RAB11B

RAB11B, member RAS oncogene family

The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab plays a role in endocytic recycling, regulating apical recycling of several transmembrane proteins including cystic fibrosis transmembrane conductance regulator/CFTR, epithelial sodium channel/ENaC, potassium voltage-gated channel, and voltage-dependent L-type calcium channel. May also regulate constitutive and regulated secretion, like insulin granule exocytosis. Required for melanosome transport and release from melanocytes. Also regulates V-ATPase intracellular transport in response to extracellular acidosis.

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Products

Proteins (6)

Type

Over-Expression Lysate (2)

Recombinant (4)

Target

RAB11B (6)

Publications

No (6)

Tag

GST (1)

GST, N-terminus (1)

His (1)

Myc-DDK (Flag) (3)

Species

Human (5)

Source

293T Cells (1)

HEK 293 Cells (2)

Human Cells (1)

Wheat Germ Extract (2)

Purification

Purified (1)

Low Endotoxin Level

Low endotoxin level (1)

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Human RAB11B Protein (Recombinant His) (Gly2-Cys215) - LS-G97813

Source:

Human Cells

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

26.3 kDa

Price:

100 µg/$843

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RAB11B Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G116803

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

24.3 kDa

Price:

100 µg/$494

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Human RAB11B Protein (Recombinant GST) (Full Length) - LS-G31540

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

50.9 kDa

Price:

10 µg/$479; 25 µg/$670

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Human RAB11B Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66817

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

24.3 kDa

Price:

20 µg/$1,107

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Human RAB11B Protein (Recombinant GST, N-terminus) (aa1-110) - LS-G61040

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human RAB11B Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78544

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

24.3 kDa

Price:

20 µg/$150

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