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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
Protein Family And Group
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RAB7A / RAB7

RAB7A, member RAS oncogene family

Key regulator in endo-lysosomal trafficking. Governs early-to-late endosomal maturation, microtubule minus-end as well as plus-end directed endosomal migration and positioning, and endosome-lysosome transport through different protein-protein interaction cascades. Plays a central role, not only in endosomal traffic, but also in many other cellular and physiological events, such as growth-factor-mediated cell signaling, nutrient-transportor mediated nutrient uptake, neurotrophin transport in the axons of neurons and lipid metabolism. Also involved in regulation of some specialized endosomal membrane trafficking, such as maturation of melanosomes, pathogen-induced phagosomes (or vacuoles) and autophagosomes. Plays a role in the maturation and acidification of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. Plays a role in the fusion of phagosomes with lysosomes. Plays important roles in microbial pathogen infection and survival, as well as in participating in the life cycle of viruses. Microbial pathogens possess survival strategies governed by RAB7A, sometimes by employing RAB7A function (e.g. Salmonella) and sometimes by excluding RAB7A function (e.g. Mycobacterium). In concert with RAC1, plays a role in regulating the formation of RBs (ruffled borders) in osteoclasts. Controls the endosomal trafficking and neurite outgrowth signaling of NTRK1/TRKA. Regulates the endocytic trafficking of the EGF-EGFR complex by regulating its lysosomal degradation.

Gene Name: RAB7A, member RAS oncogene family
Synonyms: RAB7A, CMT2B, PRO2706, RAB7, Ras-associated protein RAB7, Ras-related protein Rab-7a, PSN
Target Sequences: NM_004637 AAA86640.1 P51149

Viewing 1-25 of 34 items
RAB7A / RAB7 Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Goat Polyclonal (IgG) to Mouse RAB7A / RAB7
Mouse, Dog, Rat, Human, Monkey
IF, IHC, IHC-P, WB
Unconjugated
100µl   3mg/ml   $425.00
RAB7A / RAB7 Antibody - Anti-RAB7 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Select
Rabbit Polyclonal to Human RAB7A / RAB7
Xenopus, Chicken, Zebrafish, Dog, Rat, Bovine, Human, Monkey
IHC, IHC-P, WB
Unconjugated
50µg   1mg/ml   $425.00
RAB7A / RAB7 Antibody - Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Rabbit Polyclonal (IgG) to Human RAB7A / RAB7
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50µl   $425.00
RAB7A / RAB7 Antibody - Immunohistochemistry of paraffin-embedded human gastric cancer tissue using RAB7A Antibody at dilution of 1:100
Select
Rabbit Polyclonal (IgG) to Human RAB7A / RAB7
Human
ELISA, IF, IHC
Unconjugated
50µg   $285.00; 100µg   2.5mg/ml   $385.00
Select
Rabbit Polyclonal (IgG) to Human RAB7A / RAB7
Human
ELISA, WB
Unconjugated
200µl   $590.00
Select
Rabbit Polyclonal (IgG) to Human RAB7A / RAB7
Human
ELISA, WB
Biotin Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human RAB7A / RAB7
Human
ELISA, WB
FITC Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human RAB7A / RAB7
Human
ELISA, WB
PE Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human RAB7A / RAB7
Human
ELISA, WB
APC Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human RAB7A / RAB7
Human
ELISA, WB
AP Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human RAB7A / RAB7
Human
ELISA, WB
HRP Conjugated, Azide-free
200µl   $740.00
RAB7A / RAB7 Antibody - Detection of RAB7 in NIH/3T3 cell lysates.
Select
Rabbit Polyclonal to Human RAB7A / RAB7
Mouse, Dog, Sheep, Bovine, Rat, Human
WB
Unconjugated
100µl   $335.00
Select
Rabbit Monoclonal (IgG) to Human RAB7A / RAB7
Mouse, Rat, Human
WB
Unconjugated
50µl   $265.00; 100µl   $345.00; 200µl   $445.00
RAB7A / RAB7 Antibody - ICC/IF analysis of RAB7A in HeLa cells. The cell was stained with RAB7A antibody (1:100). The secondary antibody (green) was used Alexa Fluor 488. DAPI was stained the cell nucleus (blue).
Select
Mouse Monoclonal [clone AT10E4] (IgG2a,k) to Human RAB7A / RAB7
Human
ELISA, Flo, ICC, WB
Unconjugated
50µl   1mg/ml   $275.00; 100µl   1mg/ml   $345.00
RAB7A / RAB7 Antibody - Formalin-fixed and paraffin-embedded human skeletal muscle reacted with RAB7 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Select
Rabbit Polyclonal to Human RAB7A / RAB7
Human
Flo, IHC, IHC-P, WB
Unconjugated
400µl   $325.00
RAB7A / RAB7 Antibody
Select
Rabbit Polyclonal (IgG) to Human RAB7A / RAB7
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100µl   1mg/ml   $325.00; 200µl   1mg/ml   $375.00
RAB7A / RAB7 Antibody - Immunochemical staining of human RAB7A in human kidney with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.
Select
Rabbit Polyclonal (IgG) to Human RAB7A / RAB7
Human
ICC, IF, IHC-P
Unconjugated
50µl   $235.00; 100µl   $275.00; 200µl   $305.00
RAB7A / RAB7 Antibody - Anti-RAB7A rabbit polyclonal antibody at 1:500 dilution. Lane A: A431 Whole Cell Lysate. Lysates/proteins at 30 ug per lane. Secondary: Goat Anti-Rabbit IgG H&L (Dylight 800) at 1/10000 dilution. Developed using the Odyssey technique. Performed under reducing conditions. Predicted band size: 23 kDa. Observed band size: 23 kDa.
Select
Rabbit Polyclonal (IgG) to Human RAB7A / RAB7
Human
ICC, IF, WB
Unconjugated, Preservative Free
50µl   $235.00; 100µl   $275.00; 200µl   $305.00
Select
Rabbit Polyclonal to Rat RAB7A / RAB7
Rat
ELISA, IHC, IHC-P, IP, WB
Unconjugated
50µl   $235.00; 100µl   $275.00; 200µl   $305.00
Select
Rabbit Polyclonal (IgG) to Human RAB7A / RAB7
Human
ELISA, IHC, WB
Unconjugated
100µg   $335.00
RAB7A / RAB7 Antibody
Select
Rabbit Polyclonal (IgG) to Human RAB7A / RAB7
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100µl   1mg/ml   $325.00; 200µl   1mg/ml   $375.00
RAB7A / RAB7 Antibody - IHC of Rab7 pAb in paraffin-embedded human breast carcinoma tissue.
Select
Rabbit Polyclonal to Human RAB7A / RAB7
Human
IHC, IHC-P, WB
Unconjugated
100µl   $345.00
Select
Mouse Monoclonal [clone PAT10E4AT] (IgG2a,k) to Human RAB7A / RAB7
Human
ELISA, WB
Unconjugated
5µg   $195.00; 20µg   $255.00; 100µg   $475.00
RAB7A / RAB7 Antibody - Western blot of RAB7A pAb in extracts from K562 cells.
Select
Rabbit Polyclonal to Human RAB7A / RAB7
Mouse, Rat, Human
IHC, WB
Unconjugated
100µl   $385.00
Select
Rabbit Polyclonal to Human RAB7A / RAB7
Mouse, Rat, Human
ELISA, WB
Unconjugated
100µg   $315.00

Viewing 1-25 of 34 items


If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).