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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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PTGS1 / COX-1

prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)

Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Involved in the constitutive production of prostanoids in particular in the stomach and platelets. In gastric epithelial cells, it is a key step in the generation of prostaglandins, such as prostaglandin E2 (PGE2), which plays an important role in cytoprotection. In platelets, it is involved in the generation of thromboxane A2 (TXA2), which promotes platelet activation and aggregation, vasoconstriction and proliferation of vascular smooth muscle cells.

Gene Name: prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
Synonyms: PTGS1, COX1, Cyclooxygenase-1, COX-1, PES-1, PGH synthase 1, Prostaglandin G/H synthase 1, PTGHS, COX3, PCOX1, PGG/HS, PGHS-1, PGHS1, PHS 1, PHS1, Prostaglandin H2 synthase 1
Target Sequences: NM_000962 NP_000953.2 P23219

Filtered By: None
Target
PTGS1 / COX-1 (100)
Reactivity
Human (73)
Mouse (49)
Rat (33)
Bat (4)
Bovine (8)
Chimpanzee (6)
Dog (1)
Gibbon (6)
Guinea pig (1)
Horse (5)
Mammal (3)
Monkey (9)
Pig (8)
Rabbit (1)
Rodent (2)
Sheep (21)
Zebrafish (4)
Application
IHC (60)
IHC-Fr (1)
IHC-P (14)
WB (85)
Flo (2)
ELISA (27)
ICC (3)
IF (10)
IP (6)
Peptide-ELISA (2)
Host
rabbit (76)
mouse (20)
goat (4)
Isotype
IgG (67)
IgG1 (9)
IgG2b (2)
IgG2b,k (7)
Clonality
monoclonal mc (19)
polyclonal pc (81)
Clone
CX111 (2)
Format
AP Conjugated (3)
APC (3)
APC Conjugated (6)
Biotin Conjugated (11)
Cy3 Conjugated (3)
Cy7 Conjugated (3)
FITC Conjugated (12)
HRP Conjugated (8)
Magnetic beads Conjugated (1)
PE Conjugated (7)
Sepharose Conjugated (1)
Unconjugated (45)
Epitope
aa23-277 (10)
aa367-599 (10)
aa407-602 (10)
N-Terminus (5)
aa218-267 (4)
aa51-100 (4)
C-Terminus (2)
520-600 aa, C-terminal (1)
Ser585 (1)
aa272-282 (1)
aa274-288 (1)
aa318-599 (1)
aa55-66 (1)
aa550-599 (1)
aa586 (1)
aa617-630 (1)
Publications
No (100)
Showing 1-25 of 100 results

PTGS1 / COX-1 Antibody IHC-plus™ LS-B8734
Rabbit Polyclonal (IgG) to Mouse PTGS1 / COX-1
Mouse, Rat, Human
IHC IHC-P IP WB
Unconjugated
50µg 250µl 0.2mg/ml  $425.00
Anti-PTGS1 / COX1 / COX-1 antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-PTGS1 / COX1 / COX-1 antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

PTGS1 / COX-1 Antibody LS-C14622
Mouse Monoclonal (IgG2b) to Human PTGS1 / COX-1
Rabbit, Guinea pig, Sheep, Bovine, Human
ELISA IHC
Unconjugated
1000µl  $455.00

PTGS1 / COX-1 Antibody LS-C14603
Mouse Monoclonal (IgG2b,k) to Human PTGS1 / COX-1
Mouse, Sheep, Rat, Human
ELISA IF IHC IHC-Fr IHC-P WB
Unconjugated
100µg 0.5mg/ml  $605.00

PTGS1 / COX-1 Antibody (HRP) LS-C545315
Mouse Monoclonal (IgG2b,k) to Human PTGS1 / COX-1
Mouse, Sheep, Rat, Human
ELISA IF IHC WB
HRP Conjugated
100µl  $800.00

