PTPRS

protein tyrosine phosphatase, receptor type, S

PTP sigma, n R2B/LAR receptor protein tyrosine phosphatase, is composed of immunoglobulin and fibronectin type-III repeats, a single transmembrane domain and two intracellular catalytic phosphatase domains. PTP sigma has been shown to affect neuronal development and differentiation, proliferation and/or adhesiveness of various cell types in the developing hypothalamo-pituitary axis, development of lung epithelium, and differentiation and development of the neuroendocrine system. Mice lacking PTP sigma exhibit increased neuronatal fatality, stunted growth, developmental delays and severe neurological defects including spastic movements, tremor, ataxic gait, abnormal limb flexion and defective proprioception. Increased expression of PTP sigma may be of pathogenetic significance for the defective insulin secretion in GK rat islets. Two alternatively spliced protein isoforms of PTP sigma have been documented in humans, and the shorter isoform (1502aa) has been shown to expressed strongly in the brain.

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Proteins (12)

Type

Over-Expression Lysate (6)

Recombinant (6)

Target

PTPRS (12)

Publications

No (12)

Tag

GST (1)

His-T7 (2)

Myc-DDK (Flag) (9)

Species

Human (8)

Mouse (1)

Source

293T Cells (3)

E. coli (2)

HEK 293 Cells (6)

Wheat Germ Extract (1)

Purification

Purified (1)

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PTPRS Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G107489

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

165.6 kDa

Price:

100 µg/$494

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PTPRS Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G107587

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

166.1 kDa

Price:

100 µg/$710

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Human PTPRS Protein (Recombinant GST) (Full Length) - LS-G30047

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

36.52 kDa

Price:

10 µg/$479; 25 µg/$670

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Human PTPRS Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G68075

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

209.7 kDa

Price:

20 µg/$1,107

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Human PTPRS Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G68076

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

165.6 kDa

Price:

20 µg/$1,107

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Human PTPRS Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G68077

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

166.1 kDa

Price:

20 µg/$1,107

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Human PTPRS Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G81384

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

165.6 kDa

Price:

20 µg/$150

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Human PTPRS Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G81387

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

166.1 kDa

Price:

20 µg/$215

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Human PTPRS Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G81386

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

209.7 kDa

Price:

20 µg/$215

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PTPRS Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G102216

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

209.7 kDa

Price:

100 µg/$710

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Human PTPRS Protein (Recombinant His-T7) (aa77-361) - LS-G13605

Source:

E. coli

Tag:

His-T7

Molecular Weight:

34.8 kDa

Price:

50 µg/$432; 10 µg/$279; 200 µg/$862; 100 µg/$690; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148

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Mouse PTPRS Protein (Recombinant His-T7) (aa889-1102) - LS-G13609

Source:

E. coli

Tag:

His-T7

Molecular Weight:

28.7 kDa

Price:

10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176

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