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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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RACGAP1 / MGCRACGAP

Rac GTPase activating protein 1

Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Required for proper attachment of the midbody to the cell membrane during cytokinesis. Plays key roles in controlling cell growth and differentiation of hematopoietic cells through mechanisms other than regulating Rac GTPase activity. Also involved in the regulation of growth-related processes in adipocytes and myoblasts. May be involved in regulating spermatogenesis and in the RACGAP1 pathway in neuronal proliferation. Shows strong GAP (GTPase activation) activity towards CDC42 and RAC1 and less towards RHOA. Essential for the early stages of embryogenesis. May play a role in regulating cortical activity through RHOA during cytokinesis. May participate in the regulation of sulfate transport in male germ cells.

Gene Name: Rac GTPase activating protein 1
Synonyms: RACGAP1, GTPase activating protein, ID-GAP, KIAA1478, MgcRacGAP, Protein CYK4 homolg, Male germ cell RacGap, CYK4, HsCYK-4
Target Sequences: NM_013277 NP_037409.2 Q9H0H5

Filtered by: None
Target
RACGAP1 / MGCRACGAP (67)
Reactivity
Human (66)
Mouse (24)
Rat (20)
Bat (9)
Bovine (13)
Chimpanzee (9)
Dog (9)
Gibbon (6)
Guinea pig (8)
Horse (9)
Monkey (14)
Orangutan (3)
Pig (5)
Rabbit (8)
Application
IHC (36)
IHC-P (9)
WB (60)
Flo (8)
ELISA (22)
ICC (9)
IF (27)
IP (5)
Peptide-ELISA (4)
Host
rabbit (54)
mouse (12)
goat (1)
Isotype
IgG (37)
IgG1 (9)
IgG2b (2)
IgG2b,k (1)
Clonality
monoclonal mc (12)
polyclonal pc (55)
Clone
1G6 (1)
OTI1C10 (2)
OTI3A5 (2)
OTI3D8 (2)
OTI4C5 (2)
OTI4H8 (2)
Format
AP Conjugated (1)
APC (1)
APC Conjugated (2)
Azide-free (1)
Biotin Conjugated (6)
Carrier-free (5)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (6)
HRP Conjugated (6)
PE Conjugated (2)
Unconjugated (42)
Epitope
aa123-238 (10)
aa106-539 (8)
aa23-50 (8)
C-Terminus (4)
aa179-228 (4)
aa20-69 (4)
330-410 aa (2)
pSer387 (2)
30-110 aa, N-terminal (1)
Internal (1)
Leu383 (1)
N-Terminus (1)
aa1-202 (1)
aa150-200 (1)
aa200-250 (1)
aa31-80 (1)
aa353-402 (1)
aa620-632 (1)
Publications
No (67)
Showing 1-25 of 67 results

IHC-plus™ RACGAP1 / MGCRACGAP Antibody (clone 1G6) LS-B15501
Mouse Monoclonal [clone 1G6] (IgG2b,k) to Human RACGAP1 / MGCRACGAP
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50µg  $425.00
Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE), at a concentration of 10 ug/ml.
Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE), at a concentration of 10 ug/ml.

RACGAP1 / MGCRACGAP Antibody (aa23-50) LS-C162403
Rabbit Polyclonal to Human RACGAP1 / MGCRACGAP
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
400µl  $325.00
RACGAP1 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human testis tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
Confocal immunofluorescence of RACGAP1 Antibody with MCF-7 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).

RACGAP1 / MGCRACGAP Antibody (phospho-Ser387) LS-C801233
Rabbit Polyclonal (IgG) to Human RACGAP1 / MGCRACGAP
Mouse, Rat, Human, Monkey
ELISA, IF, IHC, WB
Unconjugated
100µl 1mg/ml  $325.00; 200µl 1mg/ml  $375.00
Immunohistochemistry Image
Immunofluorescence Image

RACGAP1 / MGCRACGAP Antibody (aa23-50) LS-C324497
Rabbit Polyclonal (IgG) to Human RACGAP1 / MGCRACGAP
Human
ELISA, Flo, IF, IHC, WB
Unconjugated
200µl  $590.00

