R1 / RRM1

ribonucleotide reductase M1

R1 / RRM1 is one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region.

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Products

Proteins (8)

Type

Over-Expression Lysate (2)

Recombinant (6)

Target

R1 / RRM1 (8)

Publications

No (8)

Tag

GST, N-terminus (2)

His (1)

His-S (1)

His-SUMO (1)

Myc-DDK (Flag) (3)

Species

Human (7)

Source

293T Cells (1)

E. coli (2)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Yeast (1)

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Human R1 / RRM1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66888

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

89.9 kDa

Price:

20 µg/$1,107

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Human R1 / RRM1 Protein (Recombinant His) (Full Length) - LS-G23112

Source:

Yeast

Tag:

His

Molecular Weight:

92.07 kD

Price:

1 mg/$1,607; 100 µg/$469; 20 µg/$349

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Human R1 / RRM1 Protein (Recombinant His-SUMO) (Full Length) - LS-G21145

Source:

E. coli

Tag:

His-SUMO

Molecular Weight:

106.01 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human R1 / RRM1 Protein (Recombinant GST, N-terminus) (aa644-753) - LS-G60004

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human R1 / RRM1 Protein (Recombinant GST, N-terminus) (aa593-792) - LS-G60005

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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R1 / RRM1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G120880

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

89.9 kDa

Price:

100 µg/$494

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Human R1 / RRM1 Protein (Recombinant His-S) (aa1-213) - LS-G25669

Source:

E. coli

Tag:

His-S

Molecular Weight:

28 kDa

Price:

10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119

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Human R1 / RRM1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78659

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

89.9 kDa

Price:

20 µg/$150

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