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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
Protein Family And Group
Infectious Disease
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RAD1

RAD1 homolog (S. pombe)

Component of the 9-1-1 cell-cycle checkpoint response complex that plays a major role in DNA repair. The 9-1-1 complex is recruited to DNA lesion upon damage by the RAD17-replication factor C (RFC) clamp loader complex. Acts then as a sliding clamp platform on DNA for several proteins involved in long-patch base excision repair (LP-BER). The 9-1-1 complex stimulates DNA polymerase beta (POLB) activity by increasing its affinity for the 3'-OH end of the primer-template and stabilizes POLB to those sites where LP-BER proceeds; endonuclease FEN1 cleavage activity on substrates with double, nick, or gap flaps of distinct sequences and lengths; and DNA ligase I (LIG1) on long-patch base excision repair substrates. The 9-1-1 complex is necessary for the recruitment of RHNO1 to sites of double-stranded breaks (DSB) occurring during the S phase. Isoform 1 possesses 3'->5' double stranded DNA exonuclease activity.

Gene Name: RAD1 homolog (S. pombe)
Synonyms: RAD1, DNA repair exonuclease REC1, RAD1 (S. pombe) homolog, REC1, RAD1 homolog (S. pombe), Exonuclease homolog RAD1, HRAD1
Target Sequences: NM_002853 NP_002844.1 O60671


RAD1 Antibody - Anti-RAD1 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Select
Mouse Monoclonal [clone 4126] (IgG) to Human RAD1
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$425
RAD1 Antibody - Peptide - + Immunohistochemistry analysis of paraffin-embedded human heart tissue using RAD antibody.
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Rabbit Polyclonal (IgG) to Human RAD1
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$305
RAD1 Antibody - Immunohistochemistry of paraffin-embedded rat brain tissue.
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Rabbit Polyclonal (IgG) to Human RAD1
Mouse, Human
IF, IHC, WB
Unconjugated
20 µl/$215; 50 µl/$235; 100 µl/$315; 200 µl/$425
RAD1 Antibody - Immunohistochemistry of paraffin-embedded human testicle using antibody at 1:100 dilution.
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Rabbit Polyclonal (IgG) to Human RAD1
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$285; 100 µl/$385
Select
Rabbit Polyclonal (IgG) to Human RAD1
Human
ELISA, IHC, IP, WB
Unconjugated
100 µg/$335
RAD1 Antibody - Western blot of RAD1 expression in transfected 293T cell line by RAD1 monoclonal antibody (M01), clone 1G2.
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Mouse Monoclonal [clone 1G2] (IgG3,k) to Human RAD1
Human
ELISA, RNAi, WB
Unconjugated
100 µg/$365
Select
Rabbit Polyclonal (IgG) to Human RAD1
Mouse, Rat, Human
IHC, IP, WB
Unconjugated
20 µl/$215; 50 µl/$235; 100 µl/$295; 200 µl/$385
RAD1 Antibody - Immunofluorescence staining of RAD1 in U2OS cells. Cells were fixed with 4% PFA, permeabilzed with 0.1% Triton X-100 in PBS, blocked with 10% serum, and incubated with rabbit anti-Human RAD1 polyclonal antibody (dilution ratio 1:200) at 4°C overnight. Then cells were stained with the Alexa Fluor 488-conjugated Goat Anti-rabbit IgG secondary antibody (green). Positive staining was localized to Nucleus.
Select
Rabbit Polyclonal (IgG) to Human RAD1
Human
ICC, IF
Unconjugated
50 µl/$235; 100 µl/$275; 200 µl/$305
Select
Rabbit Polyclonal to Human RAD1
Mouse, Rat, Human
IHC, WB
Unconjugated
100 µl/$385
Select
Rabbit Polyclonal (IgG) to Human RAD1
Human
ELISA, WB
Unconjugated
200 µl/$590
Select
Rabbit Polyclonal (IgG) to Human RAD1
Human
ELISA, WB
Biotin Conjugated
200 µl/$740
Select
Rabbit Polyclonal (IgG) to Human RAD1
Human
ELISA, WB
FITC Conjugated
200 µl/$740
Select
Rabbit Polyclonal (IgG) to Human RAD1
Human
ELISA, WB
APC Conjugated
200 µl/$740
Select
Rabbit Polyclonal (IgG) to Human RAD1
Human
ELISA, WB
AP Conjugated
200 µl/$740
Select
Rabbit Polyclonal (IgG) to Human RAD1
Human
ELISA, WB
PE Conjugated
200 µl/$740
Select
Rabbit Polyclonal (IgG) to Human RAD1
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$740
Select
Rabbit Polyclonal to Human RAD1
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$305
RAD1 Antibody - Western blot analysis of RAD1 expression in HeLa cells lysate. The lane on the left is treated with the antigen-specific peptide.
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Rabbit Polyclonal (IgG) to Human RAD1
Mouse, Human
ELISA, WB
Unconjugated
100 µl/$325; 200 µl/$375
Select
Rabbit Polyclonal to Human RAD1
Mouse, Rat, Human
WB
Unconjugated
100 µl/$385
RAD1 Antibody - Western blot analysis of RAD1 expression in A549 (A); Raw264.7 (B); H9C2 (C) whole cell lysates.
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Rabbit Polyclonal to Human RAD1
Mouse, Rat, Human
WB
Unconjugated
100 µl/$245
RAD1 Antibody - The anti-Rad1 rabbit PcAb was diluted at 2 ug/ml (lane 1) and 1 ug/ml (lane 2) and tested against 10 ug of 293 cell lysate by western blotting. A single band at 66 kD is detected.
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Rabbit Polyclonal (IgG) to Human RAD1
Mouse, Human
WB
Unconjugated
100 µg/$335
RAD1 Antibody - RAD1 antibody Western blot of COLO205 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Human RAD1
Rabbit, Dog, Guinea pig, Bovine, Hamster, Pig, Horse, Bat, Human, Monkey
WB
Unconjugated
100 µl/$365
RAD1 Antibody - RAD1 Antibody western blot of K562 cell line lysates (35 ug/lane). The RAD1 antibody detected the RAD1 protein (arrow).
Select
Rabbit Polyclonal to Human RAD1
Human
WB
Unconjugated
400 µl/$325
Select
Rabbit Polyclonal to Human RAD1
Mouse, Human
Unconjugated
100 µl/$305
Select
Rabbit Polyclonal (IgG) to Human RAD1
Human
Unconjugated
100 µl/$355
Viewing 1-25 of 28 products



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).