RACGAP1 / MGCRACGAP Antibody (aa23-50, Biotin) LS-C267739
Rabbit Polyclonal (IgG) to Human RACGAP1 / MGCRACGAP
Human
ELISA, Flo, ICC, IF, IHC, WB
Biotin Conjugated
200µl  $740.00

RACGAP1 / MGCRACGAP Antibody (aa23-50, FITC) LS-C267740
Rabbit Polyclonal (IgG) to Human RACGAP1 / MGCRACGAP
Human
ELISA, Flo, ICC, IF, IHC, WB
FITC Conjugated
200µl  $740.00

RACGAP1 / MGCRACGAP Antibody (aa23-50, AP) LS-C267737
Rabbit Polyclonal (IgG) to Human RACGAP1 / MGCRACGAP
Human
ELISA, Flo, ICC, IF, IHC, WB
AP Conjugated
200µl  $740.00

RACGAP1 / MGCRACGAP Antibody (aa23-50, APC) LS-C267738
Rabbit Polyclonal (IgG) to Human RACGAP1 / MGCRACGAP
Human
ELISA, Flo, ICC, IF, IHC, WB
APC Conjugated
200µl  $740.00

RACGAP1 / MGCRACGAP Antibody (aa23-50, Azide-free, HRP) LS-C267741
Rabbit Polyclonal (IgG) to Human RACGAP1 / MGCRACGAP
Human
ELISA, Flo, ICC, IF, IHC, WB
HRP Conjugated, Azide-free
200µl  $740.00

RACGAP1 / MGCRACGAP Antibody (aa23-50, PE) LS-C267742
Rabbit Polyclonal (IgG) to Human RACGAP1 / MGCRACGAP
Human
ELISA, Flo, ICC, IF, IHC, WB
PE Conjugated
200µl  $740.00

RACGAP1 / MGCRACGAP Antibody (N-Terminus) LS-C353415
Rabbit Polyclonal to Human RACGAP1 / MGCRACGAP
Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100µl 1mg/ml  $245.00
Immunohistochemical analysis of MGCRACGAP staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Immunofluorescent analysis of MGCRACGAP staining in K562 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).

RACGAP1 / MGCRACGAP Antibody (Internal) LS-C413051
Rabbit Polyclonal to Human RACGAP1 / MGCRACGAP
Mouse, Human, Monkey
ICC, IF, IHC, IHC-P, WB
Unconjugated
100µl 1mg/ml  $275.00
Immunohistochemical analysis of MGCRACGAP staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Immunofluorescent analysis of MGCRACGAP staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 deg C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).

RACGAP1 / MGCRACGAP Antibody (aa1-202) LS-C186293
Rabbit Polyclonal (IgG) to Human RACGAP1 / MGCRACGAP
Mouse, Human
ICC, IHC, IHC-P, WB
Unconjugated
100µl 1mg/ml  $355.00
IHC of paraffin-embedded H1299 xenograft using RACGAP1 antibody at 1:500 dilution.
IHC of paraffin-embedded Hepatoma using RACGAP1 antibody at 1:500 dilution.

RACGAP1 / MGCRACGAP Antibody (aa620-632) LS-C55354
Goat Polyclonal to Human RACGAP1 / MGCRACGAP
Dog, Bovine, Pig, Horse, Bat, Human, Monkey
IF, IHC, Peptide-ELISA, WB
Unconjugated
100µg 0.5mg/ml  $405.00
RACGAP1 / MGCRACGAP antibody (4µg/ml) staining of paraffin embedded Human Testis. Microwaved antigen retrieval with Tris/EDTA buffer pH9, HRP-staining.
RACGAP1 / MGCRACGAP antibody immunofluorescence analysis of paraformaldehyde fixed MCF7 cells, permeabilized with 0.15% Triton. Primary incubation 1hr (10ug/ml) followed by Alexa Fluor 488 secondary antibody (4ug/ml), showing nuclear staining. The nuclear stain is DAPI (blue). Negative control: Unimmunized goat IgG (10ug/ml) followed by Alexa Fluor 488 secondary antibody (2ug/ml).

