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Unfortunately, the antibody (ID:10888) is no longer available.

Below is a list of antibodies to the same protein target. You may also try your search again using the search box at the top of the page. Please contact us if you have any questions.



PTPN6 / SHP1

protein tyrosine phosphatase, non-receptor type 6

PTPN6 / SHP1 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. N-terminal part of this PTP contains two tandem Src homolog (SH2) domains, which act as protein phospho-tyrosine binding domains, and mediate the interaction of this PTP with its substrates. This PTP is expressed primarily in hematopoietic cells, and functions as an important regulator of multiple signaling pathways in hematopoietic cells. This PTP has been shown to interact with, and dephosphorylate a wide spectrum of phospho-proteins involved in hematopoietic cell signaling. Multiple alternatively spliced variants of this gene, which encode distinct isoforms, have been reported.

Gene Name: protein tyrosine phosphatase, non-receptor type 6
Family/Subfamily: Protein Phosphatase , NT2
Synonyms: PTPN6, HCP, HPTP1C, Hematopoietic cell phosphatase, PTP-1C, SH-PTP1, SHP-1L, SHP-1, Shptp1, HCPH, PTP1C, SHP1
Target Sequences: NM_002831 NP_002822.2 P29350

Publications (1)

1
Carcinoembryonic antigen-related cell adhesion molecule 1 inhibits proximal TCR signaling by targeting ZAP-70. Chen Z, Chen L, Qiao SW, Nagaishi T, Blumberg RS. Journal of immunology (Baltimore, Md. : 1950). 2008 180:6085-93. (IP) [PubMed:18424730]

Filtered By: None
Target
ptpn6-shp1 (48)
Reactivity
Human (47)
Mouse (19)
Rat (15)
Bovine (1)
Chicken (1)
Chimpanzee (3)
Dog (1)
Gibbon (3)
Hamster (1)
Horse (1)
Monkey (6)
Pig (1)
Rabbit (1)
Application
IHC (13)
IHC-P (10)
WB (44)
Flo (1)
ELISA (26)
ICC (8)
IF (7)
IP (2)
Host
rabbit (34)
mouse (12)
goat (2)
Isotype
IgG (20)
IgG1,k (5)
IgG2a,k (1)
IgG2b (1)
IgG2b,k (2)
Clonality
monoclonal mc (13)
polyclonal pc (35)
Clone
14D5 (1)
1SH01 (2)
Format
Azide-free (1)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (2)
Unconjugated (40)
Epitope
pTyr536 (6)
aa245-294 (4)
aa244-515 (3)
pTyr564 (3)
C-Terminus (2)
Lys530 (1)
aa480-560 (1)
aa500-580 (1)
aa502-551 (1)
aa530-579 (1)
aa553-564 (1)
aa570-582 (1)
Publications
No (48)
Showing 1-25 out of 48 results
Anti-PTPN6 / SHP1 Antibody (clone 14D5) IHC-plus™ LS-B6262

Mouse Monoclonal [clone 14D5] (IgG1,k) to Human PTPN6 / SHP1
Human
ELISA IHC-P WB
Unconjugated
Anti-PTPN6 / SHP1 Antibody IHC-plus™ LS-B6263

Mouse Monoclonal (IgG1,k) to Human PTPN6 / SHP1
Human
ELISA IHC-P WB
Unconjugated
Anti-PTPN6 / SHP1 Antibody IHC-plus™ LS-B14929

Rabbit Polyclonal (IgG) to Human PTPN6 / SHP1
Human
ELISA IF IHC-P WB
Unconjugated
Anti-PTPN6 / SHP1 Antibody (HRP) LS-C318343

Rabbit Polyclonal (IgG) to Human PTPN6 / SHP1
Human
ELISA WB
HRP Conjugated
Anti-PTPN6 / SHP1 Antibody (FITC) LS-C318342

Rabbit Polyclonal (IgG) to Human PTPN6 / SHP1
Human
ELISA WB
FITC Conjugated
Anti-PTPN6 / SHP1 Antibody LS-C497783

Rabbit Monoclonal to Human PTPN6 / SHP1
Human
Flo IF IHC IP WB
Unconjugated
Anti-PTPN6 / SHP1 Antibody LS-C331469

