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PSMB5

proteasome (prosome, macropain) subunit, beta type, 5

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit in the proteasome. This catalytic subunit is not present in the immunoproteasome and is replaced by catalytic subunit 3i (proteasome beta 8 subunit). Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Name: proteasome (prosome, macropain) subunit, beta type, 5
Family/Subfamily: Protease , Threonine T1
Synonyms: PSMB5, Proteasome chain 6, Proteasome subunit MB1, Proteasome subunit X, Proteasome catalytic subunit 3, Macropain epsilon chain, MB1, LMPX, Proteasome beta 5 subunit, Proteasome epsilon chain, Proteasome subunit beta type-5
Target Sequences: NM_002797 NP_002788.1 P28074

Publications (2)

1
Uncommon functional properties of the first piscine 26S proteasome from the Antarctic notothenioid Trematomus bernacchii. Gogliettino M, Balestrieri M, Riccio A, Facchiano A, Fusco C, Palazzo VC, Rossi M, Cocca E, Palmieri G. Bioscience reports. 2016 36: (WB; Human) [Full Text Article] [PubMed:26933238] [PMC:PMC4832319] Related Antibodies: LS-C111925.
2
Unusual Antioxidant Properties of 26S Proteasome Isolated from Cold-Adapted Organisms. Gogliettino M, Cocca E, Fusco C, Agrillo B, Riccio A, Balestrieri M, Facchiano A, Pepe A, Palmieri G. International journal of molecular sciences. 2017 18: (WB; Human) [Full Text Article] [PubMed:28757562] [PMC:PMC5577997] Related Antibodies: LS-C111925.

☰ Filters
Antibodies (25)
Proteins (8)
Over-Expression Lysate (4)
Primary (25)
Recombinant (4)
PSMB5 (33)
Human (24)
Mouse (11)
Rat (9)
Bat (4)
Bovine (4)
Chimpanzee (3)
Dog (4)
Gibbon (3)
Guinea pig (3)
Hamster (4)
Horse (4)
Monkey (4)
Orangutan (3)
Pig (4)
Rabbit (4)
Xenopus (4)
Zebrafish (4)
IHC (16)
IHC-P (4)
WB (21)
ELISA (11)
ICC (1)
IF (6)
IP (1)
Peptide-ELISA (1)
rabbit (24)
goat (1)
Product Group
IHCPlus (2)
IgG (15)
polyclonal pc (25)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (1)
Unconjugated (14)
aa235-263 (7)
aa72-121 (4)
C-Terminus (1)
aa213-263 (1)
No (32)
Yes (1)
GST (1)
GST, N-terminus (1)
His (1)
Myc-DDK (Flag) (5)
Human (6)
293T Cells (2)
E. coli (1)
HEK 293 Cells (3)
Wheat Germ Extract (2)
Purified (2)
PSMB5 Antibody - Anti-PSMB5 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.
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PSMB5 Goat anti-Human Polyclonal Antibody
Xenopus, Zebrafish, Pig, Horse, Rat, Hamster, Rabbit, Mouse, Dog, Bovine, Bat, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$460
PSMB5 Antibody - PSMB5 antibody Western blot of MCF7 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PSMB5 Rabbit anti-Human Polyclonal (aa72-121) Antibody
Human
WB
Unconjugated
100 µl/$424
PSMB5 Antibody - PSMB5 antibody Western blot of MCF7 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PSMB5 Rabbit anti-Human Polyclonal (aa72-121) (HRP) Antibody
Xenopus, Zebrafish, Rat, Hamster, Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Gibbon, Orangutan, Human, Monkey, Chimpanzee
WB
HRP Conjugated
100 µl/$469
PSMB5 Antibody - PSMB5 antibody Western blot of MCF7 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PSMB5 Rabbit anti-Human Polyclonal (aa72-121) (Biotin) Antibody
Xenopus, Zebrafish, Rat, Hamster, Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Gibbon, Orangutan, Human, Monkey, Chimpanzee
WB
Biotin Conjugated
100 µl/$469
PSMB5 Antibody - PSMB5 antibody Western blot of MCF7 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PSMB5 Rabbit anti-Human Polyclonal (aa72-121) (FITC) Antibody
Xenopus, Zebrafish, Rat, Hamster, Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Gibbon, Orangutan, Human, Monkey, Chimpanzee
WB
FITC Conjugated
100 µl/$469
PSMB5 Antibody - Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)
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PSMB5 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$460
PSMB5 Antibody - Immunohistochemical analysis of PSMB5 staining in human stomach formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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PSMB5 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
50 µl/$286; 100 µl/$321; 200 µl/$386
PSMB5 Antibody - Detection of Human PSMB5 by Western Blot. Samples: Whole cell lysate from 293T (15 and 50 ug), HeLa (H; 50 ug), and Jurkat (J; 50 ug) cells. Antibodies: Affinity purified rabbit anti-PSMB5 antibody used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 10 seconds.
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PSMB5 Rabbit anti-Human Polyclonal (aa213-263) Antibody
Human
IHC, IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
PSMB5 Antibody - 1:100 staining human breast carcinoma tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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PSMB5 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
PSMB5 Antibody - Immunohistochemistry of paraffin-embedded human breast cancer using PSMB5 Antibody at dilution of 1:100
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PSMB5 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$294; 100 µg/$360
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PSMB5 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
PSMB5 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
PSMB5 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
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PSMB5 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$331
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PSMB5 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
PSMB5 Antibody - PSMB5 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human skin tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
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PSMB5 Rabbit anti-Human Polyclonal (aa235-263) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
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PSMB5 Rabbit anti-Human Polyclonal (aa235-263) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
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PSMB5 Rabbit anti-Human Polyclonal (aa235-263) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
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PSMB5 Rabbit anti-Human Polyclonal (aa235-263) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
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PSMB5 Rabbit anti-Human Polyclonal (aa235-263) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
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PSMB5 Rabbit anti-Human Polyclonal (aa235-263) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
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PSMB5 Rabbit anti-Human Polyclonal (aa235-263) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
PSMB5 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, WB
Unconjugated
50 µl/$356; 100 µl/$461
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PSMB5 Rabbit anti-Human Polyclonal Antibody
Human
IHC, WB
Unconjugated
100 µl/$543
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PSMB5 Rabbit anti-Mouse Polyclonal (C-Terminus) Antibody
Mouse
WB
Unconjugated
100 µg/$1,202
Viewing 1-25 of 33 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).