RACGAP1 / MGCRACGAP Antibody LS-C806580
Rabbit Polyclonal (IgG) to Human RACGAP1 / MGCRACGAP
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100µl 1mg/ml  $325.00; 200µl 1mg/ml  $375.00
Immunohistochemistry Image
Immunofluorescence Image

RACGAP1 / MGCRACGAP Antibody LS-C333966
Rabbit Polyclonal (IgG) to Human RACGAP1 / MGCRACGAP
Mouse, Rat, Human
IF, IHC, IP, WB
Unconjugated
50µl  $265.00; 100µl  $345.00; 200µl  $495.00
Immunohistochemistry of paraffin-embedded human kidney cancer using RACGAP1 antibody at dilution of 1:200 (x400 lens).
Immunohistochemistry of paraffin-embedded human stomach using RACGAP1 antibody at dilution of 1:200 (x400 lens).

RACGAP1 / MGCRACGAP Antibody LS-C753611
Mouse Monoclonal (IgG1) to Human RACGAP1 / MGCRACGAP
Human
ELISA, IF, IHC, IP, WB
Unconjugated
100µg  $375.00

RACGAP1 / MGCRACGAP Antibody (330-410 aa) LS-C381524
Rabbit Polyclonal (IgG) to Human RACGAP1 / MGCRACGAP
Mouse, Rat, Human, Monkey
ELISA, IF, IHC, WB
Unconjugated
50µl 1mg/ml  $235.00; 100µl 1mg/ml  $265.00; 200µl 1mg/ml  $335.00

RACGAP1 / MGCRACGAP Antibody (30-110 aa, N-terminal) LS-C385726
Rabbit Polyclonal (IgG) to Human RACGAP1 / MGCRACGAP
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
50µl 1mg/ml  $235.00; 100µl 1mg/ml  $265.00; 200µl 1mg/ml  $335.00

RACGAP1 / MGCRACGAP Antibody (phospho-Ser387) LS-C199034
Rabbit Polyclonal (IgG) to Human RACGAP1 / MGCRACGAP
Mouse, Rat, Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50µl 1mg/ml  $265.00; 100µl 1mg/ml  $325.00
Immunohistochemistry analysis of paraffin-embedded human placenta, using GTPase Activating Protein (Phospho-Ser387) Antibody. The picture on the right is blocked with the phospho peptide.
Immunofluorescence analysis of HeLa cells, using GTPase Activating Protein (Phospho-Ser387) Antibody. The picture on the right is blocked with the phospho peptide.

RACGAP1 / MGCRACGAP Antibody LS-C753610
Rabbit Polyclonal (IgG) to Human RACGAP1 / MGCRACGAP
Human
ELISA, IF, IHC, IP, WB
Unconjugated
100µg  $355.00

RACGAP1 / MGCRACGAP Antibody (330-410 aa) LS-C385728
Rabbit Polyclonal (IgG) to Human RACGAP1 / MGCRACGAP
Mouse, Rat, Human, Monkey
ELISA, IF, IHC, WB
Unconjugated
50µl 1mg/ml  $235.00; 100µl 1mg/ml  $265.00; 200µl 1mg/ml  $335.00
Western blot of Rac GAP1 antibody

RACGAP1 / MGCRACGAP Antibody LS-C682136
Rabbit Polyclonal (IgG) to Human RACGAP1 / MGCRACGAP
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50µl  $235.00; 100µl  $285.00
Immunohistochemistry of paraffin-embedded human thymus tissue at dilution 1:100
Immunohistochemistry of paraffin-embedded human testis tissue at dilution 1:100

RACGAP1 / MGCRACGAP Antibody (Leu383) LS-C176541
Rabbit Polyclonal to Human RACGAP1 / MGCRACGAP
Mouse, Rat, Human
IF, IHC, IHC-P, WB
Unconjugated
100µl  $345.00
IHC of MgcRacGAP (L383) pAb in paraffin-embedded human brain tissue.
Western blot of MgcRacGAP (L383) pAb in extracts from COS7 cells.

RACGAP1 / MGCRACGAP Antibody LS-C801668
Rabbit Polyclonal (IgG) to Human RACGAP1 / MGCRACGAP
Mouse, Rat, Human, Monkey
ELISA, IF, WB
Unconjugated
100µl 1mg/ml  $325.00; 200µl 1mg/ml  $375.00
Immunofluorescence Image
Immunofluorescence Image
Showing 1-25 of 67 results

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For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).