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Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) or phosphatidylcholine (PC) is replaced by L-serine. In membranes, PTDSS1 catalyzes mainly the conversion of phosphatidylcholine. Also converts, in vitro and to a lesser extent, phosphatidylethanolamine.
Gene Name: | phosphatidylserine synthase 1 |
Synonyms: | PTDSS1, KIAA0024, PSSA, PtdSer synthase 1, PSS-1, PSS1, Serine-exchange enzyme I, Phosphatidylserine synthase 1, Phosphatidylserine synthase I |
Target Sequences: | NM_014754 NP_055569.1 P48651 |
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