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PTPMEG / PTPN4
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
PTPMEG / PTPN4 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. This PTP has been shown to interact with glutamate receptor delta 2 and epsilon subunits, and is thought to play a role in signalling downstream of the glutamate receptors through tyrosine dephosphorylation.
| Gene Name: | protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) |
| Family/Subfamily: | Protein Phosphatase , NT5 |
| Synonyms: | PTPN4, MEG, PTPase-MEG1, PTPMEG1, PTPMEG, Megakaryocyte phosphatase, Ptp-meg1, Testis enriched phosphatase |
| Target Sequences: | NM_002830 NP_002821.1 P29074 |
Publications (1)
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