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RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. Augments the production of reactive oxygen species (ROS) by NADPH oxidase.
| Gene Name: | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) |
| Family/Subfamily: | Ras GTPase superfamily IPR001806 , not assigned-Ras GTPase superfamily IPR001806 |
| Synonyms: | RAC2, EN-7, Gx, p21-Rac2, Small G protein, HSPC022 |
| Target Sequences: | NM_002872 NP_002863.1 P15153 |
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