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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Rabbit IgG Fab

The fragment antigen-binding (Fab fragment) is a region on an antibody that binds to antigens. It is composed of one constant and one variable domain of each of the heavy and the light chain. These domains shape the paratope — the antigen-binding site — at the amino terminal end of the monomer. The two variable domains bind the epitope on their specific antigens. In an experimental setting, Fc and Fab fragments can be generated in the laboratory. The enzyme papain can be used to cleave an immunoglobulin monomer into two Fab fragments and an Fc fragment. The enzyme pepsin cleaves below hinge region, so a F(ab')2 fragment and a pFc' fragment is formed. Recently another enzyme for generation of F(ab')2 has been commercially available. The enzyme IdeS (Immunoglobulin degrading enzyme from Streptococcus pyogenes, trade name FabRICATOR) cleaves IgG in a sequence specific manner at neutral pH. The F(ab')2 fragment can be split into two Fab' fragments by mild reduction. The variable regions of the heavy and light chains can be fused together to form a single-chain variable fragment (scFv), which is only half the size of the Fab fragment, yet retains the original specificity of the parent immunoglobulin.

Rabbit IgG Fab Target Details

Target Name: Rabbit IgG Fab

Filtered By: None
Target
Rabbit IgG Fab (7)
Reactivity
Rabbit (7)
Application
WB (4)
ELISA (6)
ID (1)
Host
goat (3)
guinea pig (4)
Isotype
IgG (6)
Clonality
polyclonal pc (7)
Format
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
Unconjugated (4)
Publications
No (7)
Showing 1-7 of 7 results

Guinea pig Anti-Rabbit IgG Fab Secondary Antibody LS-C212246
Guinea pig Polyclonal (IgG) to Rabbit IgG Fab
Rabbit
ELISA WB
Unconjugated
500µg  $285.00

Guinea pig Anti-Rabbit IgG Fab Secondary Antibody (HRP) LS-C212248
Guinea pig Polyclonal (IgG) to Rabbit IgG Fab
Rabbit
ELISA WB
HRP Conjugated
500µg  $285.00

Guinea pig Anti-Rabbit IgG Fab Secondary Antibody (Biotin) LS-C212250
Guinea pig Polyclonal (IgG) to Rabbit IgG Fab
Rabbit
ELISA WB
Biotin Conjugated
500µg 0.25mg/ml  $245.00

Guinea pig Anti-Rabbit IgG Fab Secondary Antibody (FITC) LS-C212249
Guinea pig Polyclonal (IgG) to Rabbit IgG Fab
Rabbit
ELISA WB
FITC Conjugated
500µg  $285.00

Goat Anti-Rabbit IgG Fab Secondary Antibody LS-C350872
Goat Polyclonal (IgG) to Rabbit IgG Fab
Rabbit
ELISA
Unconjugated
500µg 0.5mg/ml  $225.00

Goat Anti-Rabbit IgG Fab Secondary Antibody LS-C350900
Goat Polyclonal (IgG) to Rabbit IgG Fab
Rabbit
ELISA
Unconjugated
500µg 0.5mg/ml  $235.00

Goat Anti-Rabbit IgG Fab Secondary Antibody LS-C347353
Goat Polyclonal to Rabbit IgG Fab
Rabbit
ID
Unconjugated
1ml  $305.00
Showing 1-7 of 7 results

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).


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