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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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PTGS1 / COX-1

prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)

Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Involved in the constitutive production of prostanoids in particular in the stomach and platelets. In gastric epithelial cells, it is a key step in the generation of prostaglandins, such as prostaglandin E2 (PGE2), which plays an important role in cytoprotection. In platelets, it is involved in the generation of thromboxane A2 (TXA2), which promotes platelet activation and aggregation, vasoconstriction and proliferation of vascular smooth muscle cells.

Gene Name: prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
Synonyms: PTGS1, COX1, Cyclooxygenase-1, COX-1, PES-1, PGH synthase 1, Prostaglandin G/H synthase 1, PTGHS, COX3, PCOX1, PGG/HS, PGHS-1, PGHS1, PHS 1, PHS1, Prostaglandin H2 synthase 1
Target Sequences: NM_000962 NP_000953.2 P23219

Publications (1)

1
Inhibition of Pro-inflammatory and Anti-apoptotic Biomarkers during Experimental Oral Cancer Chemoprevention by Dietary Black Raspberries. Oghumu S, Casto BC, Ahn-Jarvis J, Weghorst LC, Maloney J, Geuy P, Horvath KZ, Bollinger CE, Warner BM, Summersgill KF, Weghorst CM, Knobloch TJ. Frontiers in immunology. 2017 October;8:1325. [Full Text Article] [PubMed:29109723] [PMC:PMC5660285]

