PTPRQ

protein tyrosine phosphatase, receptor type, Q

Phosphatidylinositol phosphatase required for auditory function. May act by regulating the level of phosphatidylinositol 4,5-bisphosphate (PIP2) level in the basal region of hair bundles. Can dephosphorylate a broad range of phosphatidylinositol phosphates, including phosphatidylinositol 3,4,5-trisphosphate and most phosphatidylinositol monophosphates and diphosphates. Phosphate can be hydrolyzed from the D3 and D5 positions in the inositol ring. Has low tyrosine-protein phosphatase activity; however, the relevance of such activity in vivo is unclear. Plays an important role in adipogenesis of mesenchymal stem cells (MSCs). Regulates the phosphorylation state of AKT1 by suppressing the phosphatidylinositol 3,4,5-trisphosphate (PIP3) level in MSCs and preadipocyte cells.

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Proteins (1)

Type

Recombinant (1)

Target

PTPRQ (1)

Publications

No (1)

Tag

His, N-Terminal (1)

Species

Human (1)

Source

E. coli (1)

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Human PTPRQ Protein (Recombinant His, N-Terminal) (aa36-294) - LS-G25331

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

32.0 kDa

Price:

10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119

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