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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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RAD21

RAD21 homolog (S. pombe)

Cleavable component of the cohesin complex, involved in chromosome cohesion during cell cycle, in DNA repair, and in apoptosis. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At metaphase-anaphase transition, this protein is cleaved by separase/ESPL1 and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis. Also plays a role in apoptosis, via its cleavage by caspase-3/CASP3 or caspase-7/CASP7 during early steps of apoptosis: the C-terminal 64 kDa cleavage product may act as a nuclear signal to initiate cytoplasmic events involved in the apoptotic pathway.

Gene Name: RAD21 homolog (S. pombe)
Synonyms: RAD21, CDLS4, HR21, KIAA0078, HHR21, NXP-1, NXP1, RAD21 (S. pombe) homolog, MCD1, Nuclear matrix protein 1, RAD21 homolog (S. pombe), HRAD21, SCC1, SCC1 homolog
Target Sequences: NM_006265 NP_006256.1 O60216

Filtered By: None
Target
RAD21 (30)
Reactivity
Human (30)
Mouse (26)
Rat (15)
Bat (8)
Bovine (10)
Chicken (9)
Chimpanzee (3)
Dog (9)
Gibbon (6)
Guinea pig (8)
Horse (9)
Monkey (10)
Orangutan (6)
Pig (8)
Rabbit (9)
Xenopus (4)
Zebrafish (1)
Application
IHC (13)
IHC-P (8)
WB (30)
Flo (1)
ELISA (5)
ICC (1)
IF (4)
IP (4)
Peptide-ELISA (2)
PLA (1)
Host
rabbit (22)
mouse (8)
Isotype
Ig (1)
IgG (6)
IgG1 (1)
IgG1,k (7)
Clonality
monoclonal mc (8)
polyclonal pc (22)
Clone
1B6D1 (1)
CM110-2C10 (6)
Format
Biotin Conjugated (3)
DY488 Conjugated (1)
DY550 Conjugated (1)
DY650 Conjugated (1)
FITC Conjugated (2)
HRP Conjugated (2)
Unconjugated (20)
Epitope
C-Terminus (8)
aa178-227 (4)
aa373-422 (4)
Internal (2)
490-570 aa, C-terminal (1)
Asp548 (1)
N-Terminus (1)
aa499-548 (1)
aa521-570 (1)
aa544-631 (1)
Publications
No (30)
Showing 1-25 of 30 results

RAD21 Antibody (aa544-631, clone CM110-2C10) IHC-plus™ LS-B82
Mouse Monoclonal [clone CM110-2C10] (IgG1,k) to Human RAD21
Mouse, Human
IHC IHC-P WB
Unconjugated
100µl 1mg/ml  $425.00
Anti-RAD21 antibody IHC of human adrenal medulla. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-RAD21 antibody IHC of human adrenal medulla. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

RAD21 Antibody (C-Terminus, clone CM110-2C10, Biotin) LS-C141126
Mouse Monoclonal [clone CM110-2C10] (IgG1,k) to Human RAD21
Mouse, Human
IHC IHC-P WB
Biotin Conjugated
100µl  $365.00
Anti-RAD21 antibody IHC of human adrenal medulla. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Cohesin detected in HeLa cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-RAD21 antibody IHC of human adrenal medulla. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Cohesin detected in HeLa cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

RAD21 Antibody (C-Terminus, clone CM110-2C10, DY550) LS-C141130
Mouse Monoclonal [clone CM110-2C10] (IgG1,k) to Human RAD21
Mouse, Human
IHC IHC-P WB
DY550 Conjugated
100µl  $365.00
Anti-RAD21 antibody IHC of human adrenal medulla. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Cohesin detected in HeLa cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-RAD21 antibody IHC of human adrenal medulla. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Cohesin detected in HeLa cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

RAD21 Antibody (C-Terminus, clone CM110-2C10, DY488) LS-C141128
Mouse Monoclonal [clone CM110-2C10] (IgG1,k) to Human RAD21
Mouse, Human
IHC IHC-P WB
DY488 Conjugated
100µl  $365.00
Anti-RAD21 antibody IHC of human adrenal medulla. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Cohesin detected in HeLa cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-RAD21 antibody IHC of human adrenal medulla. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Cohesin detected in HeLa cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

