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PTPRR

protein tyrosine phosphatase, receptor type, R

PTPRR is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. Silencing of this gene has been associated with colorectal cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares a symbol (PTPRQ) with another gene, protein tyrosine phosphatase, receptor type, Q (GeneID 374462), which is also located on chromosome 12.

Gene Name: protein tyrosine phosphatase, receptor type, R
Family/Subfamily: Protein Phosphatase , R7 receptor
Synonyms: PTPRR, Ch-1 PTPase, Ch-1PTPase, EC-PTP, ECPTP, PTP-SL, NC-PTPCOM1, PC12-PTP1, PCPTP1, R-PTP-R
Target Sequences: NM_002849 NP_002840.2 Q15256

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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).