Viewing 1-25 of 107 items
PTGS1 / COX-1 Antibody - Anti-PTGS1 / COX-1 antibody IHC of human vessel. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Select
Neuroscience
Rabbit Polyclonal (IgG) to Human PTGS1 / COX-1
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50µl   1mg/ml   $425.00
PTGS1 / COX-1 Antibody - Anti-COX-1 antibody IHC of human skin, epidermis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5 ug/ml.
Select
Neuroscience
Rabbit Polyclonal to Human PTGS1 / COX-1
Human
IHC, IHC-P
Unconjugated
250µl   $555.00
PTGS1 / COX-1 Antibody - Anti-PTGS1 / COX-1 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.
Select
Goat Polyclonal to Human PTGS1 / COX-1
Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50µg   0.5mg/ml   $425.00
PTGS1 / COX-1 Antibody - Anti-PTGS1 / COX1 / COX-1 antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Rabbit Polyclonal (IgG) to Mouse PTGS1 / COX-1
Mouse, Rat, Human
IHC, IHC-P, IP, WB
Unconjugated
50µg   250µl   0.2mg/ml   $555.00
PTGS1 / COX-1 Antibody - Anti-PTGS1 / COX-1 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 15 ug/ml.
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Rabbit Polyclonal to Human PTGS1 / COX-1
Human
IHC, IHC-P
Unconjugated
500µl   0.1mg/ml   $425.00
PTGS1 / COX-1 Antibody - Anti-PTGS1 / COX-1 antibody IHC of human brain. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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Rabbit Polyclonal to Human PTGS1 / COX-1
Human
IHC, IHC-P, WB
Unconjugated
100µl   0.68mg/ml   $485.00
Select
Mouse Monoclonal (IgG2b) to Human PTGS1 / COX-1
Rabbit, Guinea pig, Sheep, Bovine, Human
ELISA, IHC
Unconjugated
1ml   $485.00
Select
Mouse Monoclonal (IgG2b,k) to Human PTGS1 / COX-1
Mouse, Sheep, Rat, Human
ELISA, IF, IHC, IHC-Fr, IHC-P, WB
Unconjugated
100µg   $635.00
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Mouse Monoclonal (IgG2b,k) to Human PTGS1 / COX-1
Mouse, Sheep, Rat, Human
ELISA, IF, IHC, WB
HRP Conjugated
100µl   $815.00
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Mouse Monoclonal (IgG2b,k) to Human PTGS1 / COX-1
Mouse, Sheep, Rat, Human
ELISA, IF, IHC, WB
Biotin Conjugated
100µl   $815.00
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Mouse Monoclonal (IgG2b,k) to Human PTGS1 / COX-1
Mouse, Sheep, Rat, Human
ELISA, IF, IHC, WB
FITC Conjugated
100µl   $815.00
Select
Mouse Monoclonal (IgG2b,k) to Human PTGS1 / COX-1
Mouse, Sheep, Rat, Human
ELISA, IF, IHC, WB
AP Conjugated
100µl   $815.00
Select
Mouse Monoclonal (IgG2b,k) to Human PTGS1 / COX-1
Mouse, Sheep, Rat, Human
ELISA, IF, IHC, WB
PE Conjugated
100µl   $815.00
Select
Mouse Monoclonal (IgG2b,k) to Human PTGS1 / COX-1
Mouse, Sheep, Rat, Human
ELISA, IF, IHC, WB
APC Conjugated
100µl   $815.00
PTGS1 / COX-1 Antibody - PTGS1 / COX1 / COX-1 antibody. IHC(P): Human Intestinal Cancer Tissue.
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Rabbit Polyclonal to Human PTGS1 / COX-1
Rat, Human
IHC, IHC-P, WB
Unconjugated
100µg   200µl   0.5mg/ml   $325.00
Select
Mouse Monoclonal [clone CX111] (IgG2b) to Human PTGS1 / COX-1
Mouse, Sheep, Bovine, Rat, Human
Flo, IF
PE Conjugated
1ea   $365.00
Select
Rabbit Polyclonal (IgG) to Mouse PTGS1 / COX-1
Mouse, Dog, Human
ELISA, WB
Unconjugated
100µg   $755.00
PTGS1 / COX-1 Antibody
Select
Rabbit Polyclonal (IgG) to Human PTGS1 / COX-1
Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100µl   1mg/ml   $325.00; 200µl   1mg/ml   $375.00
PTGS1 / COX-1 Antibody - Immunocytochemistry/Immunofluorescence analysis using Rabbit Anti-Cyclooxygenase 1 Polyclonal Antibody. Tissue: Colon carcinoma cell line (RKO). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Rabbit Anti-Cyclooxygenase 1 Polyclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Rabbit ATTO 488 at 1:100 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60 min at RT, 5 min at RT. Localization: Microsome Membrane, Endoplasmic Reticulum Membrane, Membrane. Magnification: 60X. (A) DAPI nuclear stain. (B) Phalloidin Texas Red F-Actin stain. (C) Cyclooxygenase 1 Antibody. (D) Composite.
Select
Rabbit Polyclonal to Human PTGS1 / COX-1
Mouse, Rat, Human
IF, WB
Unconjugated
100µg   1mg/ml   $365.00
Select
Rabbit Polyclonal to Human PTGS1 / COX-1
Sheep, Bovine, Horse, Human
ICC, IHC, WB
Unconjugated
200µl   $605.00
Select
Rabbit Polyclonal (IgG) to Mouse PTGS1 / COX-1
Mouse, Rat, Human
IHC, IP, WB
Unconjugated
100µg   $495.00
Select
Rabbit Polyclonal (IgG) to Mouse PTGS1 / COX-1
Mouse, Rat, Human
IHC, IP, WB
Unconjugated
100µg   $755.00
Select
Rabbit Polyclonal (IgG) to Human PTGS1 / COX-1
Human
ELISA, IHC, WB
Unconjugated
100µg   $335.00
PTGS1 / COX-1 Antibody - Western blot of Cox-1 antibody
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Rabbit Polyclonal (IgG) to Human PTGS1 / COX-1
Human
ELISA, IHC, WB
Unconjugated
50µl   1mg/ml   $235.00; 100µl   1mg/ml   $265.00; 200µl   1mg/ml   $335.00
PTGS1 / COX-1 Antibody - Immunocytochemistry/Immunofluorescence analysis using Rabbit Anti-Cyclooxygenase 1 Polyclonal Antibody. Tissue: Colon carcinoma cell line (RKO). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Rabbit Anti-Cyclooxygenase 1 Polyclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Rabbit ATTO 488 at 1:100 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60 min at RT, 5 min at RT. Localization: Microsome Membrane, Endoplasmic Reticulum Membrane, Membrane. Magnification: 60X. (A) DAPI nuclear stain. (B) Phalloidin Texas Red F-Actin stain. (C) Cyclooxygenase 1 Antibody. (D) Composite.
Select
Rabbit Polyclonal to Human PTGS1 / COX-1
Mouse, Rat, Human
IF, WB
Biotin Conjugated
100µg   1mg/ml   $395.00

Viewing 1-25 of 107 items


If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).