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PSMC3IP

PSMC3 interacting protein

Plays an important role in meiotic recombination. Stimulates DMC1-mediated strand exchange required for pairing homologous chromosomes during meiosis. The complex PSMC3IP/MND1 binds DNA, stimulates the recombinase activity of DMC1 as well as DMC1 D-loop formation from double-strand DNA. This complex stabilizes presynaptic RAD51 and DMC1 filaments formed on single strand DNA to capture double-strand DNA. This complex stimulates both synaptic and presynaptic critical steps in RAD51 and DMC1-promoted homologous pairing. May inhibit HIV-1 viral protein TAT activity and modulate the activity of proteasomes through association with PSMC3. Acts as a tissue specific coactivator of hormone-dependent transcription mediated by nuclear receptors.

Gene Name: PSMC3 interacting protein
Synonyms: PSMC3IP, DBD-interacting, HOP2, HUMGT198A, GT198, PSMC3-interacting protein, TBP-1-interacting protein, ODG3, PSMC3 interacting protein, TBPIP
Target Sequences: NM_013290 NP_037422.2 Q9P2W1

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Proteins (3)
Over-Expression Lysate (2)
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PSMC3IP (3)
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Myc-DDK (Flag) (3)
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293T Cells (1)
HEK 293 Cells (2)
PSMC3IP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
23.5 kDa
100 µg/$494
PSMC3IP Protein - Purified recombinant protein PSMC3IP was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
23.5 kDa
20 µg/$1,107
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293T Cells
Myc-DDK (Flag)
23.5 kDa
20 µg/$150
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).