RAD21 Antibody (C-Terminus, clone CM110-2C10, DY650) LS-C141127
Mouse Monoclonal [clone CM110-2C10] (IgG1,k) to Human RAD21
Mouse, Human
IHC IHC-P WB
DY650 Conjugated
100µl  $365.00
Anti-RAD21 antibody IHC of human adrenal medulla. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Cohesin detected in HeLa cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-RAD21 antibody IHC of human adrenal medulla. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Cohesin detected in HeLa cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

RAD21 Antibody (clone 1B6D1) LS-C669423
Mouse Monoclonal [clone 1B6D1] (IgG1) to Human RAD21
Human
ELISA Flo IF IHC WB
Unconjugated
0.1mg  $365.00

RAD21 Antibody (C-Terminus) LS-C368680
Rabbit Polyclonal to Human RAD21
Zebrafish, Rat, Mouse, Bovine, Human
ICC IF IHC IHC-P WB
Unconjugated
30µl 1mg/ml  $205.00; 100µl 1mg/ml  $245.00; 200µl 1mg/ml  $305.00
Immunohistochemical analysis of RAD21 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected with HRP and DAB as chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Immunofluorescent analysis of RAD21 staining in Jurkat cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 deg C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).
Immunohistochemical analysis of RAD21 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected with HRP and DAB as chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Immunofluorescent analysis of RAD21 staining in Jurkat cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 deg C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).

RAD21 Antibody (aa521-570) IHC-plus™ LS-B9251
Rabbit Polyclonal (IgG) to Human RAD21
Mouse, Human
IHC IHC-P Peptide-ELISA WB
Unconjugated
50µl 1mg/ml  $425.00
Anti-RAD21 antibody IHC staining of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Western blot analysis of lysates from Jurkat cells, using RAD21 Antibody. The lane on the right is blocked with the synthesized peptide.
Anti-RAD21 antibody IHC staining of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Western blot analysis of lysates from Jurkat cells, using RAD21 Antibody. The lane on the right is blocked with the synthesized peptide.

RAD21 Antibody (aa499-548) IHC-plus™ LS-B14690
Rabbit Polyclonal (IgG) to Human RAD21
Mouse, Human
IHC IHC-P Peptide-ELISA WB
Unconjugated
50µl 1mg/ml  $425.00
Human Breast: Formalin-Fixed, Paraffin-Embedded (FFPE)
Western blot analysis of the lysates from HUVECcells using RAD21 antibody.
Human Breast: Formalin-Fixed, Paraffin-Embedded (FFPE)
Western blot analysis of the lysates from HUVECcells using RAD21 antibody.

RAD21 Antibody (490-570 aa, C-terminal) LS-C385727
Rabbit Polyclonal (IgG) to Human RAD21
Mouse, Human
ELISA IF IHC WB
Unconjugated
100µl 1mg/ml  $265.00

RAD21 Antibody (Internal) LS-C153438
Rabbit Polyclonal to Human RAD21
Human
ELISA IHC WB
Unconjugated
100µg 100µl 1mg/ml  $315.00

RAD21 Antibody LS-C131786
Rabbit Polyclonal (IgG) to Human RAD21
Mouse, Rat, Human, Monkey
IF IP WB
Unconjugated
100µl  $530.00

RAD21 Antibody (Internal) LS-C144918
Rabbit Polyclonal to Human RAD21
Human
IHC WB
Unconjugated
100µl  $365.00

RAD21 Antibody (Asp548) LS-C192027
Rabbit Polyclonal to Human RAD21
Mouse, Human
IHC WB
Unconjugated
100µl  $345.00

RAD21 Antibody (C-Terminus) LS-C46992
Rabbit Polyclonal to Human RAD21
Mouse, Rat, Human
ELISA WB
Unconjugated
100µg 0.5mg/ml  $315.00

RAD21 Antibody (C-Terminus) LS-C287016
Rabbit Polyclonal (IgG) to Human RAD21
Chicken, Bovine, Rabbit, Mouse, Dog, Rat, Horse, Human
IP PLA WB
Unconjugated
100µl 1mg/ml  $395.00
Detection of Human and Mouse Rad21 by Western Blot. Samples: Whole cell lysate from HeLa (5, 15 and 50 ug), 293T (T; 50 ug) and mouse NIH3T3 (M; 50 ug) cells. Antibodies: Affinity purified rabbit anti-Rad21 antibody used for WB at 0.2 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.
Detection of Human and Mouse Rad21 by Western Blot. Samples: Whole cell lysate from HeLa (5, 15 and 50 ug), 293T (T; 50 ug) and mouse NIH3T3 (M; 50 ug) cells. Antibodies: Affinity purified rabbit anti-Rad21 antibody used for WB at 0.2 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.

