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PTAFR / PAF Receptor

platelet-activating factor receptor

PTAFR / PAF Receptor is a seven-transmembrane G-protein-coupled receptor for platelet-activating factor (PAF) that localizes to lipid rafts and/or caveolae in the cell membrane. PAF (1-0-alkyl-2-acetyl-sn-glycero-3-phosphorylcholine) is a phospholipid that plays a significant role in oncogenic transformation, tumor growth, angiogenesis, metastasis, and pro-inflammatory processes. Binding of PAF to the PAF-receptor (PAFR) stimulates numerous signal transduction pathways including phospholipase C, D, A2, mitogen-activated protein kinases (MAPKs), and the phosphatidylinositol-calcium second messenger system. Following PAFR activation, cells become rapidly desensitized and this refractory state is dependent on PAFR phosphorylation, internalization, and down-regulation. Alternative splicing results in multiple transcript variants.

Gene Name: platelet-activating factor receptor
Family/Subfamily: GPCR , Platelet activating factor
Synonyms: PTAFR, PAF-R, PAF receptor, PAFR, R-PAF
Target Sequences: NM_000952 NP_000943.1 P25105

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Products
ELISA Kits (3)
Competitive EIA (1)
Sandwich (2)
PTAFR / PAF Receptor (3)
Human (2)
Rat (1)
96-Well Strip Plate (3)
No (3)
Cell Lysates (2)
Plasma (1)
Serum (1)
Tissue Homogenates (2)
PTAFR / PAF Receptor ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$834
PTAFR / PAF Receptor ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$893
PTAFR / PAF Receptor ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Human
2.5 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).