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Unfortunately, the antibody (ID:90803) is no longer available.

Below is a list of antibodies to the same protein target. You may also try your search again using the search box at the top of the page. Please contact us if you have any questions.



PSME4 / PA200

proteasome (prosome, macropain) activator subunit 4

Associated component of the proteasome that specifically recognizes acetylated histones and promotes ATP- and ubiquitin-independent degradation of core histones during spermatogenesis and DNA damage response. Recognizes and binds acetylated histones via its bromodomain-like (BRDL) region and activates the proteasome by opening the gated channel for substrate entry. Binds to the core proteasome via its C-terminus, which occupies the same binding sites as the proteasomal ATPases, opening the closed structure of the proteasome via an active gating mechanism. Component of the spermatoproteasome, a form of the proteasome specifically found in testis: binds to acetylated histones and promotes degradation of histones, thereby participating actively to the exchange of histones during spermatogenesis. Also involved in DNA damage response in somatic cells, by promoting degradation of histones following DNA double-strand breaks.

Gene Name: proteasome (prosome, macropain) activator subunit 4
Synonyms: PSME4, KIAA0077, Proteasome activator 200 kDa, PA200, Proteasome activator PA200
Target Sequences: D38521 BAA07526.1 Q14997

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Target Reactivity Applications Host Isotype Clonality Clone Format Epitope Publications Type
PSME4 / PA200 Rabbit Polyclonal Unconjugated Human WB, ELISA aa503-535
1
PSME4 / PA200 Rabbit Polyclonal Unconjugated Human WB, ELISA aa503-535 No Primary
Anti-PSME4 / PA200 Antibody (aa503-535) LS-C393102
Western blot Image
Rabbit Polyclonal to Human PSME4 / PA200
Human
Western blot, ELISA
Unconjugated
PSME4 / PA200 Rabbit IgG Polyclonal Unconjugated Human WB, IP aa1-50
1
PSME4 / PA200 Rabbit IgG Polyclonal Unconjugated Human WB, IP aa1-50 No Primary
Anti-PSME4 / PA200 Antibody (aa1-50) LS-C290526
Western blot Image
Western blot Image
Rabbit Polyclonal (IgG) to Human PSME4 / PA200
Human
Western blot, Immunoprecipitation
Unconjugated

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).


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