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PTRF / CAVIN

polymerase I and transcript release factor

PTRF / CAVIN is a protein that enables the dissociation of paused ternary polymerase I transcription complexes from the 3' end of pre-rRNA transcripts. This protein regulates rRNA transcription by promoting the dissociation of transcription complexes and the reinitiation of polymerase I on nascent rRNA transcripts. This protein also localizes to caveolae at the plasma membrane and is thought to play a critical role in the formation of caveolae and the stabilization of caveolins. This protein translocates from caveolae to the cytoplasm after insulin stimulation. Caveolae contain truncated forms of this protein and may be the site of phosphorylation-dependent proteolysis. This protein is also thought to modify lipid metabolism and insulin-regulated gene expression. Mutations in this gene result in a disorder characterized by generalized lipodystrophy and muscular dystrophy.

Gene Name: polymerase I and transcript release factor
Synonyms: PTRF, Cavin-1, CAVIN1, CAVIN, CGL4, FKSG13, TTF-I interacting peptide 12
Target Sequences: AF000421 AAC63404.1 Q6NZI2

☰ Filters
Antibodies (20)
Proteins (5)
ELISA Kits (4)
Over-Expression Lysate (2)
Primary (20)
Recombinant (3)
Sandwich (4)
PTRF / CAVIN (29)
Human (22)
Mouse (12)
Rat (7)
Bovine (3)
Chimpanzee (3)
Gibbon (3)
Horse (3)
Monkey (3)
Pig (3)
Rabbit (3)
IHC (9)
IHC-P (7)
WB (18)
ELISA (5)
IF (4)
IP (4)
Peptide-ELISA (1)
rabbit (19)
mouse (1)
Product Group
IHCPlus (3)
IgG (11)
IgG2b,k (1)
monoclonal mc (1)
polyclonal pc (19)
1F7 (1)
96-Well Strip Plate (4)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
Unconjugated (14)
aa177-226 (4)
aa214-263 (4)
C-Terminus (1)
aa1-30 (1)
aa125-175 (1)
aa150-200 (1)
aa238-288 (1)
aa363-390 (1)
No (29)
Plasma (4)
Serum (4)
Tissue Homogenates (1)
GST (1)
GST, N-terminus (1)
Myc-DDK (Flag) (3)
Human (4)
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (1)
PTRF / CAVIN Antibody - Immunoperoxidase of monoclonal antibody to PTRF on formalin-fixed paraffin-embedded human pancreas. [antibody concentration 3 ug/ml]
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PTRF / CAVIN Mouse anti-Human Monoclonal (1F7) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
100 µg/$423
PTRF / CAVIN Antibody - Anti-PTRF antibody IHC of mouse vessel and adipocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PTRF / CAVIN Rabbit anti-Mouse Polyclonal (aa177-226) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$460
PTRF / CAVIN Antibody - Anti-PTRF antibody IHC of mouse vessel and adipocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PTRF / CAVIN Rabbit anti-Mouse Polyclonal (aa177-226) (HRP) Antibody
Rabbit, Mouse, Bovine, Pig, Human
IHC, IHC-P, WB
HRP Conjugated
100 µl/$442
PTRF / CAVIN Antibody - Anti-PTRF antibody IHC of mouse vessel and adipocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PTRF / CAVIN Rabbit anti-Mouse Polyclonal (aa177-226) (Biotin) Antibody
Rabbit, Mouse, Bovine, Pig, Human
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$442
PTRF / CAVIN Antibody - Anti-PTRF antibody IHC of mouse vessel and adipocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
PTRF / CAVIN Rabbit anti-Mouse Polyclonal (aa177-226) (FITC) Antibody
Rabbit, Mouse, Bovine, Pig, Human
IHC, IHC-P, WB
FITC Conjugated
100 µl/$442
PTRF / CAVIN Antibody - Anti-PTRF antibody IHC of human breast, adipocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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PTRF / CAVIN Rabbit anti-Human Polyclonal (aa1-30) Antibody
Human
IHC, IHC-P, WB
Unconjugated
200 µl/$460
PTRF / CAVIN Antibody - Anti-PTRF / CAVIN antibody IHC staining of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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PTRF / CAVIN Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
0.05 mg/$460
PTRF / CAVIN Antibody - PTRF / CAVIN antibody Western Blot of MCF7. Antibody dilution: 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PTRF / CAVIN Rabbit anti-Human Polyclonal (aa214-263) Antibody
Human
WB
Unconjugated
100 µl/$424
PTRF / CAVIN Antibody - PTRF / CAVIN antibody Western Blot of MCF7. Antibody dilution: 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PTRF / CAVIN Rabbit anti-Human Polyclonal (aa214-263) (HRP) Antibody
Mouse, Rat, Horse, Gibbon, Chimpanzee, Human, Monkey
WB
HRP Conjugated
100 µl/$469
PTRF / CAVIN Antibody - PTRF / CAVIN antibody Western Blot of MCF7. Antibody dilution: 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PTRF / CAVIN Rabbit anti-Human Polyclonal (aa214-263) (Biotin) Antibody
Mouse, Rat, Horse, Gibbon, Chimpanzee, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
PTRF / CAVIN Antibody - PTRF / CAVIN antibody Western Blot of MCF7. Antibody dilution: 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PTRF / CAVIN Rabbit anti-Human Polyclonal (aa214-263) (FITC) Antibody
Mouse, Rat, Horse, Gibbon, Chimpanzee, Human, Monkey
WB
FITC Conjugated
100 µl/$469
Select
PTRF / CAVIN Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$547
Select
PTRF / CAVIN Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IP, WB
Unconjugated
100 µg/$331
PTRF / CAVIN Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
43.3 kDa
20 µg/$150
PTRF / CAVIN Antibody - Western blot analysis of PTRF using K562 whole cells lysates
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PTRF / CAVIN Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
PTRF / CAVIN Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
Select
PTRF / CAVIN Rabbit anti-Human Polyclonal (aa238-288) Antibody
Mouse, Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
Select
PTRF / CAVIN Rabbit anti-Human Polyclonal (aa125-175) Antibody
Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
Select
PTRF / CAVIN Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µl/$386
PTRF / CAVIN Antibody - Western blot of anti-PTRF Antibody antibody in A375 cell line lysates (35 ug/lane). PTRF(arrow) was detected using the purified antibody.
Select
PTRF / CAVIN Rabbit anti-Human Polyclonal (aa363-390) Antibody
Human
WB
Unconjugated
400 µl/$393
Select
PTRF / CAVIN Rabbit anti-Human Polyclonal (aa150-200) Antibody
Human
IP
Unconjugated
10 µg/$295; 100 µl/$514
PTRF / CAVIN ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
PTRF / CAVIN ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
Select
HEK 293 Cells
Myc-DDK (Flag)
43.3 kDa
20 µg/$1,107
PTRF / CAVIN ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
Viewing 1-25 of 29 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).