PSMD8 / RPN12

proteasome (prosome, macropain) 26S subunit, non-ATPase, 8

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 1.

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Products

Antibodies (9)

Type

Primary (9)

Target

PSMD8 / RPN12 (9)

Reactivity

Human (9)

Mouse (6)

Rat (4)

Bat (3)

Bovine (3)

Chimpanzee (3)

Dog (3)

Gibbon (3)

Guinea pig (3)

Horse (3)

Monkey (3)

Orangutan (3)

Pig (3)

Rabbit (3)

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Application

IHC (5)

IHC-P (2)

WB (8)

ELISA (1)

ICC (1)

IF (3)

Host

rabbit (8)

mouse (1)

Isotype

IgG (7)

IgG1 (1)

Clonality

monoclonal mc (1)

polyclonal pc (8)

Clone

p31-27 (1)

Format

Biotin Conjugated (1)

FITC Conjugated (1)

HRP Conjugated (1)

Unconjugated (6)

Epitope

C-Terminus (4)

Publications

No (9)

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PSMD8 / RPN12 Antibody (clone p31-27) LS-C343792

Antibody:

PSMD8 / RPN12 Mouse anti-Human Monoclonal (p31-27) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

100 µl/$599

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PSMD8 / RPN12 Antibody LS-C482732

Antibody:

PSMD8 / RPN12 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ICC, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$286; 100 µl/$321; 200 µl/$386

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PSMD8 / RPN12 Antibody LS-C346379

Antibody:

PSMD8 / RPN12 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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PSMD8 / RPN12 Antibody LS-C769934

Antibody:

PSMD8 / RPN12 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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PSMD8 / RPN12 Antibody LS-C676325

Antibody:

PSMD8 / RPN12 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

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PSMD8 / RPN12 Antibody (C-Terminus) LS-C81185

Antibody:

PSMD8 / RPN12 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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PSMD8 / RPN12 Antibody (C-Terminus, HRP) LS-C450924

Antibody:

PSMD8 / RPN12 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody

Reactivity:

Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

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PSMD8 / RPN12 Antibody (C-Terminus, Biotin) LS-C450900

Antibody:

PSMD8 / RPN12 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody

Reactivity:

Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

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PSMD8 / RPN12 Antibody (C-Terminus, FITC) LS-C450923

Antibody:

PSMD8 / RPN12 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody

Reactivity:

Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

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