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Unfortunately, the antibody (ID:104557) is no longer available.

Below is a list of antibodies to the same protein target. You may also try your search again using the search box at the top of the page. Please contact us if you have any questions.



PTGS2 / COX2 / COX-2

prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)

Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and brain, and in pathological conditions, such as in cancer. PTGS2 is responsible for production of inflammatory prostaglandins. Up-regulation of PTGS2 is also associated with increased cell adhesion, phenotypic changes, resistance to apoptosis and tumor angiogenesis. In cancer cells, PTGS2 is a key step in the production of prostaglandin E2 (PGE2), which plays important roles in modulating motility, proliferation and resistance to apoptosis.

Gene Name: prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
Synonyms: PTGS2, COX-2, Cyclooxygenase-2, COX2, Cyclooxygenase 2b, HCox-2, GRIPGHS, PGH synthase 2, PGHS-2, PHS II, PHS-2, Prostaglandin H2 synthase 2, PGG/HS, Prostaglandin G/H synthase 2
Target Sequences: NM_000963 NP_000954.1 P35354

Publications (3)

1
Interleukin-1beta-induced cyclooxygenase-2 expression requires activation of both c-Jun NH2-terminal kinase and p38 MAPK signal pathways in rat renal mesangial cells. Guan Z, Buckman SY, Miller BW, Springer LD, Morrison AR. The Journal of biological chemistry. 1998 273:28670-6. [PubMed:9786861] Related Antibodies: LS-B410.
2
Induction of NAD(+)-linked 15-hydroxyprostaglandin dehydrogenase expression by androgens in human prostate cancer cells. Tong M, Tai HH. Biochemical and biophysical research communications. 2000 276:77-81. [PubMed:11006085] Related Antibodies: LS-B410.
3
Extracellular vesicles in luminal fluid of the ovine uterus. Burns G, Brooks K, Wildung M, Navakanitworakul R, Christenson LK, Spencer TE. PloS one. 2014 9:e90913. [Full Text Article] [PubMed:24614226] [PMC:PMC3948691] Related Antibodies: LS-C150711.

Filtered By: None
Target
ptgs2-cox2-cox-2 (103)
Reactivity
Human (95)
Mouse (36)
Rat (28)
Bovine (8)
Dog (3)
Goat (2)
Horse (2)
Monkey (1)
Pig (3)
Sheep (11)
Application
IHC (52)
IHC-Fr (4)
IHC-P (26)
WB (90)
Flo (7)
ELISA (32)
ICC (14)
IF (19)
IP (8)
Host
rabbit (68)
mouse (32)
goat (3)
Isotype
IgG (55)
IgG1 (17)
IgG1,k (8)
IgG2a (2)
IgG2b (1)
Clonality
monoclonal mc (34)
polyclonal pc (69)
Clone
10H5 (1)
13H14 (1)
1B4 (1)
2E1 (1)
2F10 (1)
3D4 (1)
4C4 (1)
4H12 (1)
5F12 (1)
6D10 (1)
9H10 (1)
CX229 (1)
RBT-COX2 (2)
SP21 (1)
Format
AP Conjugated (3)
APC Conjugated (3)
Azide-free (1)
Biotin Conjugated (6)
FITC Conjugated (10)
HRP Conjugated (3)
Magnetic beads Conjugated (1)
PE Conjugated (3)
Ready-to-Use (1)
Sepharose Conjugated (1)
Unconjugated (73)
Epitope
C-Terminus (12)
aa18-260 (8)
aa363-391 (8)
N-Terminus (5)
aa187-425 (3)
aa240-351 (3)
aa418-589 (3)
aa580-599 (2)
Thr594 (1)
aa18-604 (1)
aa26-41 (1)
aa530-610 (1)
aa554-604 (1)
aa555-604 (1)
aa578-596 (1)
aa589-604 (1)
aa592-604 (1)
Publications
No (101)
Yes (2)
Showing 1-25 out of 103 results
Anti-PTGS2 / COX2 / COX-2 Antibody (aa578-596) IHC-plus™ LS-B1608
Anti-COX-2 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1608 concentration 5 ug/ml.
Western blot of COX-2 antibody LS-B1608.

Goat Polyclonal (IgG) to Human PTGS2 / COX2 / COX-2
Mouse, Sheep, Rat, Human
ICC IHC IHC-P WB
Unconjugated
Anti-PTGS2 / COX2 / COX-2 Antibody (C-Terminus) IHC-plus™ LS-B2145
Anti-COX-2 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2145 concentration 5 ug/ml.

