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RAB8B
RAB8B, member RAS oncogene family
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab may be involved in polarized vesicular trafficking and neurotransmitter release. May participate in cell junction dynamics in Sertoli cells.
| Gene Name: | RAB8B, member RAS oncogene family |
| Family/Subfamily: | Ras GTPase superfamily IPR001806 , not assigned-Ras GTPase superfamily IPR001806 |
| Synonyms: | RAB8B, RAB-8b protein, Ras-related protein Rab-8B |
| Target Sequences: | NM_016530 NP_057614.1 Q92930 |
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