAG-2 ELISA Kit (Sandwich ELISA) (Custom) - LS-F17979
 Image
 Image
Sandwich ELISA
96-Well Strip Plate
Chicken
Sandwich (Custom) RAG2 / RAG-2 Mouse
Mouse RAG2 / RAG-2 ELISA Kit (Sandwich ELISA) (Custom) - LS-F17981
 Image
 Image
Sandwich ELISA
96-Well Strip Plate
Mouse
Type Target Tag Species Source Purified Biological Activity Known Endotoxin Level Animal-Free
Recombinant RAG2 / RAG-2 GST Human Wheat
Human RAG2 / RAG-2 Recombinant (GST) Protein - LS-G30099
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image
Wheat Wheat Germ Extract
GST
Unpurified / Lyophilized

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).


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