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PUM1

pumilio RNA-binding family member 1

PUM1 is a member of the PUF family, evolutionarily conserved RNA-binding proteins related to the Pumilio proteins of Drosophila and the fem-3 mRNA binding factor proteins of C. elegans. The encoded protein contains a sequence-specific RNA binding domain comprised of eight repeats and N- and C-terminal flanking regions, and serves as a translational regulator of specific mRNAs by binding to their 3' untranslated regions. The evolutionarily conserved function of the encoded protein in invertebrates and lower vertebrates suggests that the human protein may be involved in translational regulation of embryogenesis, and cell development and differentiation. Alternatively spliced transcript variants encoding different isoforms have been described.

Gene Name: pumilio RNA-binding family member 1
Synonyms: PUM1, KIAA0099, PUML1, Pumilio homolog 1, Pumilio homolog 1 (Drosophila), HSPUM, PUMH, PUMH1, Pumilio (Drosophila) homolog 1, Pumilio-1
Target Sequences: NM_014676 NP_055491.1 Q14671

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Proteins (3)
Over-Expression Lysate (2)
Recombinant (1)
PUM1 (3)
No (3)
Myc-DDK (Flag) (3)
Human (2)
293T Cells (1)
HEK 293 Cells (2)
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293T Cells
Myc-DDK (Flag)
126.3 kDa
20 µg/$150
PUM1 Protein - Purified recombinant protein PUM1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
126.3 kDa
20 µg/$1,107
PUM1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
126.3 kDa
100 µg/$494
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).