PTGS1 / COX-1 Antibody (Biotin) LS-C525195
Mouse Monoclonal (IgG2b,k) to Human PTGS1 / COX-1
Mouse, Sheep, Rat, Human
ELISA IF IHC WB
Biotin Conjugated
100µl  $800.00

PTGS1 / COX-1 Antibody (FITC) LS-C535212
Mouse Monoclonal (IgG2b,k) to Human PTGS1 / COX-1
Mouse, Sheep, Rat, Human
ELISA IF IHC WB
FITC Conjugated
100µl  $800.00

PTGS1 / COX-1 Antibody (AP) LS-C507232
Mouse Monoclonal (IgG2b,k) to Human PTGS1 / COX-1
Mouse, Sheep, Rat, Human
ELISA IF IHC WB
AP Conjugated
100µl  $800.00

PTGS1 / COX-1 Antibody (APC) LS-C516145
Mouse Monoclonal (IgG2b,k) to Human PTGS1 / COX-1
Mouse, Sheep, Rat, Human
ELISA IF IHC WB
APC Conjugated
100µl  $800.00

PTGS1 / COX-1 Antibody (PE) LS-C653399
Mouse Monoclonal (IgG2b,k) to Human PTGS1 / COX-1
Mouse, Sheep, Rat, Human
ELISA IF IHC WB
PE Conjugated
100µl  $800.00

PTGS1 / COX-1 Antibody (aa617-630) IHC-plus™ LS-B3229
Goat Polyclonal to Human PTGS1 / COX-1
Human
IF IHC IHC-P Peptide-ELISA WB
Unconjugated
50µg 0.5mg/ml  $425.00
Anti-PTGS1 / COX-1 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.
Immunofluorescence analysis of paraformaldehyde fixed NIH3T3 cells, permeabilized with 0.15% Triton. Primary incubation 1hr (5ug/ml) followed by Alexa Fluor 488 secondary antibody (2ug/ml), showing Golgi and vesicle staining. The nuclear stain is
Anti-PTGS1 / COX-1 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.
Immunofluorescence analysis of paraformaldehyde fixed NIH3T3 cells, permeabilized with 0.15% Triton. Primary incubation 1hr (5ug/ml) followed by Alexa Fluor 488 secondary antibody (2ug/ml), showing Golgi and vesicle staining. The nuclear stain is

PTGS1 / COX-1 Antibody (C-Terminus) IHC-plus™ LS-B3369
Rabbit Polyclonal to Human PTGS1 / COX-1
Human
IHC IHC-P
Unconjugated
500µl 0.1mg/ml  $425.00
Anti-PTGS1 / COX-1 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 15 ug/ml.
Anti-PTGS1 / COX-1 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 15 ug/ml.
Anti-PTGS1 / COX-1 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 15 ug/ml.
Anti-PTGS1 / COX-1 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 15 ug/ml.

PTGS1 / COX-1 Antibody (N-Terminus) LS-C14629
Rabbit Polyclonal (IgG) to Mouse PTGS1 / COX-1
Mouse, Dog, Human
ELISA WB
Unconjugated
100µg 100µl 1mg/ml  $755.00

PTGS1 / COX-1 Antibody (aa550-599) IHC-plus™ LS-B7596
Rabbit Polyclonal (IgG) to Human PTGS1 / COX-1
Human
IHC IHC-P Peptide-ELISA WB
Unconjugated
50µl 1mg/ml  $425.00
Anti-PTGS1 / COX-1 antibody IHC of human vessel. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Western blot analysis of lysates from HUVEC cells, using Cox1 Antibody. The lane on the right is blocked with the synthesized peptide.
Anti-PTGS1 / COX-1 antibody IHC of human vessel. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Western blot analysis of lysates from HUVEC cells, using Cox1 Antibody. The lane on the right is blocked with the synthesized peptide.

PTGS1 / COX-1 Antibody IHC-plus™ LS-B8640
Rabbit Polyclonal to Human PTGS1 / COX-1
Human
IHC IHC-P
Unconjugated
250µl  $555.00
Anti-COX-1 antibody IHC of human skin, epidermis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5 ug/ml.
Anti-COX-1 antibody IHC of human skin, epidermis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5 ug/ml.

