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PVRL2 / CD112

poliovirus receptor-related 2 (herpesvirus entry mediator B)

PVRL2 / CD112 is a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Gene Name: poliovirus receptor-related 2 (herpesvirus entry mediator B)
Synonyms: PVRL2, HVEB, Herpesvirus entry protein B, Poliovirus receptor-like 2, Nectin-2, PRR2, PVRR2, CD112, CD112 antigen, Herpes virus entry mediator B, Herpesvirus entry mediator B, NECTIN2
Target Sequences: NM_002856 NP_002847.1 Q92692

☰ Filters
Products
Proteins (18)
Over-Expression Lysate (3)
Recombinant (15)
PVRL2 / CD112 (18)
No (18)
6His, C-terminus (5)
6His, N-terminus (1)
AVI-6His, C-terminus (1)
GST (1)
His (2)
His-T7 (2)
Mouse IgG2a Fc, C-terminus (1)
Myc-DDK (Flag) (4)
Human (12)
Mouse (4)
Rat (1)
293T Cells (2)
E. coli (3)
HEK 293 Cells (2)
Human (2)
Human Cells (5)
Mammalian Cells (3)
Wheat Germ Extract (1)
Purified (4)
Low endotoxin level (10)
Biologically active (2)
PVRL2 / CD112 Protein - Recombinant Human PVRL2/Nectin-2/CD112 (C-6His-Avi) Biotinylated
Select
Human
AVI-6His, C-terminus
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
38.4 kDa
20 µg/$416; 100 µg/$910
PVRL2 / CD112 Protein - Recombinant Human PVRL2/Nectin-2/CD112 (C-mIgG2a Fc)
Select
Human
Mouse IgG2a Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
62.6 kDa
10 µg/$273; 50 µg/$398
PVRL2 / CD112 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
51.4 kDa
100 µg/$494
PVRL2 / CD112 Protein - 12.5% SDS-PAGE of human PVRL2 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
78.43 kDa
10 µg/$479; 25 µg/$670
PVRL2 / CD112 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
E. coli
6His, N-terminus
1 mg/$1,355; 100 µg/$420; 20 µg/$323
Select
Human Cells
None
Less than 1.0 EU/µg protein (determined by LAL method).
36.2 kDa
100 µg/$721
PVRL2 / CD112 Protein - Purified recombinant protein NECTIN2 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
54.4 kDa
20 µg/$1,107
Select
293T Cells
Myc-DDK (Flag)
51.4 kDa
20 µg/$150
PVRL2 / CD112 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
51.4 kDa
20 µg/$150
Select
Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
36 kDa
100 µg/$721
Select
Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
36 kDa
100 µg/$721
Select
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
35.6kD
10 µg/$248; 50 µg/$321; 500 µg/$869; 1 mg/$1,203
PVRL2 / CD112 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
Mammalian Cells
6His, C-terminus
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
36.58 kDa
50 µg/$424; 10 µg/$288; 1 mg/$2,837; 500 µg/$1,987
Select
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
36.58kD
10 µg/$269; 50 µg/$372; 500 µg/$1,585; 1 mg/$2,157
Select
Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
36.6 kDa
10 µg/$269; 50 µg/$368
Select
Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
35.6 kDa
10 µg/$248; 50 µg/$317
PVRL2 / CD112 Protein - Recombinant Poliovirus Receptor Related Protein 2 By SDS-PAGE
Select
E. coli
His-T7
26.8 kDa
10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176
PVRL2 / CD112 Protein - Recombinant Poliovirus Receptor Related Protein 2 By SDS-PAGE
Select
E. coli
His-T7
33.8 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
Viewing 1-18 of 18 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).