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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Cell Cycle Pathways
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RAD1

RAD1 homolog (S. pombe)

Component of the 9-1-1 cell-cycle checkpoint response complex that plays a major role in DNA repair. The 9-1-1 complex is recruited to DNA lesion upon damage by the RAD17-replication factor C (RFC) clamp loader complex. Acts then as a sliding clamp platform on DNA for several proteins involved in long-patch base excision repair (LP-BER). The 9-1-1 complex stimulates DNA polymerase beta (POLB) activity by increasing its affinity for the 3'-OH end of the primer-template and stabilizes POLB to those sites where LP-BER proceeds; endonuclease FEN1 cleavage activity on substrates with double, nick, or gap flaps of distinct sequences and lengths; and DNA ligase I (LIG1) on long-patch base excision repair substrates. The 9-1-1 complex is necessary for the recruitment of RHNO1 to sites of double-stranded breaks (DSB) occurring during the S phase. Isoform 1 possesses 3'->5' double stranded DNA exonuclease activity.

Gene Name: RAD1 homolog (S. pombe)
Synonyms: RAD1, DNA repair exonuclease REC1, RAD1 (S. pombe) homolog, REC1, RAD1 homolog (S. pombe), Exonuclease homolog RAD1, HRAD1
Target Sequences: NM_002853 NP_002844.1 O60671

Filtered by: None
Target
RAD1 (25)
Reactivity
Human (25)
Mouse (8)
Rat (4)
Bat (4)
Bovine (4)
Chimpanzee (3)
Dog (4)
Gibbon (3)
Guinea pig (4)
Hamster (4)
Horse (4)
Monkey (4)
Orangutan (3)
Pig (4)
Rabbit (4)
Application
IHC (6)
IHC-P (2)
WB (24)
ELISA (12)
IF (1)
IP (2)
RNAi (1)
Host
rabbit (23)
mouse (2)
Isotype
IgG (15)
IgG3,k (1)
Clonality
monoclonal mc (2)
polyclonal pc (23)
Clone
1G2 (1)
4126 (1)
Format
AP Conjugated (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Unconjugated (16)
Epitope
aa118-146 (8)
aa179-228 (4)
Internal (1)
N-Terminus (1)
aa1-282 (1)
aa77-282 (1)
Publications
No (25)
Showing 1-25 of 25 results

IHC-plus™ RAD1 Antibody (N-Terminus, clone 4126) LS-B1706
Mouse Monoclonal [clone 4126] (IgG) to Human RAD1
Human
IHC, IHC-P, WB
Unconjugated
50µl 1mg/ml  $425.00
Anti-RAD1 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

RAD1 Antibody LS-C331221
Rabbit Polyclonal (IgG) to Human RAD1
Mouse, Human
IF, IHC, WB
Unconjugated
50µl  $235.00; 100µl  $315.00; 200µl  $425.00
Immunohistochemistry of paraffin-embedded rat brain tissue.
Immunohistochemistry of paraffin-embedded mouse brain tissue.

RAD1 Antibody (aa1-282) LS-C376431
Rabbit Polyclonal (IgG) to Human RAD1
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50µl  $285.00; 100µl  $385.00
Immunohistochemistry of paraffin-embedded human testicle using antibody at 1:100 dilution.
Western blot. All lanes: Cell cycle checkpoint protein RAD1 antibody at 6 ug/ml+NIH3T3 whole cell lysate. Secondary antibody: Goat polyclonal to rabbit at 1:10000 dilution. Predicted band size: 32 kDa. Observed band size: 32 kDa.

RAD1 Antibody LS-C753983
Rabbit Polyclonal (IgG) to Human RAD1
Human
ELISA, IHC, IP, WB
Unconjugated
100µg  $335.00

RAD1 Antibody (clone 1G2) LS-C133073
Mouse Monoclonal [clone 1G2] (IgG3,k) to Human RAD1
Human
ELISA, RNAi, WB
Unconjugated
100µg  $365.00
Western blot of RAD1 expression in transfected 293T cell line by RAD1 monoclonal antibody (M01), clone 1G2.
Detection limit for recombinant GST tagged RAD1 is approximately 0.3 ng/ml as a capture antibody.