PTGS1 / COX-1 Antibody IHC-plus™ LS-B4791
Rabbit Polyclonal to Human PTGS1 / COX-1
Human
IHC IHC-P WB
Unconjugated
100µl 0.68mg/ml  $425.00
Anti-PTGS1 / COX-1 antibody IHC of human brain. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-PTGS1 / COX-1 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-PTGS1 / COX-1 antibody IHC of human brain. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-PTGS1 / COX-1 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

PTGS1 / COX-1 Antibody (aa318-599) LS-C313396
Rabbit Polyclonal to Human PTGS1 / COX-1
Rat, Human
IHC IHC-P WB
Unconjugated
100µg 200µl 0.5mg/ml  $325.00
PTGS1 / COX1 / COX-1 antibody. IHC(P): Human Intestinal Cancer Tissue.
PTGS1 / COX1 / COX-1 antibody. IHC(P): Human Lung Cancer Tissue.
PTGS1 / COX1 / COX-1 antibody. IHC(P): Human Intestinal Cancer Tissue.
PTGS1 / COX1 / COX-1 antibody. IHC(P): Human Lung Cancer Tissue.

PTGS1 / COX-1 Antibody (aa272-282) LS-C14610
Rabbit Polyclonal to Human PTGS1 / COX-1
Sheep, Bovine, Horse, Human
ICC IHC WB
Unconjugated
200µl  $605.00

PTGS1 / COX-1 Antibody LS-C753161
Rabbit Polyclonal (IgG) to Human PTGS1 / COX-1
Human
ELISA IHC WB
Unconjugated
100µg  $335.00

PTGS1 / COX-1 Antibody (aa586) LS-C190191
Rabbit Polyclonal (IgG) to Mouse PTGS1 / COX-1
Mouse, Rat, Human
IHC IP WB
Unconjugated
100µg 0.1mg/ml  $495.00

PTGS1 / COX-1 Antibody LS-C194983
Rabbit Polyclonal (IgG) to Mouse PTGS1 / COX-1
Mouse, Rat, Human
IHC IP WB
Unconjugated
100µg 0.2mg/ml  $755.00

PTGS1 / COX-1 Antibody (520-600 aa, C-terminal) LS-C382873
Rabbit Polyclonal (IgG) to Human PTGS1 / COX-1
Human
ELISA IHC WB
Unconjugated
100µl 1mg/ml  $265.00
Western blot of Cox-1 antibody
Western blot of Cox-1 antibody

PTGS1 / COX-1 Antibody (aa274-288) LS-C14609
Rabbit Polyclonal to Mouse PTGS1 / COX-1
Mouse
IHC WB
Unconjugated
200µg 200µl  $465.00

PTGS1 / COX-1 Antibody LS-C150707
Rabbit Polyclonal (IgG) to Mouse PTGS1 / COX-1
Mouse, Rat
IHC WB
Unconjugated
1ea  $345.00
Western blot of COX-1 antibody.
Western blot of COX-1 antibody.

PTGS1 / COX-1 Antibody (aa407-602) LS-C296073
Rabbit Polyclonal (IgG) to Mouse PTGS1 / COX-1
Mouse
IHC WB
Unconjugated
20µl 0.5mg/ml  $195.00; 100µl 0.5mg/ml  $255.00; 200µl 0.5mg/ml  $285.00; 1ml 0.5mg/ml  $485.00; 10ml 0.5mg/ml  $1,935.00
Western blot of recombinant PTGS1 / COX1 / COX-1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of recombinant PTGS1 / COX1 / COX-1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

PTGS1 / COX-1 Antibody LS-C14612
Goat Polyclonal (IgG) to Sheep PTGS1 / COX-1
Sheep, Mammal, Rodent
ELISA IHC WB
Unconjugated
100µl  $435.00
Showing 1-25 of 100 results

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If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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