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RAB7B

RAB7B, member RAS oncogene family

Controls vesicular trafficking from endosomes to the trans-Golgi network (TGN). Acts as a negative regulator of TLR9 signaling and can suppress TLR9-triggered TNFA, IL6, and IFNB production in macrophages by promoting TLR9 lysosomal degradation. Also negatively regulates TLR4 signaling in macrophages by promoting lysosomal degradation of TLR4. Promotes megakaryocytic differentiation by increasing NF-kappa-B-dependent IL6 production and subsequently enhancing the association of STAT3 with GATA1. Not involved in the regulation of the EGF- and EGFR degradation pathway.

Gene Name: RAB7B, member RAS oncogene family
Synonyms: RAB7B, RAB7, Ras-related protein Rab-7, Ras-related protein Rab-7b
Target Sequences: Q96AH8 Q96AH8

☰ Filters
Products
Antibodies (19)
Primary (19)
RAB7B (19)
Human (19)
IHC (1)
WB (15)
ELISA (12)
IF (1)
rabbit (18)
mouse (1)
IgG (16)
IgG2a,k (1)
monoclonal mc (1)
polyclonal pc (18)
1C3 (1)
APC Conjugated (2)
Azide-free (1)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (2)
Unconjugated (6)
aa168-197 (7)
aa1-199 (1)
No (19)
Select
RAB7B Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$331
RAB7B Antibody - Immunofluorescence staining of Hela cells diluted at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C.The Secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG (H+L).
Select
RAB7B Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF
Unconjugated
50 µg/$294; 100 µg/$360
Select
RAB7B Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
RAB7B Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
RAB7B Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
RAB7B Antibody - Western blot of RAB7B expression in transfected 293T cell line by RAB7B monoclonal antibody (M02), clone 1C3.
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RAB7B Mouse anti-Human Monoclonal (1C3) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
Select
RAB7B Rabbit anti-Human Polyclonal (aa168-197) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Select
RAB7B Rabbit anti-Human Polyclonal (aa168-197) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
RAB7B Rabbit anti-Human Polyclonal (aa168-197) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
RAB7B Rabbit anti-Human Polyclonal (aa168-197) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
RAB7B Rabbit anti-Human Polyclonal (aa168-197) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
RAB7B Rabbit anti-Human Polyclonal (aa168-197) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
Select
RAB7B Rabbit anti-Human Polyclonal (aa1-199) Antibody
Human
WB
Unconjugated
100 µg/$749
Select
RAB7B Rabbit anti-Human Polyclonal (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$937
Select
RAB7B Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$937
Select
RAB7B Rabbit anti-Human Polyclonal (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$937
Select
RAB7B Rabbit anti-Human Polyclonal (APC) Antibody
Human
WB
APC Conjugated
100 µl/$937
Select
RAB7B Rabbit anti-Human Polyclonal (PE) Antibody
Human
WB
PE Conjugated
100 µl/$937
RAB7B Antibody - RAB7B Antibody western blot of A2058 cell line lysates (35 ug/lane). The RAB7B antibody detected the RAB7B protein (arrow).
Select
RAB7B Rabbit anti-Human Polyclonal (aa168-197) Antibody
Human
WB
Unconjugated
400 µl/$393
Viewing 1-19 of 19 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).