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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

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Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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PSMC1

proteasome (prosome, macropain) 26S subunit, ATPase, 1

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. This subunit and a 20S core alpha subunit interact specifically with the hepatitis B virus X protein, a protein critical to viral replication. This subunit also interacts with the adenovirus E1A protein and this interaction alters the activity of the proteasome. Finally, this subunit interacts with ataxin-7, suggesting a role for the proteasome in the development of spinocerebellar ataxia type 7, a progressive neurodegenerative disorder.

Gene Name: proteasome (prosome, macropain) 26S subunit, ATPase, 1
Family/Subfamily: ATPase , not assigned-ATPase
Synonyms: PSMC1, p26S4, S4, p56
Target Sequences: NM_002802 NP_002793.2 P62191

Filtered by: None
Target
PSMC1 (26)
Reactivity
Human (26)
Mouse (24)
Rat (13)
Bat (8)
Bovine (8)
Chicken (8)
Chimpanzee (6)
Dog (8)
Drosophila (4)
Gibbon (6)
Guinea pig (8)
Horse (8)
Monkey (9)
Pig (8)
Rabbit (8)
Xenopus (8)
Zebrafish (8)
Application
IHC (5)
WB (26)
Flo (1)
ELISA (4)
ICC (2)
IF (2)
IP (2)
Host
rabbit (25)
mouse (1)
Isotype
IgG (7)
IgG1 (1)
Clonality
monoclonal mc (1)
polyclonal pc (25)
Clone
5B6 (1)
Format
APC (1)
APC Conjugated (1)
Biotin Conjugated (3)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (1)
Unconjugated (13)
Epitope
aa1-440 (8)
aa269-318 (4)
aa71-120 (4)
aa390-440 (1)
aa408-436 (1)
aa50-100 (1)
Publications
No (26)
Showing 1-25 of 26 results

PSMC1 Antibody (clone 5B6) LS-C758809
Mouse Monoclonal [clone 5B6] (IgG1) to Human PSMC1
Mouse, Human
Flo, ICC, IF, IHC, WB
Unconjugated
100µl  $445.00
SMC1 Antibody in Immunohistochemistry (IHC)
SMC1 Antibody in Immunofluorescence (IF)

PSMC1 Antibody LS-C401947
Rabbit Polyclonal (IgG) to Human PSMC1
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20µl 0.5mg/ml  $205.00; 60µl 0.5mg/ml  $235.00; 120µl 0.5mg/ml  $295.00; 200µl 0.5mg/ml  $395.00
Immunohistochemistry of paraffin-embedded Human thyroid cancer using PSMC1 Polyclonal Antibody at dilution of 1:40.
Immunohistochemistry of paraffin-embedded Human brain using PSMC1 Polyclonal Antibody at dilution of 1:40.

PSMC1 Antibody LS-C405258
Rabbit Polyclonal (IgG) to Human PSMC1
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20µl 0.3mg/ml  $205.00; 60µl 0.3mg/ml  $235.00; 120µl 0.3mg/ml  $295.00; 200µl 0.3mg/ml  $395.00
Immunohistochemistry of paraffin-embedded Human thyroid cancer using PSMC1 Polyclonal Antibody at dilution of 1:25.
Immunohistochemistry of paraffin-embedded Human brain using PSMC1 Polyclonal Antibody at dilution of 1:25.

PSMC1 Antibody LS-C408288
Rabbit Polyclonal (IgG) to Human PSMC1
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
100µl  $295.00; 200µl  $385.00
Western blot analysis of extracts of various cell lines, using PSMC1 antibody. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking.

PSMC1 Antibody (aa1-440) LS-C314952
Rabbit Polyclonal to Human PSMC1
Mouse, Human
ICC, IP, WB
Unconjugated
20µl 0.5mg/ml  $205.00; 100µl 0.5mg/ml  $255.00; 200µl 0.5mg/ml  $305.00; 1ml 0.5mg/ml  $530.00
Western blot of recombinant PSMC1 / P56.
Western Blot; Sample: Recombinant PSMC1, Human.

PSMC1 Antibody (aa1-440, HRP) LS-C712398
Rabbit Polyclonal to Human PSMC1
Mouse, Human
WB
HRP Conjugated
100µl 0.5mg/ml  $285.00; 200µl 0.5mg/ml  $345.00; 1ml 0.5mg/ml  $680.00
Western blot of recombinant PSMC1 / P56.
Western Blot; Sample: Recombinant PSMC1, Human.

PSMC1 Antibody (aa1-440, Biotin) LS-C687794
Rabbit Polyclonal to Human PSMC1
Mouse, Human
WB
Biotin Conjugated
100µl 0.5mg/ml  $265.00; 200µl 0.5mg/ml  $315.00; 1ml 0.5mg/ml  $575.00
Western blot of recombinant PSMC1 / P56.
Western Blot; Sample: Recombinant PSMC1, Human.

PSMC1 Antibody (aa1-440, FITC) LS-C694691
Rabbit Polyclonal to Human PSMC1
Mouse, Human
WB
FITC Conjugated
100µl 0.5mg/ml  $275.00; 200µl 0.5mg/ml  $325.00; 1ml 0.5mg/ml  $635.00
Western blot of recombinant PSMC1 / P56.
Western Blot; Sample: Recombinant PSMC1, Human.

PSMC1 Antibody (aa1-440, PE) LS-C726459
Rabbit Polyclonal to Human PSMC1
Mouse, Human
WB
PE Conjugated
100µl 0.1mg/ml  $245.00; 200µl 0.1mg/ml  $285.00; 1ml 0.1mg/ml  $475.00
Western blot of recombinant PSMC1 / P56.
Western Blot; Sample: Recombinant PSMC1, Human.