Rabbit Polyclonal (IgG) to Human PTPN6 / SHP1
Mouse, Human
IF IHC WB
Unconjugated
Anti-PTPN6 / SHP1 Antibody (clone 1SH01) IHC-plus™ LS-B9348

Mouse Monoclonal [clone 1SH01] (IgG2b,k) to Human PTPN6 / SHP1
Human
IHC-P WB
Unconjugated
Anti-PTPN6 / SHP1 Antibody (aa553-564) IHC-plus™ LS-B7506

Goat Polyclonal to Human PTPN6 / SHP1
Mouse, Rat, Hamster, Human
ELISA IHC-P WB
Unconjugated
Anti-PTPN6 / SHP1 Antibody (phospho-Tyr536) LS-C199569

Rabbit Polyclonal (IgG) to Human PTPN6 / SHP1
Mouse, Rat, Human
ELISA IHC-P WB
Unconjugated
Anti-PTPN6 / SHP1 Antibody (phospho-Tyr564) LS-C199570

Rabbit Polyclonal (IgG) to Human PTPN6 / SHP1
Human
ELISA WB
Unconjugated
Anti-PTPN6 / SHP1 Antibody (C-Terminus) LS-C413038

Rabbit Polyclonal to Human PTPN6 / SHP1
Mouse, Rat, Human
ICC IF IHC-P WB
Unconjugated
Anti-PTPN6 / SHP1 Antibody LS-C497787

Mouse Monoclonal to Human PTPN6 / SHP1
Human
IF IHC WB
Unconjugated
Anti-PTPN6 / SHP1 Antibody LS-C401020

Rabbit Polyclonal (IgG) to Human PTPN6 / SHP1
Mouse, Rat, Human
ELISA IHC WB
Unconjugated
Anti-PTPN6 / SHP1 Antibody LS-C38617

Mouse Monoclonal (IgG1,k) to Human PTPN6 / SHP1
Human
ELISA ICC WB
Unconjugated
Anti-PTPN6 / SHP1 Antibody LS-C38618

Mouse Monoclonal (IgG2a,k) to Human PTPN6 / SHP1
Human
ELISA ICC WB
Unconjugated
Anti-PTPN6 / SHP1 Antibody LS-C38616

Mouse Monoclonal (IgG1,k) to Human PTPN6 / SHP1
Human
ELISA ICC WB
Unconjugated
Anti-PTPN6 / SHP1 Antibody LS-C131721

Mouse Monoclonal (IgG) to Human PTPN6 / SHP1
Human
ELISA ICC WB
Unconjugated
Anti-PTPN6 / SHP1 Antibody LS-C38615

Mouse Monoclonal (IgG1,k) to Human PTPN6 / SHP1
Human
ELISA ICC WB
Unconjugated
Anti-PTPN6 / SHP1 Antibody LS-C414981

Rabbit Polyclonal to Human PTPN6 / SHP1
Mouse, Rat, Human
ELISA IHC WB
Unconjugated
Anti-PTPN6 / SHP1 Antibody (aa502-551) LS-C117536

Rabbit Polyclonal (IgG) to Human PTPN6 / SHP1
Mouse, Rat, Human
ELISA IHC WB
Unconjugated
Anti-PTPN6 / SHP1 Antibody (aa480-560) LS-C386062

Rabbit Polyclonal (IgG) to Human PTPN6 / SHP1
Mouse, Rat, Human
ELISA IHC WB
Unconjugated
Anti-PTPN6 / SHP1 Antibody (phospho-Tyr536) LS-C381182

Rabbit Polyclonal (IgG) to Human PTPN6 / SHP1
Mouse, Rat, Human
ELISA IHC WB
Unconjugated
Anti-PTPN6 / SHP1 Antibody (phospho-Tyr536) LS-C336069

Rabbit Polyclonal (IgG) to Human PTPN6 / SHP1
Mouse, Rat, Human
IF IHC
Unconjugated
Anti-PTPN6 / SHP1 Antibody (aa244-515, Biotin) LS-C423185

Rabbit Polyclonal (IgG) to Human PTPN6 / SHP1
Human
ELISA ICC WB
Biotin Conjugated

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).


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