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Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
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Unfortunately, the antibody (ID:155954) is no longer available.
Below is a list of antibodies to the same protein target. You may also try your search again using the search box at the top of the page.
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PVRL4 / Nectin 4
poliovirus receptor-related 4
PVRL4 / Nectin 4 is a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.
Adherens junction protein nectin-4 is the epithelial receptor for measles virus. Mhlebach MD, Mateo M, Sinn PL, Prfer S, Uhlig KM, Leonard VH, Navaratnarajah CK, Frenzke M, Wong XX, Sawatsky B, Ramachandran S, McCray PB, Cichutek K, von Messling V, Lopez M, Cattaneo R. Nature. 2011 480:530-3. (Flo; Human)[Full Text Article]
Related Antibodies: LS-C37483.