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PVRL3 / Nectin-3

poliovirus receptor-related 3

Plays a role in cell-cell adhesion through heterophilic trans-interactions with nectin-like proteins or nectins, such as trans-interaction with PVRL2/nectin-2 at Sertoli-spermatid junctions. Trans-interaction with PVR induces activation of CDC42 and RAC small G proteins through common signaling molecules such as SRC and RAP1. Also involved in the formation of cell-cell junctions, including adherens junctions and synapses. Induces endocytosis-mediated down-regulation of PVR from the cell surface, resulting in reduction of cell movement and proliferation. Plays a role in the morphology of the ciliary body.

Gene Name: poliovirus receptor-related 3
Synonyms: PVRL3, CDW113, DKFZP566B0846, Nectin 3, PPR3, Poliovirus receptor-related 3, CD113, CD113 antigen, NECTIN-3, PVRR3
Target Sequences: NM_015480 NP_056295.1 Q9NQS3

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ELISA Kits (4)
Custom (3)
Sandwich (1)
PVRL3 / Nectin-3 (4)
Human (3)
Mouse (1)
96-Well Microplate (1)
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No (4)
Cell Culture Supernatants (1)
EDTA Plasma (1)
Heparin Plasma (1)
Serum (1)
PVRL3 / Nectin-3 ELISA Kit
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Custom
96-Well Microplate
Human
Colorimetric - 450nm (TMB)
1 Plate/$923
PVRL3 / Nectin-3 ELISA Kit
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Custom
96-Well Strip Plate
Human
1 Plate/$783
PVRL3 / Nectin-3 ELISA Kit
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Sandwich
Human
125 - 8000 pg/ml
Cell Culture Supernatants, EDTA Plasma, Heparin Plasma, Serum
1 Plate/$1,150
PVRL3 / Nectin-3 ELISA Kit
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Custom
96-Well Strip Plate
Mouse
1 Plate/$783
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).