Rabbit Polyclonal to Rat PTGS2 / COX2 / COX-2
Mouse, Rat, Human
ELISA IHC IHC-P IP WB
Unconjugated
Anti-PTGS2 / COX2 / COX-2 Antibody (C-Terminus) IHC-plus™ LS-B410
Anti-COX-2 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B410 dilution 1:500.
Anti-Cox2 is shown to detect Cox-2 present in Cox-2 transfected Sf9 cell extract (lane 1) and IL-1b induced WISH cell extract (lane 2).  Detection occurs using a 1:10,000 dilution of antibody.

Rabbit Polyclonal to Human PTGS2 / COX2 / COX-2
Mouse, Rat, Human
ELISA IHC IHC-P WB
Unconjugated
Anti-PTGS2 / COX2 / COX-2 Antibody (C-Terminus, clone SP21) LS-C210609
Immunohistochemistry of Human colon adenocarcinoma stained with anti-COX-2 antibody
Immunohistochemistry of Human Colon stained with anti-COX-2 antibody

Rabbit Monoclonal [clone SP21] (IgG) to Rat PTGS2 / COX2 / COX-2
Human
IHC IHC-P
Unconjugated
Anti-PTGS2 / COX2 / COX-2 Antibody LS-C150711
Western blot of COX-2 antibody LS-C150711.

Rabbit Polyclonal (IgG) to Mouse PTGS2 / COX2 / COX-2
Mouse, Sheep, Rat, Human
IHC IHC-P WB
Unconjugated
Anti-PTGS2 / COX2 / COX-2 Antibody (C-Terminus) IHC-plus™ LS-B5270
Anti-COX-2 antibody IHC of human uterus, endometrium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5270 dilution 1:50.

Rabbit Polyclonal (IgG) to Rat PTGS2 / COX2 / COX-2
Mouse, Rat, Human
IHC IHC-P IP WB
Unconjugated
Anti-PTGS2 / COX2 / COX-2 Antibody (aa589-604) LS-C312879
PTGS2 / COX2 / COX-2 antibody. IHC(P): Human Intestinal Cancer Tissue.
WB of PTGS2 / COX2 / COX-2 antibody. Lane 1: Human Placenta Tissue Lysate. Lane 2: COLO320 Cell Lysate. Lane 3: HELA Cell Lysate. Lane 4: PANC Cell Lysate. Lane 5: SKOV Cell Lysate.

Rabbit Polyclonal to Human PTGS2 / COX2 / COX-2
Human
IHC IHC-Fr IHC-P WB
Unconjugated
Anti-PTGS2 / COX2 / COX-2 Antibody (aa554-604) LS-C290271
Detection of Human COX-2 by Immunohistochemistry. Sample: FFPE section of human colon carcinoma. Antibody: Affinity purified rabbit anti-COX-2 used at a dilution of 1:1000 (1 ug/ml). Detection: DAB.
Detection of Human COX-2 by Immunohistochemistry. Sample: FFPE section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti-COX-2 used at a dilution of 1:1000 (1 ug/ml). Detection: DAB.

Rabbit Polyclonal (IgG) to Human PTGS2 / COX2 / COX-2
Goat, Dog, Sheep, Bovine, Pig, Human
IF IHC IHC-P IP WB
Unconjugated
Anti-PTGS2 / COX2 / COX-2 Antibody (C-Terminus) IHC-plus™ LS-B13123
Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
Immunofluorescent analysis of PGHS-2 staining in Jurkat cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).

Rabbit Polyclonal to Human PTGS2 / COX2 / COX-2
Mouse, Sheep, Bovine, Rat, Pig, Human
ICC IF IHC IHC-P WB
Unconjugated
Anti-PTGS2 / COX2 / COX-2 Antibody (aa592-604) LS-C20148
Immunofluorescence analysis of paraformaldehyde fixed HepG2 cells, permeabilized with 0.15% Triton. Primary incubation 1hr (10ug/ml) followed by Alexa Fluor 488 secondary antibody (2ug/ml), showing cytoplasmic/vesicle staining. The nuclear stain i
Immunofluorescence analysis of paraformaldehyde fixed NIH3T3 cells, permeabilized with 0.15% Triton. Primary incubation 1hr (10ug/ml) followed by Alexa Fluor 488 secondary antibody (2ug/ml), showing cytoplasm and vesicle staining. The nuclear sta

Goat Polyclonal to Human PTGS2 / COX2 / COX-2
Dog, Sheep, Bovine, Pig, Horse, Human, Monkey
ELISA WB
Unconjugated
Anti-PTGS2 / COX2 / COX-2 Antibody IHC-plus™ LS-B5206
Anti-COX-2 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5206 concentration 10 ug/ml.

