PSMC6

proteasome (prosome, macropain) 26S subunit, ATPase, 6

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. Pseudogenes have been identified on chromosomes 8 and 12.

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Products

Proteins (10)

Type

Over-Expression Lysate (4)

Recombinant (6)

Target

PSMC6 (10)

Publications

No (10)

Tag

GST (2)

GST, N-terminus (1)

His, N-Terminal (1)

His-T7 (1)

Myc-DDK (Flag) (5)

Species

Human (8)

Source

293T Cells (2)

E. coli (2)

HEK 293 Cells (3)

Wheat Germ Extract (3)

Purification

Purified (2)

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PSMC6 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G128956

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

45.6 kDa

Price:

100 µg/$494

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Human PSMC6 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G64729

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

44 kDa

Price:

20 µg/$1,107

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Human PSMC6 Protein (Recombinant His, N-Terminal) - LS-G144998

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

44 kDa

Price:

50 µg/$419

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Human PSMC6 Protein (Recombinant GST) (Full Length) - LS-G29990

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

68.31 kDa

Price:

10 µg/$479; 25 µg/$670

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Human PSMC6 Protein (Recombinant GST) (Full Length) - LS-G29991

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

70.6 kDa

Price:

10 µg/$479; 25 µg/$670

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Human PSMC6 Protein (Recombinant GST, N-terminus) (aa290-389) - LS-G59790

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human PSMC6 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G74021

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

44 kDa

Price:

20 µg/$150

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Human PSMC6 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G74022

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

45.6 kDa

Price:

20 µg/$150

Select

PSMC6 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99878

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

44 kDa

Price:

100 µg/$494

Select

Human PSMC6 Protein (Recombinant His-T7) (aa2-403) - LS-G15723

Source:

E. coli

Tag:

His-T7

Molecular Weight:

49.5 kDa

Price:

10 µg/$276; 50 µg/$412; 100 µg/$657; 200 µg/$822; 1 mg/$1,905; 500 µg/$1,455; 5 mg/$2,871; 2 mg/$2,090

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