RAD21 Antibody (C-Terminus) LS-C757604
Rabbit Polyclonal (Ig) to Human RAD21
Mouse, Rat, Human
ELISA WB
Unconjugated
50µl  $215.00; 200µl  $325.00
All lanes: Anti-RAD21 Antibody (C-Term) at 1:2000 dilution Lane 1: Hela whole cell lysate Lane 2: 293 whole cell lysate Lane 3: A431 whole cell lysate Lane 4: C2C12 whole cell lysate Lane 5: C6 whole cell lysate Lane 6: H-4-II-E whole cell lysate Lane 7: MOLT-4 whole cell lysate Lane 8: NIH/3T3 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size: 72 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
All lanes: Anti-RAD21 Antibody (C-Term) at 1:2000 dilution Lane 1: Hela whole cell lysate Lane 2: 293 whole cell lysate Lane 3: A431 whole cell lysate Lane 4: C2C12 whole cell lysate Lane 5: C6 whole cell lysate Lane 6: H-4-II-E whole cell lysate Lane 7: MOLT-4 whole cell lysate Lane 8: NIH/3T3 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size: 72 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

RAD21 Antibody (clone CM110-2C10) LS-C179726
Mouse Monoclonal [clone CM110-2C10] (IgG1,k) to Human RAD21
Mouse, Rat, Human
IP WB
Unconjugated
100µg 1mg/ml  $350.00
Immunoprecipitation Image
Immunoprecipitation Image

RAD21 Antibody LS-C131785
Rabbit Polyclonal (IgG) to Human RAD21
Mouse, Rat, Human, Monkey
IP WB
Unconjugated
100µl  $530.00

RAD21 Antibody (N-Terminus) LS-C79482
Mouse Monoclonal (IgG1,k) to Human RAD21
Mouse, Human
WB
Unconjugated
100µl  $515.00

RAD21 Antibody LS-C658857
Rabbit Polyclonal to Human RAD21
Mouse, Human
WB
Unconjugated
100µl  $305.00

RAD21 Antibody LS-C394183
Rabbit Polyclonal to Human RAD21
Human
WB
Unconjugated
100µl  $305.00
All lanes: Anti-RAD21 Antibody at 1:1000 dilution. Lane 1: HeLa whole cell lysate. Lane 2: K562 whole cell lysate Lysates/proteins at 20 ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1:10000 dilution. Predicted band size: 72 kDa. Blocking/Dilution buffer: 5% NFDM/TBST.
All lanes: Anti-RAD21 Antibody at 1:1000 dilution. Lane 1: HeLa whole cell lysate. Lane 2: K562 whole cell lysate Lysates/proteins at 20 ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1:10000 dilution. Predicted band size: 72 kDa. Blocking/Dilution buffer: 5% NFDM/TBST.

RAD21 Antibody (aa178-227) LS-C135398
Rabbit Polyclonal to Rat RAD21
Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Rat, Pig, Horse, Bat, Human, Monkey
WB
Unconjugated
50µg  $365.00
RAD21 antibody Western blot of Rat Heart lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
RAD21 antibody Western blot of Rat Heart lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

RAD21 Antibody (aa178-227, FITC) LS-C462263
Rabbit Polyclonal to Rat RAD21
Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Rat, Pig, Horse, Bat, Gibbon, Orangutan, Human, Monkey
WB
FITC Conjugated
100µl 1mg/ml  $385.00
RAD21 antibody Western blot of Rat Heart lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
RAD21 antibody Western blot of Rat Heart lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

RAD21 Antibody (aa373-422) LS-C135399
Rabbit Polyclonal to Rat RAD21
Xenopus, Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Bat, Rat, Pig, Horse, Human, Monkey
WB
Unconjugated
50µg  $365.00
RAD21 antibody Western blot of Rat Heart lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
RAD21 antibody Western blot of Rat Heart lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Showing 1-25 of 30 results

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PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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