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PSMC5 / SUG1

proteasome (prosome, macropain) 26S subunit, ATPase, 5

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. In addition to participation in proteasome functions, this subunit may participate in transcriptional regulation since it has been shown to interact with the thyroid hormone receptor and retinoid X receptor-alpha. Two transcript variants encoding different isoforms have been found for this gene.

Gene Name: proteasome (prosome, macropain) 26S subunit, ATPase, 5
Family/Subfamily: ATPase , not assigned-ATPase
Synonyms: PSMC5, p45, S8, Tat-binding protein homolog 10, SUG-1, MSUG1 protein, Thyroid receptor interactor 1, SUG1, TBP10, p45/SUG, Proteasome subunit p45, TRIP1
Target Sequences: NM_002805 NP_002796.4 P62195

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Products
Antibodies (25)
Primary (25)
PSMC5 / SUG1 (25)
Human (25)
Mouse (20)
Rat (14)
Bat (3)
Bovine (3)
Chicken (3)
Chimpanzee (3)
Dog (3)
Drosophila (3)
Gibbon (3)
Guinea pig (3)
Horse (3)
Insect (3)
Monkey (3)
Orangutan (3)
Pig (3)
Rabbit (3)
Xenopus (3)
Zebrafish (3)
IHC (9)
IHC-P (3)
WB (21)
DB (2)
ELISA (4)
ICC (3)
IF (5)
IP (3)
Peptide-ELISA (1)
rabbit (20)
mouse (5)
IgG (19)
IgG1 (3)
IgG2b (1)
monoclonal mc (5)
polyclonal pc (20)
25D5 (1)
2837C4a (2)
p45-110 (1)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
Unconjugated (19)
C-Terminus (4)
aa1-50 (2)
aa350-400 (1)
No (25)
PSMC5 / SUG1 Antibody - Immunohistochemical analysis of PSMC5 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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PSMC5 / SUG1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
50 µl/$286; 100 µl/$321; 200 µl/$386
PSMC5 / SUG1 Antibody - A: Marker, B: Jurkat Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PSMC5 / SUG1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Human
WB
Unconjugated
100 µl/$397
PSMC5 / SUG1 Antibody - A: Marker, B: Jurkat Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PSMC5 / SUG1 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody
Xenopus, Chicken, Zebrafish, Insect, Drosophila, Pig, Horse, Bovine, Rabbit, Mouse, Dog, Guinea pig, Bat, Rat, Gibbon, Human, Monkey, Orangutan, Chimpanzee
WB
HRP Conjugated
100 µl/$442
PSMC5 / SUG1 Antibody - A: Marker, B: Jurkat Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PSMC5 / SUG1 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Xenopus, Chicken, Zebrafish, Insect, Drosophila, Pig, Horse, Bovine, Rabbit, Mouse, Dog, Guinea pig, Bat, Rat, Gibbon, Human, Monkey, Orangutan, Chimpanzee
WB
Biotin Conjugated
100 µl/$442
PSMC5 / SUG1 Antibody - A: Marker, B: Jurkat Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PSMC5 / SUG1 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Xenopus, Chicken, Zebrafish, Insect, Drosophila, Pig, Horse, Bovine, Rabbit, Mouse, Dog, Guinea pig, Bat, Rat, Gibbon, Human, Monkey, Orangutan, Chimpanzee
WB
FITC Conjugated
100 µl/$442
PSMC5 / SUG1 Antibody - Immunostaining analysis in HeLa cells. HeLa cells were fixed with 4% paraformaldehyde and permeabilized with 0.1% Triton X-100 in PBS. The cells were immunostained with anti-PSMC5 mAb.
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PSMC5 / SUG1 Mouse anti-Human Monoclonal (2837C4a) Antibody
Mouse, Rat, Human
DB, ICC, IF, WB
Unconjugated
100 µg/$486
PSMC5 / SUG1 Antibody - Immunohistochemistry of paraffin-embedded human lung cancer tissue.
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PSMC5 / SUG1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
PSMC5 / SUG1 Antibody - Detection of Human TRIP1(SUG1) by Immunohistochemistry. Sample: FFPE section of human metastatic lymph node. Antibody: Affinity purified rabbit anti-TRIP1(SUG1) used at a dilution of 1:200 (1 ug/ml). Detection: DAB.
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PSMC5 / SUG1 Rabbit anti-Human Polyclonal (aa1-50) Antibody
Mouse, Human
IHC, IHC-P, IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
PSMC5 / SUG1 Antibody - Immunofluorescent analysis of PC3 cells diluted at 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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PSMC5 / SUG1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, WB
Unconjugated
50 µg/$294; 100 µg/$360
Select
PSMC5 / SUG1 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
PSMC5 / SUG1 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
PSMC5 / SUG1 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
PSMC5 / SUG1 Antibody - Western blot of Proteasome 19S ATPase subunit Rpt6monoclonal antibody (p45-110). Antibody dilution 1:1000 (lane a) and 1:5000 (lane b) using ECL procedure.
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PSMC5 / SUG1 Mouse anti-Human Monoclonal (p45-110) Antibody
Mouse, Rat, Human
IHC, IP, WB
Unconjugated
100 µl/$564
PSMC5 / SUG1 Antibody - Western blot of immunized recombinant protein using PSMC5 antibody.
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PSMC5 / SUG1 Mouse anti-Human Monoclonal (2837C4a) Antibody
Mouse, Rat, Human
DB, ICC, WB
Unconjugated
100 µg/$965
PSMC5 / SUG1 Antibody - 1:100 staining mouse brain tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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PSMC5 / SUG1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
PSMC5 / SUG1 Antibody - Detection of Human TRIP1/SUG1 by Immunohistochemistry. Sample: FFPE section of human metastatic bone marrow. Antibody: Affinity purified rabbit anti-TRIP1/SUG1 used at a dilution of 1:250.
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PSMC5 / SUG1 Rabbit anti-Human Polyclonal (aa1-50) Antibody
Mouse, Human
IHC, IHC-P
Unconjugated
2.5 µg/$295; 100 µl/$532
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PSMC5 / SUG1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
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PSMC5 / SUG1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
PSMC5 / SUG1 Antibody - Western blot of extracts of A431 cell and HepG2 cell lines, using PSMC5 antibody.
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PSMC5 / SUG1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µl/$356; 100 µl/$461
PSMC5 / SUG1 Antibody - Immunohistochemistry of paraffin-embedded human lung cancer using PSMC5 antibody at dilution of 1:100 (40x lens).
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PSMC5 / SUG1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
Select
PSMC5 / SUG1 Rabbit anti-Human Polyclonal (aa350-400) Antibody
Mouse, Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
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PSMC5 / SUG1 Mouse anti-Human Monoclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µg/$786
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PSMC5 / SUG1 Mouse anti-Human Monoclonal (25D5) Antibody
Human
WB
Unconjugated
100 µl/$450
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PSMC5 / SUG1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µg/$357
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PSMC5 / SUG1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µg/$357
Viewing 1-25 of 25 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).