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RAB35

RAB35, member RAS oncogene family

The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab is involved in the process of endocytosis and is an essential rate-limiting regulator of the fast recycling pathway back to the plasma membrane. During cytokinesis, required for the postfurrowing terminal steps, namely for intercellular bridge stability and abscission, possibly by controlling phosphatidylinositol 4,5-bis phosphate (PIP2) and SEPT2 localization at the intercellular bridge. May indirectly regulate neurite outgrowth.

Gene Name: RAB35, member RAS oncogene family
Family/Subfamily: Ras GTPase superfamily IPR001806 , RAS oncogene
Synonyms: RAB35, GTP-binding protein RAY, H-ray, RAB1C, Ras-related protein Rab-35, Ras-related protein Rab-1C, RAY
Target Sequences: NM_006861 NP_006852.1 Q15286

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Proteins (7)
Over-Expression Lysate (4)
Recombinant (3)
RAB35 (7)
No (7)
GST (1)
His (1)
Myc-DDK (Flag) (5)
Human (5)
293T Cells (2)
E. coli (1)
HEK 293 Cells (3)
Wheat Germ Extract (1)
Purified (2)
RAB35 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
17.5 kDa
100 µg/$494
RAB35 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
22.8 kDa
100 µg/$494
RAB35 Protein - 12.5% SDS-PAGE of human RAB35 stained with Coomassie Blue
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Wheat Germ Extract
GST
47.85 kDa
10 µg/$479; 25 µg/$670
RAB35 Protein - Purified recombinant protein RAB35 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
22.8 kDa
20 µg/$1,107
RAB35 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
17.5 kDa
20 µg/$150
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293T Cells
Myc-DDK (Flag)
22.8 kDa
20 µg/$150
RAB35 Protein
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E. coli
His
50 µg/$411; 250 µg/$985; 10 µg/$276
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).