RAD1 Antibody LS-C409062
Rabbit Polyclonal (IgG) to Human RAD1
Mouse, Rat, Human
IHC, IP, WB
Unconjugated
50µl  $235.00; 100µl  $295.00; 200µl  $385.00

RAD1 Antibody LS-C341454
Rabbit Polyclonal to Human RAD1
Mouse, Rat, Human
IHC, WB
Unconjugated
100µl 1mg/ml  $385.00

RAD1 Antibody (aa118-146) LS-C324498
Rabbit Polyclonal (IgG) to Human RAD1
Human
ELISA, WB
Unconjugated
200µl  $590.00

RAD1 Antibody (aa118-146, Biotin) LS-C239724
Rabbit Polyclonal (IgG) to Human RAD1
Human
ELISA, WB
Biotin Conjugated
200µl  $740.00

RAD1 Antibody (aa118-146, FITC) LS-C239725
Rabbit Polyclonal (IgG) to Human RAD1
Human
ELISA, WB
FITC Conjugated
200µl  $740.00

RAD1 Antibody (aa118-146, APC) LS-C239722
Rabbit Polyclonal (IgG) to Human RAD1
Human
ELISA, WB
APC Conjugated
200µl  $740.00

RAD1 Antibody (aa118-146, AP) LS-C239723
Rabbit Polyclonal (IgG) to Human RAD1
Human
ELISA, WB
AP Conjugated
200µl  $740.00

RAD1 Antibody (aa118-146, PE) LS-C239726
Rabbit Polyclonal (IgG) to Human RAD1
Human
ELISA, WB
PE Conjugated
200µl  $740.00

RAD1 Antibody (aa118-146, Azide-free, HRP) LS-C248608
Rabbit Polyclonal (IgG) to Human RAD1
Human
ELISA, WB
HRP Conjugated, Azide-free
200µl  $740.00

RAD1 Antibody LS-C778507
Rabbit Polyclonal to Human RAD1
Mouse, Human
ELISA, WB
Unconjugated
100µg 100µl 1mg/ml  $305.00

RAD1 Antibody LS-C809151
Rabbit Polyclonal (IgG) to Human RAD1
Mouse, Human
ELISA, WB
Unconjugated
100µl 1mg/ml  $325.00; 200µl 1mg/ml  $375.00
Western blot Image

RAD1 Antibody LS-C341061
Rabbit Polyclonal to Human RAD1
Mouse, Rat, Human
WB
Unconjugated
100µl 1mg/ml  $385.00

RAD1 Antibody (aa179-228) LS-C116743
Rabbit Polyclonal to Human RAD1
Rabbit, Dog, Guinea pig, Bovine, Hamster, Pig, Horse, Bat, Human, Monkey
WB
Unconjugated
100µl 0.5mg/ml  $365.00
RAD1 antibody Western blot of COLO205 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

RAD1 Antibody (aa179-228, HRP) LS-C463944
Rabbit Polyclonal to Human RAD1
Rabbit, Dog, Guinea pig, Bovine, Hamster, Pig, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey
WB
HRP Conjugated
100µl 0.65mg/ml  $385.00
RAD1 antibody Western blot of COLO205 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

RAD1 Antibody (aa179-228, Biotin) LS-C463942
Rabbit Polyclonal to Human RAD1
Rabbit, Dog, Guinea pig, Bovine, Hamster, Pig, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey
WB
Biotin Conjugated
100µl 1mg/ml  $385.00
RAD1 antibody Western blot of COLO205 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

RAD1 Antibody (aa179-228, FITC) LS-C463943
Rabbit Polyclonal to Human RAD1
Rabbit, Dog, Guinea pig, Bovine, Hamster, Pig, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey
WB
FITC Conjugated
100µl 1mg/ml  $385.00
RAD1 antibody Western blot of COLO205 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

RAD1 Antibody (Internal) LS-C353764
Rabbit Polyclonal to Human RAD1
Mouse, Rat, Human
WB
Unconjugated
100µl 1mg/ml  $245.00
Western blot analysis of RAD1 expression in A549 (A); Raw264.7 (B); H9C2 (C) whole cell lysates.

RAD1 Antibody LS-C709
Rabbit Polyclonal (IgG) to Human RAD1
Mouse, Human
WB
Unconjugated
100µg 200µl 0.5mg/ml  $335.00
The anti-Rad1 rabbit PcAb was diluted at 2 ug/ml (lane 1) and 1 ug/ml (lane 2) and tested against 10 ug of 293 cell lysate by western blotting. A single band at 66 kD is detected.

RAD1 Antibody (aa118-146) LS-C162404
Rabbit Polyclonal to Human RAD1
Human
WB
Unconjugated
400µl  $325.00
RAD1 Antibody western blot of K562 cell line lysates (35 ug/lane). The RAD1 antibody detected the RAD1 protein (arrow).

RAD1 Antibody (aa77-282) LS-C185338
Rabbit Polyclonal (IgG) to Human RAD1
Human
Unconjugated
100µl 4.6mg/ml  $245.00
Showing 1-25 of 25 results

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).