Rabbit Polyclonal (IgG) to Rat PTGS2 / COX2 / COX-2
Mouse, Rat, Human
IHC IHC-P IP WB
Unconjugated
Anti-PTGS2 / COX2 / COX-2 Antibody (aa580-599, FITC) LS-C22388

Mouse Monoclonal (IgG1) to Human PTGS2 / COX2 / COX-2
Human
Flo
FITC Conjugated
Anti-PTGS2 / COX2 / COX-2 Antibody (aa363-391) LS-C162280
PTGS2 Antibody (Center P378) immunohistochemistry of formalin-fixed and paraffin-embedded human uterus tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
Confocal immunofluorescence of PTGS2 Antibody (Center P378) with A549 cell followed by Alexa Fluor 489-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).

Rabbit Polyclonal to Human PTGS2 / COX2 / COX-2
Human
IF IHC IHC-P WB
Unconjugated
Anti-PTGS2 / COX2 / COX-2 Antibody LS-C150715
Western blot of COX-2 antibody LS-C150715.

Rabbit Polyclonal (IgG) to Mouse PTGS2 / COX2 / COX-2
Mouse
ICC IHC IHC-P WB
Unconjugated
Anti-PTGS2 / COX2 / COX-2 Antibody (aa18-260, clone 5F12) LS-C339530
IHC of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-PTGS2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).
IHC of paraffin-embedded Carcinoma of Human pancreas tissue using anti-PTGS2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).

Mouse Monoclonal [clone 5F12] (IgG2b) to Human PTGS2 / COX2 / COX-2
Human
IHC IHC-P WB
Unconjugated
Anti-PTGS2 / COX2 / COX-2 Antibody (FITC) LS-C150699

Rabbit Polyclonal (IgG) to Mouse PTGS2 / COX2 / COX-2
Mouse, Rat, Human
Flo IF WB
FITC Conjugated
Anti-PTGS2 / COX2 / COX-2 Antibody (C-Terminus) LS-C79822

Rabbit Polyclonal (IgG) to Rat PTGS2 / COX2 / COX-2
Mouse, Rat, Human
IHC IHC-Fr IHC-P IP WB
Unconjugated
Anti-PTGS2 / COX2 / COX-2 Antibody (clone RBT-COX2) LS-C312016
IHC of COX-2 on FFPE Colon Adenocarcinoma tissue.

Rabbit Monoclonal [clone RBT-COX2] (IgG) to Human PTGS2 / COX2 / COX-2
Human
IHC IHC-Fr IHC-P
Unconjugated
Anti-PTGS2 / COX2 / COX-2 Antibody (clone RBT-COX2, Ready-to-Use) LS-C348414
IHC of COX-2 on FFPE Colon Adenocarcinoma tissue. This image was taken for the unmodified form of this product. Other forms have not been tested.

Rabbit Monoclonal [clone RBT-COX2] (IgG) to Human PTGS2 / COX2 / COX-2
Human
IHC IHC-Fr IHC-P
Unconjugated, Ready-to-Use
Anti-PTGS2 / COX2 / COX-2 Antibody (aa555-604) LS-C118419
IHC of paraffin-embedded human breast carcinoma tissue, using Cox2 Antibody. The picture on the right is treated with the synthesized peptide.
Immunofluorescence of A549 cells, using Cox2 Antibody. The picture on the right is treated with the synthesized peptide.

Rabbit Polyclonal (IgG) to Human PTGS2 / COX2 / COX-2
Human
ELISA IF IHC IHC-P WB
Unconjugated
Anti-PTGS2 / COX2 / COX-2 Antibody LS-C417692
Western blot of Cox2 expression in A549 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.

Rabbit Polyclonal to Human PTGS2 / COX2 / COX-2
Mouse, Rat, Human
ICC IF IHC WB
Unconjugated
Anti-PTGS2 / COX2 / COX-2 Antibody (aa363-391, Biotin) LS-C267494

Rabbit Polyclonal (IgG) to Human PTGS2 / COX2 / COX-2
Human
ELISA ICC IF IHC WB
Biotin Conjugated
Anti-PTGS2 / COX2 / COX-2 Antibody (aa363-391, AP) LS-C267492

Rabbit Polyclonal (IgG) to Human PTGS2 / COX2 / COX-2
Human
ELISA ICC IF IHC WB
AP Conjugated
Anti-PTGS2 / COX2 / COX-2 Antibody (aa363-391, APC) LS-C267495

Rabbit Polyclonal (IgG) to Human PTGS2 / COX2 / COX-2
Human
ELISA ICC IF IHC WB
APC Conjugated
Anti-PTGS2 / COX2 / COX-2 Antibody (aa363-391, PE) LS-C267496

Rabbit Polyclonal (IgG) to Human PTGS2 / COX2 / COX-2
Human
ELISA ICC IF IHC WB
PE Conjugated

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PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).


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