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PTGR2 / PGR2

prostaglandin reductase 2

Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-keto-PGE1, 15-keto-PGE2, 15-keto-PGE1-alpha and 15-keto-PGE2-alpha with highest activity towards 15-keto-PGE2. Overexpression represses transcriptional activity of PPARG and inhibits adipocyte differentiation.

Gene Name:	prostaglandin reductase 2
Synonyms:	PTGR2, PGR2, Prostaglandin reductase 2, PRG-2, ZADH1
Target Sequences:	AA443151 NP_689657.1 Q8N8N7

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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