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RAB6A / RAB6

RAB6A, member RAS oncogene family

RAB6A / RAB6 is a member of the RAB family, which belongs to the small GTPase superfamily. GTPases of the RAB family bind to various effectors to regulate the targeting and fusion of transport carriers to acceptor compartments. This protein is located at the Golgi apparatus, which regulates trafficking in both a retrograde (from early endosomes and Golgi to the endoplasmic reticulum) and an anterograde (from the Golgi to the plasma membrane) directions. Myosin II is an effector of this protein in these processes. This protein is also involved in assembly of human cytomegalovirus (HCMV) by interacting with the cellular protein Bicaudal D1, which interacts with the HCMV virion tegument protein, pp150. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

Gene Name: RAB6A, member RAS oncogene family
Family/Subfamily: Ras GTPase superfamily IPR001806 , RAS oncogene
Synonyms: RAB6A, Rab GTPase, Rab-6, RAB6, Ras-related protein rab-6, RAB6A', Ras-related protein Rab-6A
Target Sequences: NM_002869 NP_002860.2 P20340

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Proteins (10)
Over-Expression Lysate (4)
Recombinant (6)
RAB6A / RAB6 (10)
No (10)
GST (1)
GST, N-terminus (1)
His (1)
His-SUMO (1)
Myc-DDK (Flag) (6)
Human (8)
293T Cells (2)
E. coli (2)
HEK 293 Cells (4)
Wheat Germ Extract (2)
Purified (2)
RAB6A / RAB6 Protein - Purified recombinant protein RAB6A was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
23.4 kDa
20 µg/$1,107
RAB6A / RAB6 Protein - Purified recombinant protein RAB6A was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
23.4 kDa
20 µg/$1,107
RAB6A / RAB6 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
RAB6A / RAB6 Protein
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E. coli
His-SUMO
39.4 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
RAB6A / RAB6 Protein - 12.5% SDS-PAGE of human RAB6A stained with Coomassie Blue
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Wheat Germ Extract
GST
48.51 kDa
10 µg/$479; 25 µg/$670
RAB6A / RAB6 Protein
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E. coli
His
50 µg/$361; 250 µg/$739; 10 µg/$261
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293T Cells
Myc-DDK (Flag)
23.4 kDa
20 µg/$150
RAB6A / RAB6 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
23.4 kDa
20 µg/$150
RAB6A / RAB6 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
23.4 kDa
100 µg/$494
RAB6A / RAB6 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
23.4 kDa
100 µg/$494
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).