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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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RAD51B

RAD51 paralog B

Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents. May promote the assembly of presynaptic RAD51 nucleoprotein filaments. Binds single-stranded DNA and double-stranded DNA and has DNA-dependent ATPase activity. Part of the RAD21 paralog protein complex BCDX2 which acts in the BRCA1-BRCA2-dependent HR pathway. Upon DNA damage, BCDX2 acts downstream of BRCA2 recruitment and upstream of RAD51 recruitment. BCDX2 binds predominantly to the intersection of the four duplex arms of the Holliday junction and to junction of replication forks. The BCDX2 complex was originally reported to bind single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA. The BCDX2 subcomplex RAD51B:RAD51C exhibits single-stranded DNA-dependent ATPase activity suggesting an involvement in early stages of the HR pathway.

Gene Name: RAD51 paralog B
Synonyms: RAD51B, HREC2, RAD51-like 1 (S. cerevisiae), RAD51L1, RAD51-like protein 1, Recombination repair protein, REC2, RecA-like protein, R51H2, RAD51 (S. cerevisiae)-like 1, RAD51 homolog B
Target Sequences: NM_002877 NP_002868.1 O15315

Publications (1)

1
Dysfunctional homologous recombination mediates genomic instability and progression in myeloma. Shammas MA, Shmookler Reis RJ, Koley H, Batchu RB, Li C, Munshi NC. Blood. 2009 113:2290-7. [PubMed:19050310] [PMC:PMC2652372]

Viewing 1-24 of 24 items
RAD51B Antibody - Anti-RAD51B antibody IHC staining of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Human RAD51B
Rabbit, Dog, Guinea pig, Human, Monkey
IHC, IHC-P, WB
Unconjugated
100µl   $485.00
RAD51B Antibody - Anti-RAD51B antibody IHC staining of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Human RAD51B
Rabbit, Dog, Guinea pig, Human, Monkey, Chimpanzee, Gibbon
IHC, IHC-P, WB
HRP Conjugated
100µl   0.65mg/ml   $405.00
RAD51B Antibody - Anti-RAD51B antibody IHC staining of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Human RAD51B
Rabbit, Dog, Guinea pig, Human, Monkey, Chimpanzee, Gibbon
IHC, IHC-P, WB
Biotin Conjugated
100µl   1mg/ml   $405.00
RAD51B Antibody - Anti-RAD51B antibody IHC staining of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Human RAD51B
Rabbit, Dog, Guinea pig, Human, Monkey, Chimpanzee, Gibbon
IHC, IHC-P, WB
FITC Conjugated
100µl   1mg/ml   $405.00
RAD51B Antibody - Anti-RAD51L1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY RAD51L1.
Select
Mouse Monoclonal [clone OTI7H4] (IgG1) to Human RAD51B
Human
Flo, IF, WB
Unconjugated
100µl   0.27mg/ml   $345.00
RAD51B Antibody - Anti-RAD51L1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY RAD51L1.
Select
Mouse Monoclonal [clone OTI7H4] (IgG1) to Human RAD51B
Human
Flo, IF, WB
Unconjugated, Carrier-free
100µg   $395.00
RAD51B Antibody - Immunohistochemistry analysis of paraffin-embedded human pancreas tissue, using RAD51L1 Antibody. The picture on the right is blocked with the synthesized peptide.
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Rabbit Polyclonal (IgG) to Human RAD51B
Mouse, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50µl   1mg/ml   $265.00; 100µl   1mg/ml   $325.00
RAD51B Antibody - Rad51L1 Antibody (1 H3/13) - Western blot of Rad51L1 expression in 1) HeLa, 2) HepG2 and 3) Cos 7 whole cell lysates.
Select
Mouse Monoclonal [clone 1 H3/13] to Human RAD51B
Human, Primate
WB
Unconjugated
100µl   $335.00
RAD51B Antibody
Select
Rabbit Polyclonal (IgG) to Human RAD51B
Mouse, Human, Monkey
ELISA, IF, IHC, WB
Unconjugated
100µl   1mg/ml   $325.00; 200µl   1mg/ml   $375.00
Select
Rabbit Polyclonal to Human RAD51B
Human
IF, IHC, WB
Unconjugated
100µl   $385.00
RAD51B Antibody - Immunofluorescence analysis of GFP-RNF168 trangenic U2OS cells.
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Rabbit Polyclonal (IgG) to Human RAD51B
Mouse, Rat
IF, IHC, WB
Unconjugated
50µl   $235.00; 100µl   $315.00; 200µl   $425.00
Select
Rabbit Polyclonal (IgG) to Human RAD51B
Mouse, Human, Monkey
ELISA, IHC, WB
Unconjugated
50µl   1mg/ml   $235.00; 100µl   1mg/ml   $265.00; 200µl   1mg/ml   $335.00
RAD51B Antibody - Peptide - + Immunohistochemistry analysis of paraffin-embedded human pancreas tissue using RAD51L1 antibody.
Select
Rabbit Polyclonal (IgG) to Human RAD51B
Mouse, Human
ELISA, IHC, WB
Unconjugated
100µg   $305.00
RAD51B Antibody - IHC of Rad51B (G226) pAb in paraffin-embedded human pancreas tissue.
Select
Rabbit Polyclonal to Human RAD51B
Mouse, Human
IHC, IHC-P, WB
Unconjugated
100µl   $345.00
Select
Rabbit Polyclonal (IgG) to Human RAD51B
Human
ELISA, WB
Unconjugated
100µg   $355.00
Select
Rabbit Polyclonal (IgG) to Human RAD51B
Human
IF
Unconjugated
50µl   $235.00; 100µl   $295.00; 200µl   $385.00
Select
Mouse Monoclonal (IgG) to Human RAD51B
Human
ELISA
Unconjugated
100µl   $530.00
Select
Rabbit Polyclonal (IgG) to Mouse RAD51B
Mouse, Rat
WB
Unconjugated
60µl   1mg/ml   $235.00; 120µl   1mg/ml   $295.00; 200µl   1mg/ml   $395.00
Select
Rabbit Polyclonal (IgG) to Human RAD51B
Mouse, Human
WB
Unconjugated
50µl   $235.00; 100µl   $295.00; 200µl   $385.00
RAD51B Antibody - RAD51L1 antibody Western blot of COLO205 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Human RAD51B
Mouse, Bovine, Human, Monkey
WB
Unconjugated
100µl   0.5mg/ml   $365.00
RAD51B Antibody - RAD51L1 antibody Western blot of COLO205 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Human RAD51B
Mouse, Bovine, Human, Monkey, Chimpanzee
WB
HRP Conjugated
100µl   0.65mg/ml   $385.00
RAD51B Antibody - RAD51L1 antibody Western blot of COLO205 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Human RAD51B
Mouse, Bovine, Human, Monkey, Chimpanzee
WB
Biotin Conjugated
100µl   1mg/ml   $385.00
RAD51B Antibody - RAD51L1 antibody Western blot of COLO205 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Human RAD51B
Mouse, Bovine, Human, Monkey, Chimpanzee
WB
FITC Conjugated
100µl   1mg/ml   $385.00
Select
Goat Polyclonal to Human RAD51B
Human, Monkey
Peptide-ELISA
Unconjugated
100µg   0.5mg/ml   $335.00

Viewing 1-24 of 24 items


If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).