PTF1A

pancreas specific transcription factor, 1a

Transcription factor implicated in the cell fate determination in various organs. Binds to the E-box consensus sequence 5'-CANNTG-3'. Plays a role in early and late pancreas development and differentiation. Important for determining whether cells allocated to the pancreatic buds continue towards pancreatic organogenesis or revert back to duodenal fates. May be involved in the maintenance of exocrine pancreas-specific gene expression including ELA1 and amylase. Required for the formation of pancreatic acinar and ductal cells. Plays an important role in cerebellar development. Directly regulated by FOXN4 and RORC during retinal development, FOXN4-PTF1A pathway plays a central role in directing the differentiation of retinal progenitors towards horizontal and amacrine fates.

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Proteins (5)

Type

Over-Expression Lysate (2)

Recombinant (3)

Target

PTF1A (5)

Publications

No (5)

Tag

His (1)

His, N-Terminal (1)

His-GST (1)

Myc-DDK (Flag) (2)

Species

Human (4)

Source

293T Cells (1)

E. coli (3)

HEK 293 Cells (1)

Purification

Purified (1)

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Human PTF1A Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G93008

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

34.8 kDa

Price:

20 µg/$150

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Human PTF1A Protein (Recombinant His) (aa177-328) - LS-G15035

Source:

E. coli

Tag:

His

Molecular Weight:

17.9 kDa

Price:

10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,841

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Human PTF1A Protein (Recombinant His-GST) (aa177-328) - LS-G15040

Source:

E. coli

Tag:

His-GST

Molecular Weight:

43.4 kDa

Price:

10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,841

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PTF1A Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G104750

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

34.8 kDa

Price:

100 µg/$494

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Human PTF1A Protein (Recombinant His, N-Terminal) (Ala48-Pro115) - LS-G133010

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

8.3kDa

Price:

10 µg/$267; 50 µg/$352; 200 µg/$702; 100 µg/$562; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,838

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