PSMC1 Antibody (aa1-440, APC, Cy7) LS-C735387
Rabbit Polyclonal to Human PSMC1
Mouse, Human
WB
APC, Cy7 Conjugated
100µl 0.1mg/ml  $385.00; 200µl 0.1mg/ml  $475.00; 1ml 0.1mg/ml  $1,170.00
Western blot of recombinant PSMC1 / P56.
Western Blot; Sample: Recombinant PSMC1, Human.

PSMC1 Antibody (aa1-440, Cy3) LS-C703375
Rabbit Polyclonal to Human PSMC1
Mouse, Human
WB
Cy3 Conjugated
100µl 0.1mg/ml  $355.00; 200µl 0.1mg/ml  $445.00; 1ml 0.1mg/ml  $1,050.00
Western blot of recombinant PSMC1 / P56.
Western Blot; Sample: Recombinant PSMC1, Human.

PSMC1 Antibody (aa1-440, APC) LS-C718272
Rabbit Polyclonal to Human PSMC1
Mouse, Human
WB
APC Conjugated
100µl 0.1mg/ml  $275.00; 200µl 0.1mg/ml  $315.00; 1ml 0.1mg/ml  $590.00
Western blot of recombinant PSMC1 / P56.
Western Blot; Sample: Recombinant PSMC1, Human.

PSMC1 Antibody (aa390-440) LS-C290471
Rabbit Polyclonal (IgG) to Human PSMC1
Mouse, Human
IHC, IP, WB
Unconjugated
100µl 1mg/ml  $395.00

PSMC1 Antibody LS-C752202
Rabbit Polyclonal (IgG) to Human PSMC1
Human
ELISA, WB
Unconjugated
100µg  $335.00

PSMC1 Antibody LS-C803118
Rabbit Polyclonal (IgG) to Human PSMC1
Mouse, Rat, Human, Monkey
ELISA, WB
Unconjugated
100µl 1mg/ml  $325.00; 200µl 1mg/ml  $375.00
Western blot Image

PSMC1 Antibody (aa71-120) LS-C146282
Rabbit Polyclonal to Mouse PSMC1
Xenopus, Chicken, Zebrafish, Pig, Horse, Bat, Rat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey
WB
Unconjugated
100µl 0.5mg/ml  $365.00
PSMC1 antibody Western blot of Mouse Heart lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

PSMC1 Antibody (aa71-120, HRP) LS-C461811
Rabbit Polyclonal to Mouse PSMC1
Xenopus, Chicken, Zebrafish, Pig, Horse, Bat, Rat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Chimpanzee
WB
HRP Conjugated
100µl 0.65mg/ml  $385.00
PSMC1 antibody Western blot of Mouse Heart lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

PSMC1 Antibody (aa71-120, Biotin) LS-C461809
Rabbit Polyclonal to Mouse PSMC1
Xenopus, Chicken, Zebrafish, Pig, Horse, Bat, Rat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Chimpanzee
WB
Biotin Conjugated
100µl 1mg/ml  $385.00
PSMC1 antibody Western blot of Mouse Heart lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

PSMC1 Antibody (aa71-120, FITC) LS-C461810
Rabbit Polyclonal to Mouse PSMC1
Xenopus, Chicken, Zebrafish, Pig, Horse, Bat, Rat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Chimpanzee
WB
FITC Conjugated
100µl 1mg/ml  $385.00
PSMC1 antibody Western blot of Mouse Heart lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

PSMC1 Antibody (aa269-318) LS-C135384
Rabbit Polyclonal to Mouse PSMC1
Xenopus, Chicken, Zebrafish, Drosophila, Pig, Horse, Bat, Rat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey
WB
Unconjugated
100µl 0.5mg/ml  $365.00
PSMC1 antibody Western blot of Mouse Brain lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

PSMC1 Antibody (aa269-318, Biotin) LS-C461812
Rabbit Polyclonal to Mouse PSMC1
Xenopus, Chicken, Zebrafish, Drosophila, Pig, Horse, Bat, Rat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Chimpanzee
WB
Biotin Conjugated
100µl 1mg/ml  $385.00
PSMC1 antibody Western blot of Mouse Brain lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

PSMC1 Antibody (aa269-318, FITC) LS-C461813
Rabbit Polyclonal to Mouse PSMC1
Xenopus, Chicken, Zebrafish, Drosophila, Pig, Horse, Bat, Rat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Chimpanzee
WB
FITC Conjugated
100µl 1mg/ml  $385.00
PSMC1 antibody Western blot of Mouse Brain lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

PSMC1 Antibody (aa50-100) LS-C290466
Rabbit Polyclonal (IgG) to Human PSMC1
Mouse, Human
WB
Unconjugated
100µl 1mg/ml  $395.00

PSMC1 Antibody (aa408-436) LS-C203998
Rabbit Polyclonal to Human PSMC1
Mouse, Rat, Human
WB
Unconjugated
400µl  $325.00
PRS4 Antibody western blot of A549,HeLa cell line and mouse heart and lung,rat lung tissue lysates (35 ug/lane). The PRS4 antibody detected the PRS4 protein (arrow).

PSMC1 Antibody LS-C343765
Rabbit Polyclonal to Human PSMC1
Human
WB
Unconjugated
100µl  $425.00
Western blot of Rpt2/S4 19S regulatory subunit. Lane 1: Purified 26S proteasome. Lane 2: HeLa S100 cytosolic fraction . PAb to Proteasome 19S (Rpt2/S4 Subunit) (human) at 1:1000 dilution.
Showing 1-25 of 26 results

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PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).