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PXN / Paxillin

paxillin

PXN / Paxillin is a cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. These isoforms exhibit different expression pattern, and have different biochemical, as well as physiological properties (PMID:9054445).

Gene Name: paxillin
Synonyms: PXN, Paxillin
Target Sequences: NM_002859 NP_002850.2 P49023

Publications (3)

1
RhoC GTPase is required for PC-3 prostate cancer cell invasion but not motility. Yao H, Dashner EJ, van Golen CM, van Golen KL. Oncogene. 2006 25:2285-96. [PubMed:16314838]
2
GIT1 utilizes a focal adhesion targeting-homology domain to bind paxillin. Schmalzigaug R, Garron ML, Roseman JT, Xing Y, Davidson CE, Arold ST, Premont RT. Cellular signalling. 2007 19:1733-44. (ICC, IP) [PubMed:17467235] [PMC:PMC2025689]
3
Podosomes are present in a postsynaptic apparatus and participate in its maturation. Proszynski TJ, Gingras J, Valdez G, Krzewski K, Sanes JR. Proceedings of the National Academy of Sciences of the United States of America. 2009 106:18373-8. [PubMed:19822767] [PMC:PMC2775295]

☰ Filters
Products
Proteins (17)
Over-Expression Cell Culture Supernatant (1)
Over-Expression Lysate (7)
Recombinant (9)
PXN / Paxillin (17)
No (17)
6His, N-terminus (3)
GST (3)
His, N-Terminal (1)
His-T7 (3)
Myc-DDK (Flag) (7)
Human (12)
Mouse (1)
Rat (1)
293T Cells (3)
E. coli (5)
HEK 293 Cells (6)
Wheat Germ Extract (3)
Purified (3)
PXN / Paxillin Protein
Select
E. coli
6His, N-terminus
63 kDa
10 µg/$265; 50 µg/$315; 100 µg/$365; 250 µg/$518
PXN / Paxillin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
64.3 kDa
100 µg/$494
PXN / Paxillin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
46.4 kDa
100 µg/$494
PXN / Paxillin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
60.8 kDa
20 µg/$215
PXN / Paxillin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
64.3 kDa
20 µg/$150
PXN / Paxillin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
46.4 kDa
20 µg/$150
PXN / Paxillin Protein
Select
E. coli
His, N-Terminal
46.4 kDa
50 µg/$419
Select
Wheat Germ Extract
GST
28.16 kDa
10 µg/$479; 25 µg/$670
Select
Wheat Germ Extract
GST
54.1 kDa
10 µg/$479; 25 µg/$670
Select
Wheat Germ Extract
GST
28.6 kDa
10 µg/$479; 25 µg/$670
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HEK 293 Cells
6His, N-terminus
63 kDa
100 µg/$298
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HEK 293 Cells
6His, N-terminus
63 kDa
200 µl/$283
PXN / Paxillin Protein - Purified recombinant protein PXN was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
60.8 kDa
20 µg/$1,107
PXN / Paxillin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
60.8 kDa
100 µg/$710
PXN / Paxillin Protein - Recombinant Paxillin By SDS-PAGE
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E. coli
His-T7
31.2 kDa
10 µg/$286; 50 µg/$472; 100 µg/$752; 200 µg/$942; 1 mg/$2,069; 500 µg/$1,600; 5 mg/$3,291; 2 mg/$2,257
PXN / Paxillin Protein - Recombinant Paxillin By SDS-PAGE
Select
E. coli
His-T7
32.1 kDa
10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148
PXN / Paxillin Protein - Recombinant Paxillin By SDS-PAGE
Select
E. coli
His-T7
30.2 kDa
10 µg/$284; 50 µg/$460; 100 µg/$735; 200 µg/$917; 1 mg/$2,037; 500 µg/$1,571; 5 mg/$3,207; 2 mg/$2,225
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).