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PSMB6
proteasome (prosome, macropain) subunit, beta type, 6
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. The encoded protein is a member of the proteasome B-type family, also known as the T1B family, and is a 20S core beta subunit in the proteasome. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
| Gene Name: | proteasome (prosome, macropain) subunit, beta type, 6 |
| Family/Subfamily: | Protease Non Catalytic , Threonine T1 |
| Synonyms: | PSMB6, LMPY, Proteasome catalytic subunit 1, Proteasome delta chain, Proteasome subunit beta type-6, Proteasome subunit delta, Proteasome subunit Y, Macropain delta chain |
| Target Sequences: | BC000835 P28072 P28072 |
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